Kinetics of hydrolysis of endocytosed substrates by mammalian cultured cells: Early introduction of lysosomal enzymes into the endocytic pathway

[41] Cathepsin B, cathepsin H, and cathepsin L

1981 • 1,678 citations

Antigen-Presenting Function of the Macrophage

1984 • 1,164 citations

The mannose 6-phosphate receptor and the biogenesis of lysosomes

1988 • 846 citations

Establishment and Characterization of BALB/c Lymphoma Lines with B Cell Properties

1979 • 677 citations

Low temperature selectively inhibits fusion between pinocytic vesicles and lysosomes during heterophagy of 125I-asialofetuin by the perfused rat liver.

1980 • 451 citations

Endosomes

1983 • 416 citations

Penetration of semliki forest virus from acidic prelysosomal vacuoles

1983 • 411 citations

Endosome pH measured in single cells by dual fluorescence flow cytometry: rapid acidification of insulin to pH 6.

1984 • 275 citations

Possible pathways for lysosomal enzyme delivery.

1985 • 253 citations

A possible role for Na+,K+-ATPase in regulating ATP-dependent endosome acidification.

1989 • 229 citations

Regulation of endocytic pH by the Na+,K+-ATPase in living cells.

1989 • 228 citations

Macrophage endosomes contain proteases which degrade endocytosed protein ligands.

1985 • 223 citations

Studies in detoxication. 67. The biosynthesis of the glucuronides of umbelliferone and 4-methylumbelliferone and their use in fluorimetric determination of β-glucuronidase

1955 • 215 citations

The role of intermediate vesicles in the adsorptive endocytosis and transport of ligand to lysosomes by human fibroblasts.

1983 • 196 citations

Lysosomal acid phosphatase is transported to lysosomes via the cell surface.

1989 • 189 citations

Biosynthesis and turnover of the mannose 6-phosphate receptor in cultured Chinese hamster ovary cells.

1983 • 169 citations

ENDOCYTOSIS IN CHANG LIVER CELLS

1971 • 165 citations

Kinetics and temperature dependence of exposure of endocytosed material to proteolytic enzymes and low pH: Evidence for a maturation model for the formation of lysosomes

1987 • 126 citations

Kinetics of endosome acidification detected by mutant and wild-type Semliki Forest virus.

1986 • 115 citations

Flow cytometry : advanced research and clinical applications

1989 • 107 citations

Cell‐by‐cell autofluorescence correction for low signal‐to‐noise systems: Application to epidermal growth factor endocytosis by 3T3 fibroblasts

1986 • 99 citations

Internalization of insulin into rat liver Golgi elements. Evidence for vesicle heterogeneity and the path of intracellular processing.

1982 • 98 citations

Human cathepsin B. Application of the substrate N-benzyloxycarbonyl-<scp>l</scp>-arginyl-<scp>l</scp>-arginine 2-naphthylamide to a study of the inhibition by leupeptin

1980 • 91 citations

Inactivation of platelet activating factor by rabbit platelets. Lyso-platelet activating factor as a key intermediate with phosphatidylcholine as the source of arachidonic acid in its conversion to a tetraenoic acylated product.

1985 • 84 citations

Evidence for both prelysosomal and lysosomal intermediates in endocytic pathways.

1984 • 81 citations

High-resolution kinetics of transferrin acidification in BALB/c 3T3 cells: exposure to pH 6 followed by temperature-sensitive alkalinization during recycling.

1987 • 71 citations

Isolation of Three Acid Phosphatases from Wheat Germ

1969 • 63 citations

Oligopeptide antigens of the angiotensin lineage compete for presentation by paraformaldehyde-treated accessory cells to T cells.

1986 • 48 citations

Protein phosphorylation and oocyte maturation

1986 • 46 citations

Subcellular redistribution of newly synthesized macrophage lysosomal enzymes. Correlation between delivery to the lysosomes and maturation.

1983 • 44 citations

Recycling of epidermal growth factor in a human pancreatic carcinoma cell line.

1985 • 44 citations

Effects of temperature, pH elevators, and energy production inhibitors on horseradish peroxidase transport through endocytic vesicles

1987 • 44 citations

Acid phosphatases of human erythrocytes

1965 • 30 citations

Postendocytic maturation of acid hydrolases: evidence of prelysosomal processing.

1987 • 28 citations

Processing of Endocytosed Material

1988 • 23 citations

Effect of confluence on endocytosis by 3T3 fibroblasts: increased rate of pinocytosis and accumulation of residual bodies.

1989 • 22 citations

Fibroblasts maintain a complete endocytic pathway in the presence of lysosomotropic amines*1

1988 • 10 citations