Isolated congenital ACTH deficiency: a cleavage enzyme defect?

A chimaeric llβ-hydroxylase/aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension

1992 • 1,126 citations

Intraorganellar calcium and pH control proinsulin cleavage in the pancreatic β cell via two distinct site-specific endopeptidases

1988 • 403 citations

Proinsulin processing by the subtilisin-related proprotein convertases furin, PC2, and PC3.

1992 • 300 citations

A member of the eukaryotic subtilisin family (PC3) has the enzymic properties of the type 1 proinsulin-converting endopeptidase

1992 • 123 citations

The cDNA Sequence of the Human Pro-Hormone and Pro-Protein Convertase PC1

1992 • 48 citations

Chromosomal assignments of the genes for neuroendocrine convertase PC1 (NEC1) to human 5q15–21, neuroendocrine convertase PC2 (NEC2) to human 20p11.1–11.2, and furin (mouse 7[D1-E2] region)

1991 • 45 citations

Isolated congenital ACTH deficiency: a cleavage enzyme defect?

1993 • 30 citations