Use of second-site suppressor mutations in Drosophila to identify components of the transcriptional machinery.

How eukaryotic transcriptional activators work

1988 • 1,924 citations

The induction of gene activity in drosophila by heat shock

1979 • 1,308 citations

A cellular DNA-binding protein that activates eukaryotic transcription and DNA replication

1987 • 1,050 citations

Five intermediate complexes in transcription initiation by RNA polymerase II

1989 • 1,033 citations

Proteins as molecular chaperones

1987 • 910 citations

Polypeptide chain binding proteins: Catalysts of protein folding and related processes in cells

1989 • 884 citations

Multiple factors required for accurate initiation of transcription by purified RNA polymerase II.

1980 • 541 citations

A Drosophila RNA polymerase II transcription factor contains a promoter-region-specific DNA-binding activity

1984 • 537 citations

Eukaryotic RNA Polymerase

1985 • 500 citations

Preparation, molecular weight, base composition, and secondary structure of giant nuclear ribonucleic acid

1973 • 375 citations

Eucaryotic RNA Polymerase Conditional Mutant that Rapidly Ceases mRNA Synthesis

1987 • 353 citations

Separation and characterization of factors mediating accurate transcription by RNA polymerase II.

1982 • 314 citations

Functional redundancy and structural polymorphism in the large subunit of RNA polymerase II

1987 • 306 citations

Suppressors of yeast actin mutations.

1989 • 286 citations

Conditional-lethal mutations that suppress genetic defects in morphogenesis by altering structural proteins.

1975 • 212 citations

Epistatic gene interactions in the control of division in fission yeast

1979 • 208 citations

Isolation of three proteins that bind to mammalian RNA polymerase II.

1985 • 203 citations

ETHYL METHANESULFONATE-INDUCED REVERSION OF BACTERIOPHAGE T4rII MUTANTS

1963 • 202 citations

Dynamic interaction between a Drosophila transcription factor and RNA polymerase II.

1989 • 191 citations

Interaction between cdc13+ and cdc2+ in the control of mitosis in fission yeast; dissociation of the G1 and G2 roles of the cdc2+ protein kinase.

1987 • 177 citations

A general transcription factor forms a stable complex with RNA polymerase B (II)

1987 • 175 citations

RNA Polymerase II Subunit RPB4 Is Essential for High- and Low-Temperature Yeast Cell Growth

1989 • 173 citations

Mechanisms of Suppression

1973 • 170 citations

RAP30/74: a general initiation factor that binds to RNA polymerase II.

1988 • 115 citations

α-amanitin-resistant D. melanogaster with an altered RNA polymerase II

1979 • 106 citations

Isolation and mapping of a cloned ribosomal protein gene of Drosophila melanogaster

1980 • 104 citations

Localization of an alpha-amanitin resistance mutation in the gene encoding the largest subunit of mouse RNA polymerase II.

1987 • 97 citations

Amanitin-resistant RNA polymerase II mutations are in the enzyme's largest subunit.

1983 • 89 citations

Genetic and biochemical characterization of mutants at an RNA polymerase II locus in D. melanogaster

1980 • 89 citations

Dominant suppressors of yeast actin mutations that are reciprocally suppressed.

1989 • 86 citations

Temperature-sensitive mutants blocked in the folding or subunit assembly of the bacteriophage P22 tail spike protein

1981 • 70 citations

Alteration of hsp82 gene expression by the gypsy transposon and suppressor genes in Drosophila melanogaster.

1989 • 69 citations

An RNA polymerase II mutation in Drosophila melanogaster that mimics ultrabithorax

1981 • 62 citations

A Caenorhabditis elegans RNA polymerase II gene, ama-1 IV, and nearby essential genes.

1988 • 59 citations

RNA polymerase II from wild type and alpha-amanitin-resistant strains of Caenorhabditis elegans.

1983 • 56 citations

Dynamic Interaction between a Drosophila Transcription Factor and RNA Polymerase II

1989 • 53 citations

The RNA polymerase II of an α-amanitin-resistant Chinese hamster ovary cell line

1976 • 44 citations

RAP30/74: A General Initiation Factor That Binds to RNA Polymerase II

1988 • 44 citations

Isolation and Characterization of Temperature-Sensitive Rna Polymerase II Mutants of Saccharomyces cerevisiae

1987 • 39 citations

Localization of an α-Amanitin Resistance Mutation in the Gene Encoding the Largest Subunit of Mouse RNA Polymerase II

1987 • 35 citations

Developmental effects of a temperature-sensitive RNA polymerase II mutation in Drosophila melanogaster

1984 • 29 citations

Antagonistic interactions between alleles of the RpII215 locus in Drosophila melanogaster.

1988 • 20 citations

Developmental genetics of a temperature-sensitive RNA polymerase II mutation in Drosophila melanogaster

1982 • 16 citations

Cloning and identification of the gene coding for the 140-kd subunit of Drosophila RNA polymerase II

1986 • 14 citations