Different proteasome subtypes in a single tissue exhibit different enzymatic properties 1 1Edited by R. Huber

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Cleavage of structural proteins during the assemble of the head of bacterio-phage T4

1970 • 5,738 citations

High resolution two-dimensional electrophoresis of basic as well as acidic proteins

1977 • 3,556 citations

STRUCTURE AND FUNCTIONS OF THE 20S AND 26S PROTEASOMES

1996 • 2,408 citations

The Proteasome: Paradigm of a Self-Compartmentalizing Protease

1998 • 1,483 citations

Immunoproteasome Assembly: Cooperative Incorporation of Interferon γ (IFN-γ)–inducible Subunits

1998 • 430 citations

Identity of the 19S 'prosome' particle with the large multifunctional protease complex of mammalian cells (the proteasome)

1988 • 404 citations

Interferon-γ Induces Different Subunit Organizations and Functional Diversity of Proteasomes1

1994 • 371 citations

Interferon gamma stimulation modulates the proteolytic activity and cleavage site preference of 20S mouse proteasomes.

1994 • 314 citations

The MHC class I ligand‐generating system: roles of immunoproteasomes and the interferon‐4gMY‐inducible proteasome activator PA28

1998 • 288 citations

Purification and characterization of a multicatalytic high-molecular-mass proteinase from rat skeletal muscle

1985 • 208 citations

The subunits MECL-1 and LMP2 are mutually required for incorporation into the 20S proteasome

1997 • 208 citations

A Single Residue Exchange Within a Viral CTL Epitope Alters Proteasome-Mediated Degradation Resulting in Lack of Antigen Presentation

1996 • 181 citations

The prosome: an ubiquitous morphologically distinct RNP particle associated with repressed mRNPs and containing specific ScRNA and a characteristic set of proteins.

1984 • 180 citations

Subpopulations of proteasomes in rat liver nuclei, microsomes and cytosol

1996 • 172 citations

Proteasome Subunits X and Y Alter Peptidase Activities in Opposite Ways to the Interferon-γ-induced Subunits LMP2 and LMP7

1996 • 164 citations

Efficient Generation of a Hepatitis B Virus Cytotoxic T Lymphocyte Epitope Requires the Structural Features of Immunoproteasomes

2000 • 161 citations

The Multicatalytic Proteinase

1989 • 145 citations

Bovine Spleen Multicatalytic Proteinase Complex (Proteasome)

1997 • 133 citations

The Drosophila proteasome undergoes changes in its subunit pattern during development

1989 • 127 citations

Phosphorylation of Proteasomes in Mammalian Cells

1996 • 125 citations

The Sequence Alteration Associated with a Mutational Hotspot in p53 Protects Cells From Lysis by Cytotoxic T Lymphocytes Specific for a Flanking Peptide Epitope

1998 • 124 citations

Effects of interferon gamma and major histocompatibility complex-encoded subunits on peptidase activities of human multicatalytic proteases.

1995 • 80 citations

Sensitivity and variability of the Bradford protein assay in the presence of detergents

1989 • 77 citations

Duplicated Proteasome Subunit Genes in Drosophila melanogaster Encoding Testes-Specific Isoforms

1996 • 72 citations

Altered Properties of the Branched Chain Amino Acid-preferring Activity Contribute to Increased Cleavages after Branched Chain Residues by the “Immunoproteasome”

1998 • 67 citations

Inactivation of a Defined Active Site in the Mouse 20S Proteasome Complex Enhances Major Histocompatibility Complex Class I Antigen Presentation of a Murine Cytomegalovirus Protein

1998 • 55 citations

Studies on the activation by ATP of the 26 S proteasome complex from rat skeletal muscle

1995 • 37 citations

Identification and Characterization of Three Different Subpopulations of the Drosophila Multicatalytic Proteinase (Proteasome)

1989 • 34 citations

Differences in Catalytic Activities and Subunit Pattern of Multicatalytic Proteinase Complexes (Proteasomes) Isolated from Bovine Pituitary, Lung, and Liver

1995 • 31 citations

Phosphoamino Acids in Proteasome Subunits

1996 • 29 citations

Nuclear multicatalytic proteinase .alpha. subunit RRC3: Differential size, tyrosine phosphorylation, and susceptibility to antisense oligonucleotide treatment

1995 • 26 citations

Isolation and Characterization of Two 20S Proteasomes from the Endoplasmic Reticulum of Rat Liver Microsomes

1999 • 22 citations

Multicatalytic proteinase complex or multicatalytic proteinase: a high-Mr endopeptidase

1988 • 22 citations

Changes in the amount and distribution of prosomal subunits during the differentiation of U937 myeloid cells: high expression of p23K

1996 • 17 citations

Differential Expression of a Proteasomal Subunit during Chick Development

1997 • 13 citations

Tissue-specific expression of the subunits of chick 20S proteasomes.

1994 • 11 citations

Preferential Expression of the cDNA Encoding the Proteasome Subunit during the Growth/Differentiation Transition ofDictyosteliumCells

1998 • 10 citations

Changes in the subunit distribution of prosomes (MCP-proteasomes) during the differentiation of human leukemic cells

1997 • 9 citations