The basic structural lesion of persistent neonatal hypoglycaemia with hyperinsulinism: deficiency of pancreatic D cells or hyperactivity of B cells?

Statistical methods

1967 • 19,533 citations

THE CORPUSCLE PROBLEM. A MATHEMATICAL STUDY OF A BIOMETRIC PROBLEM

1925 • 424 citations

Cellular composition of the human diabetic pancreas

1983 • 394 citations

Nesidioblastoma, the islet tumor of the pancreas.

1938 • 261 citations

THE CORPUSCLE PROBLEM. SECOND MEMOIR CASE OF ELLIPSOIDAL CORPUSCLES

1926 • 248 citations

Nesidioblastosis of the pancreas: definition of the syndrome and the management of the severe neonatal hyperinsulinaemic hypoglycaemia.

1981 • 207 citations

Cell populations in the endocrine pancreas of human neonates and infants

1981 • 174 citations

IDIOPATHIC SPONTANEOUSLY OCCURRING HYPOGLYCEMIA IN INFANTS<subtitle>Clinical Significance of Problem and Treatment</subtitle>

1954 • 171 citations

Nesidioblastosis: The Pathologic Basis of Persistent Hyperinsulinemic Hypoglycemia in Infants: Morphologic and Quantitative Analysis of Seven Cases Based on Specific Immunostaining and Electron Microscopy

1977 • 150 citations

Beta cell nesidioblastosis in idiopathic hypoglycemia of infancy

1971 • 146 citations

Pancreatic pathology in hyperinsulinemic hypoglycemia of infancy.

1980 • 144 citations

Neonatal and Infantile Hypoglycemia Due to Insulin Excess

1977 • 89 citations

Nesidioblastosis: the pathologic basis of persistent hyperinsulinemic hypoglycemia in infants. Morphologic and quantitative analysis of seven cases based on specific immunostaining and electron microscopy

1977 • 59 citations

Idiopathic hypoglycaemia in sibs with morphological evidence of nesidioblastosis of the pancreas.

1976 • 58 citations

Nesidioblastosis and other islet cell abnormalities in hyperinsulinemic hypoglycemia of childhood

1980 • 56 citations

Nesidiodysplasia and Nesidioblastosis of Infancy: Structural and Functional Correlations with the Syndrome of Hyperinsulinemic Hypoglycemia

1983 • 55 citations

A possible role for the exocrine pancreas in the pathogenesis of neonatal leucine-sensitive hypoglycemia

1970 • 50 citations

The pancreatic islet of infants with severe hypoglycemia.

1970 • 49 citations

Nesidioblastosis of the pancreas in infancy.

1981 • 48 citations

Clinical and histologic indications for extensive pancreatic resection in nesidioblastosis

1982 • 44 citations

Regulation in healthy subjects of the secretion of human pancreatic polypeptide, a newly recognized pancreatic islet polypeptide.

1976 • 43 citations

Diploid, Tetraploid and Octaploid Beta Cells in the Islets of Langerhans of the Normal Human Pancreas

1974 • 41 citations

Decrease of Pancreatic Somatostatin in Neonatal Nesidiobiastosis

1981 • 38 citations

Nesidioblastosis in Adults Without Insular Hyperfunction

1982 • 38 citations

Beta cell nesidioblastosis

1978 • 37 citations

Islet cell adenomatosis and adenoma in an infant

1971 • 34 citations

Renal function and cimetidine. Urinary albumin and beta 2-microglobulin excretion and creatine clearance during cimetidine treatment.

1981 • 30 citations

Near-Total Pancreatectomy in Persistent Infantile Hypoglycemia

1982 • 30 citations

Hyperinsulinemic Hypoglycemia of the Neonate Associated with Persistent Fetal Histology and Function of the Pancreas

1980 • 30 citations

Case 30-1978

1978 • 30 citations

Morphometric and ultrastructural studies in an infant with leucine-sensitive hypoglycemia, hyperinsulinism and islet hyperplasia

1974 • 29 citations

Hypoglycemia in Infancy Caused by Beta Cell Nesidioblastosis

1974 • 29 citations

The ultrastructure of focal islet cell adenomatosis in the newborn with hypoglycemia and hyperinsulinism

1975 • 27 citations

Polyploidy in the human endometrium with the Arias-Stella reaction.

1968 • 26 citations

Nesidiodysplasia and nesidioblastosis of infancy: ultrastructural and immunohistochemical analysis of islet cell alterations with and without associated hyperinsulinaemic hypoglycaemia.

1981 • 24 citations

Immunohistochemical, morphometric, and clinical studies of the pancreatic islets in infants with persistent neonatal hypoglycemia of familial type with hyperinsulinism and nesidioblastosis.

1981 • 24 citations

NESIDIOBLASTOSIS OF THE PANCREAS IN INFANCY

1981 • 23 citations

PERSISTENT NEONATAL HYPOGLYCAEMIA.

1975 • 19 citations

[Morphological criteria for the evaluation of islands of Langerhans activity].

1958 • 16 citations

Decrease of pancreatic somatostatin in neonatal nesidioblastosis

1981 • 14 citations

SIZE DIFFERENCES OF THE B‐CELL NUCLEI IN THE ISLET TISSUE OF NORMAL AND ALLOXAN‐TREATED RATS

1959 • 14 citations

Leucine-Induced Hypoglycemia

1962 • 13 citations

Idiopathic Hypoglycemia in Infancy

1974 • 11 citations

The ultrastructure of polyploid B-cells in the islets of normal mice

1976 • 10 citations

Islet Cell Hyperinsulinism in Adults and Children

1974 • 10 citations

Significance of Argyrophil Parenchymal Cells in the Pancreatic Islets in Persistent Neonatal Hypoglycemia with Hyperinsulinism of Familial Type

1981 • 9 citations

Leucine-Induced Hypoglycemia

1967 • 4 citations

Islet cell hyperinsulinism in adults and children

1974 • 2 citations

Nesidiodysplasia and nesidioblastosis of infancy: Structural and functional correlations with the syndrome of hyperinsulinemic hypoglycemia

1984 • 1 citations

Islet cell adenomatosis and adenoma in an infant

1972 • 1 citations