Induction of hepatic cytochrome P-450 by natural steroids: Relationship to the induction of δ-aminolevulinate synthase and porphyrin accumulation in the avian embryo

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The Carbon Monoxide-binding Pigment of Liver Microsomes

1964 • 11,832 citations

The Metabolic Basis of Inherited Disease.

1988 • 7,933 citations

The Metabolic Basis of Inherited Disease.

1983 • 2,885 citations

The Induction in Vitro of the Synthesis of δ-Aminolevulinic Acid Synthetase in Chemical Porphyria: A Response to Certain Drugs, Sex Hormones, and Foreign Chemicals

1966 • 764 citations

Effects by heme, insulin, and serum albumin on heme and protein synthesis in chick embryo liver cells cultured in a chemically defined medium, and a spectrofluorometric assay for porphyrin composition.

1975 • 303 citations

Metabolic Effects of Gonadal Hormones and Contraceptive Steroids

1969 • 235 citations

Steroid Induction of Porphyrin Synthesis in Liver Cell Culture

1967 • 156 citations

Steroid Induction of Porphyrin Synthesis in Liver Cell Culture

1968 • 145 citations

Heme biosynthesis and drug metabolism in mice with hereditary hemolytic anemia. Heme oxygenase induction as an adaptive response for maintaining cytochrome P-450 in chronic hemolysis.

1979 • 95 citations

Formation and disposition of newly synthesized heme in adult rat hepatocytes in primary culture.

1981 • 53 citations

Steroid induction of delta-aminolevulinic acid synthase and porphyrins in liver. Structure-activity studies and the permissive effects of hormones on the induction process.

1979 • 52 citations

Drug stimulation of -aminolevulinic acid synthetase and cytochrome P-450 in vivo in chick embryo liver.

1973 • 51 citations

Studies in porphyria

1979 • 48 citations

Neonatal imprinting and the turnover of microsomal cytochrome P-450 in rat liver.

1975 • 47 citations

Genetic, Metabolic, and Biochemical Aspects of the Porphyrias

1981 • 43 citations

STUDIES IN PORPHYRIA

1972 • 42 citations

The interaction of steroids with liver microsomal cytochrome P-450—A general hypothesis

1975 • 41 citations

Studies in porphyria; v. Drug oxidation rates in hereditary hepatic porphyria

1976 • 38 citations

STUDIES IN PORPHYRIA

1973 • 38 citations

Effects of antihypertensive drugs on hepatic heme biosynthesis, and evaluation of ferrochelatase inhibitors to simplify testing of drugs for heme pathway induction

1978 • 32 citations

In vitro inhibition of drug metabolism by metabolites of progesterone.

1972 • 32 citations

Androgen Receptor Dependent and Independent Activities of Testosterone on Hepatic Microsomal Drug Metabolism¹²

1976 • 29 citations

17-Oxosteroid Conjugates in Plasma and Urine of Patients with Acute Intermittent Porphyria

1974 • 27 citations

Diseases of the Liver (5th ed.)

1983 • 26 citations

Maintenance of microsomal hemoprotein concentrations following inhibition of ferrochelatase activity by 3,5-diethoxycarbonyl-1,4-dihydrocollidine in chick embryo liver.

1979 • 23 citations

Further studies on the inhibition of drug metabolism by pregnanolone and related steroids

1974 • 23 citations

Effect of the Tfin Locus on the Hepatic Ethylmorphine JV-Demethylase System in Mice*

1978 • 22 citations

Porphyrin-Heme Pathway: Regulation by Intermediates in Bile Acid Synthesis

1973 • 20 citations

INVESTIGATIONS INTO THE POSSIBLE EFFECTS OF NATURALLY OCCURRING STEROIDS ON BIOSYNTHESIS OF 16-ANDROSTENES AND ANDROGENS IN MICROSOMES OF BOAR TESTIS

1981 • 13 citations

Porphyrin Induction: Equivalent Effects of 5αH and 5βH Steroids in Chick Embryo Liver Cells

1977 • 12 citations

Macromolecular binding of 5β-H steroids in chick embryo liver

1981 • 5 citations