Nerve growth factor and nociception

Capsaicin: cellular targets, mechanisms of action, and selectivity for thin sensory neurons.

1991 • 1,760 citations

Trophic factors and neuronal survival

1989 • 1,631 citations

Interleukin-1 regulates synthesis of nerve growth factor in non-neuronal cells of rat sciatic nerve

1987 • 1,000 citations

Nerve growth factor regulates expression of neuropeptide genes in adult sensory neurons

1989 • 934 citations

Activity-dependent neuronal plasticity following tissue injury and inflammation

1992 • 933 citations

Peripheral and central mechanisms of cutaneous hyperalgesia

1992 • 896 citations

Increased content and transport of substance P and calcitonin gene-related peptide in sensory nerves innervating inflamed tissue: Evidence for a regulatory function of nerve growth factor in vivo

1992 • 603 citations

Nerve growth factor-induced hyperalgesia in the neonatal and adult rat

1993 • 560 citations

An Enzyme‐Linked Immunoassay for Nerve Growth Factor (NGF): A Tool for Studying Regulatory Mechanisms Involved in NGF Production in Brain and in Peripheral Tissues

1987 • 377 citations

Mast cells increase in tissues of neonatal rats injected with the nerve growth factor

1977 • 357 citations

Sensory Neurons: Diversity, Development and Plasticity

1993 • 344 citations

Peripheral Mechanisms of Somatic Pain

1988 • 319 citations

Activity‐Dependent Changes in Rat Ventral Horn Neurons in vitro; Summation of Prolonged Afferent Evoked Postsynaptic Depolarizations Produce a D‐2‐Amino‐5‐Phosphonovaleric Acid Sensitive Windup

1990 • 270 citations

Responsiveness and functional attributes of electrically localized terminals of cutaneous C-fibers in vivo and in vitro

1992 • 259 citations

The role of NGF in sensory neurons in vivo

1986 • 233 citations

Effect of nerve growth factor on the release of inflammatory mediators by mature human basophils

1992 • 227 citations

Nerve growth factor regulates sympathetic ganglion cell morphology and survival in the adult mouse

1990 • 227 citations

Sensory Neurons; Diversity, Development and Plasticity

1994 • 226 citations

Neuropeptide expression in cultures of adult sensory neurons: Modulation of substance P and calcitonin gene-related peptide levels by nerve growth factor

1989 • 221 citations

Nerve growth factor (NGF) regulates adult rat cultured dorsal root ganglion neuron responses to the excitotoxin capsaicin

1988 • 218 citations

Effects of long-term nerve growth factor deprivation on the nervous system of the adult rat: An experimental autoimmune approach

1980 • 210 citations

Cooperative regulation of nerve growth factor synthesis and secretion in fibroblasts and astrocytes by fibroblast growth factor and other cytokines

1992 • 207 citations

Somal membrane properties of physiologically identified sensory neurons in the rat: effects of nerve growth factor

1992 • 204 citations

The Role of Mast Cells in Inflammatory Processes: Evidence for Nerve/Mast Cell Interactions

1987 • 196 citations

Identification of the unmyelinated sensory nerves which evoke plasma extravasation in response to antidromic stimulation

1981 • 189 citations

Fine structure of myelinated mechanical nociceptor endings in cat hairy skin

1981 • 186 citations

Effect of nerve growth factor on the release of inflammatory mediators by mature human basophils

1992 • 184 citations

Requirement for nerve growth factor in the development of myelinated nociceptors in vivo

1991 • 176 citations

Growth-regulated synthesis and secretion of biologically active nerve growth factor by human keratinocytes.

1991 • 176 citations

Substance P modulates glutamate-induced currents in acutely isolated rat spinal dorsal horn neurones

1990 • 165 citations

Histochemical characterization of sensory neurons with high-affinity receptors for nerve growth factor

1989 • 165 citations

Does neurogenic inflammation alter the sensitivity of unmyelinated nociceptors in the rat?

1986 • 160 citations

On the role of nerve growth factor in the development of myelinated nociceptors

1992 • 146 citations

Nerve growth factor induces mast cell degranulation without changing intracellular calcium levels

1986 • 142 citations

Enhanced release of immunoreactive CGRP and substance P from spinal dorsal horn slices occurs during carrageenan inflammation

1992 • 140 citations

Small diameter myelinated afferents produce vasodilatation but not plasma extravasation in rat skin.

1989 • 125 citations

Storage of 5-Hydroxytryptamine in Rat Mast Cells. Evidence for an Ionic Binding to Carboxyl Groups in a Granule Heparin-Protein Complex

1972 • 125 citations

Somatic and behavioural postnatal effects of fetal injections of nerve growth factor antibodies in the rat

1981 • 125 citations

Dorsal root ganglion neurons expressing trk are selectively sensitive to NGF deprivation in utero

1992 • 123 citations

Modulation of excitatory amino acid responses in rat dorsal horn neurons by tachykinins

1992 • 120 citations

Studies on carrageenan-induced arthritis in adult rats: presence of nerve growth factor and role of sympathetic innervation

1992 • 113 citations

Neuropeptides in physiologically identified mammalian sensory neurones

1985 • 108 citations

Calcitonin gene-related peptide increases in the dorsal root ganglia of adjuvant arthritic rat

1989 • 108 citations

GAP-43 expression in developing cutaneous and muscle nerves in the rat hindlimb

1991 • 104 citations

Release and spread of immunoreactive neurokinin A in the cat spinal cord in a model of acute arthritis

1990 • 83 citations

Synergistic effects of nerve growth factor and granulocyte-macrophage colony-stimulating factor on human basophilic cell differentiation

1991 • 81 citations

Nerve growth factor and the peptidergic sensory neurons

1984 • 63 citations

Regulation of Afferent Connectivity in the Adult Spinal Cord by Nerve Growth Factor

1992 • 59 citations

Evidence for an Increase in the Release of CGRP from Sensory Nerves during Inflammationa

1992 • 43 citations

Neonatal Anti‐NGF Treatment Reduces the Aδ‐ and C‐Fibre Evoked Vasodilator Responses in Rat Skin: Evidence That Nociceptor Afferents Mediate Antidromic Vasodilatation

1992 • 36 citations

Regulation of myelinated nociceptor function by nerve growth factor in neonatal and adult rats

1993 • 33 citations

Differential effects on sensory nerve processes and behavioral alterations in the rat after treatment with antibodies to nerve growth factor

1991 • 30 citations

Perinatal changes in epidermal innervation in rat and mouse

1966 • 29 citations

Isolated hepatic granulomas from mice infected with Schistosoma mansoni contain nerve growth factor

1991 • 25 citations

Long‐Term Increase in CGRP Levels in Rat Spinal Dorsal Horn following Skin Ultraviolet Irradiation

1992 • 15 citations

An epitope on the transferrin receptor preferentially exposed during tumor progression in human lymphoma is close to the ligand binding site

1991 • 6 citations