Culture of adult rat lung cells: Benzo(a)pyrene metabolism and mutagenesis

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.

1975 • 3,362 citations

Carcinogenesis by chemicals: an overview--G. H. A. Clowes memorial lecture.

1970 • 1,464 citations

CLONAL GROWTH OF MAMMALIAN CELLS IN VITRO

1956 • 1,130 citations

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals: discussion.

1976 • 850 citations

Leukocytes Cultured from Small Inocula of Whole Blood and the Preparation of Metaphase Chromosomes by Treatment with Hypotonic KCL

1965 • 573 citations

Survey of Compounds Which Have Been Tested for Carcinogenic Activity

1942 • 354 citations

The type II epithelial cell of the lung. I. Method of isolation.

1974 • 313 citations

Cell‐mediated mutagenesis of mammalian cells with chemical carcinogens

1974 • 243 citations

Chemical Oncogenesis In Culture

1973 • 192 citations

Maintenance of cytochrome P-450 and metabolism of aflatoxin B1 in primary hepatocyte cultures

1977 • 178 citations

Liver homogenate-mediated mutagenesis in Chinese hamster V79 cells by polycyclic aromatic hydrocarbons and aflatoxins

1977 • 150 citations

Mutability of different genetic loci in mammalian cells by metabolically activated carcinogenic polycyclic hydrocarbons.

1976 • 148 citations

Metabolism of benzo[a]pyrene

1975 • 148 citations

Clonal isolation of differentiated rat lung cells

1974 • 142 citations

Liver cell-mediated mutagenesis of mammalian cells by liver carcinogens.

1978 • 138 citations

Effects of physical training in intermittent claudication

1978 • 135 citations

Benzo(a)pyren-3-yl hydrogen sulphate, a major ethyl acetate-extractable metabolite of benzo(a)pyrene in human, hamster and rat lung cultures

1976 • 110 citations

Soft Agar Techniques

1973 • 109 citations

Human pulmonary alveolar macrophages metabolise benzo(a)pyrene to proximate and ultimate mutagens

1978 • 103 citations

Microsome-mediated mutagenesis in V79 Chinese hamster cells by various nitrosamines.

1977 • 102 citations

Differences between products of binding of 7,12-dimethylbenz[a]anthracene to DNA in mouse skin and in a rat liver microsomal system

1978 • 100 citations

Advances in Cancer Research

1953 • 84 citations

Metabolism of polycyclic aromatic hydrocarbons in cell cultuires.

1971 • 77 citations

Cell-mediated mutagenesis in cultured Chinese hamster cells by carcinogenic polycyclic hydrocarbons: Nature and extent of the associated hydrocarbon-DNA reaction

1977 • 71 citations

Metabolism of benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in cultured human bronchus and pancreatic duct.

1977 • 65 citations

Benzo[α]pyrene carcinogenesis: A biochemical selection mechanism

1977 • 62 citations

Rat Hepatocyte Primary Cell Culture-Mediated Mutagenesis of Adult Rat Liver Epithelial Cells by Procarcinogens

1977 • 60 citations

Increased in vitro growth capacity of tracheal epithelium exposed in vivo to 7, 12-dimethylbenz(a)anthracene.

1977 • 59 citations

Direct or proximate contact between cells and metabolic activation systems is required for mutagenesis

1978 • 57 citations

Explant culture of human peripheral lung. I. Metabolism of benzo[alpha]pyrene.

1978 • 49 citations

Human bronchus-mediated mutagenesis of mammalian cells by carcinogenic polynuclear aromatic hydrocarbons.

1978 • 46 citations

Metabolism of [3H]benzo(a)pyrene by different portions of the respiratory tract

1976 • 45 citations

Metabolism and covalent binding of [3H]benzo(a)pyrene by isolated perfused lungs and short-term tracheal organ culture of cigarette smoke-exposed rats.

1977 • 41 citations

Characteristics of epithelial cella cultured from feline lung.

1976 • 32 citations

Metabolism of dimethylnitrosamine and 1,2-dimethylhydrazine in cultured human bronchi.

1977 • 31 citations

A comparison of benzo(a)pyrene metabolism by liver and lung microsomal enzymes from 3-methylcholanthrene-treated rhesus monkeys and rats.

1977 • 27 citations

The effects of cigarette smoke on the metabolism of [3H]benzo(a)pyrene by rat lung microsomes.

1977 • 26 citations

Metabolism of 7,12-dimethylbmethylbenz(a)anthracene by macrophages and uptake of macrophage-derived metabolites by respiratory tissues in vitro.

1978 • 15 citations

THE BLOOD TECHNIQUE AND HUMAN CHROMOSOMES

1964 • 6 citations