Thrombin-Induced Increase in Endothelial Permeability Is Associated With Changes in Cell-to-Cell Junction Organization

Cadherin Cell Adhesion Receptors as a Morphogenetic Regulator

1991 • 3,314 citations

Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase

1986 • 2,445 citations

Permanent cell line expressing human factor VIII-related antigen established by hybridization.

1983 • 1,458 citations

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions.

1992 • 1,456 citations

From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion

1993 • 997 citations

Beta-catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor.

1994 • 712 citations

A novel endothelial-specific membrane protein is a marker of cell-cell contacts.

1992 • 637 citations

The molecular organization of endothelial cell to cell junctions: differential association of plakoglobin, beta-catenin, and alpha-catenin with vascular endothelial cadherin (VE-cadherin).

1995 • 573 citations

Regulation of endothelial cell gap formation and barrier dysfunction: Role of myosin light chain phosphorylation

1995 • 550 citations

Endothelial cell‐to‐cell junctions

1995 • 481 citations

Cadherins

1992 • 437 citations

Inhibition of protein kinase C by calphostin C is light-dependent

1991 • 374 citations

Diversity of the cadherin family: evidence for eight new cadherins in nervous tissue.

1991 • 363 citations

Molecular linkage between cadherins and actin filaments in cell—cell adherens junctions

1992 • 359 citations

Inhibition of gap junction and adherens junction assembly by connexin and A-CAM antibodies.

1992 • 351 citations

Thrombin‐induced increase in albumin permeability across the endothelium

1986 • 307 citations

The role of integrins in the maintenance of endothelial monolayer integrity.

1991 • 290 citations

Thrombin treatment induces rapid changes in tyrosine phosphorylation in platelets.

1989 • 276 citations

Increased endothelial albumin permeability mediated by protein kinase C activation.

1990 • 271 citations

Endothelioma cells expressing the polyoma middle T oncogene induce hemangiomas by host cell recruitment

1989 • 252 citations

Role of actin and myosin in the control of paracellular permeability in pig, rat and human vascular endothelium.

1990 • 196 citations

Thrombin-induced gap formation in confluent endothelial cell monolayers in vitro

1983 • 164 citations

p120, a p120-related protein (p100), and the cadherin/catenin complex.

1995 • 156 citations

Regulation of permeabilized endothelial cell retraction by myosin phosphorylation

1991 • 149 citations

Mechanism-based inactivation of horseradish peroxidase by sodium azide. Formation of meso-azidoprotoporphyrin IX

1988 • 141 citations

β-catenin: a common target for the regulation of cell adhesion by Wnt-1 and Src signaling pathways

1994 • 118 citations

Thrombin receptor activating peptides induce Ca²⁺ mobilization, barrier dysfunction, prostaglandin synthesis, and platelet‐derived growth factor mRNA expression in cultured endothelium

1993 • 114 citations

Thrombin-Mediated Increase in Vascular Endothelial Permeability

1992 • 97 citations

Cyclic-GMP-Mediated Decrease in Permeability of Human Umbilical and Pulmonary Artery Endothelial Cell Monolayers

1994 • 96 citations

Endothelial cells: adhesion and tight junctions

1992 • 96 citations

Identification and cloning of two species of cadherins in bovine endothelial cells.

1990 • 96 citations

Interaction of human α‐thrombin and γ‐thrombin with antithrombin III, protein C and thrombomodulin

1985 • 85 citations

Towards selective pharmacological modulation of protein kinase C – opportunities for the development of novel antineoplastic agents

1992 • 81 citations

Inhibition of interleukin 3 and granulocyte-macrophage colony-stimulating factor stimulated increase of active ras.GTP by herbimycin A, a specific inhibitor of tyrosine kinases.

1992 • 78 citations

Commentary structure and dynamics of transcriptionally active chromatin

1992 • 65 citations

Evidence that Vascular Endothelial Cells Can Induce the Retraction of Fibrin Clots

1981 • 58 citations

Characterization of an In Vitro Model to Study the Permeability of Human Arterial Endothelial Cell Monolayers

1988 • 57 citations

Signaling Pathways of the Thrombin Receptor

1993 • 51 citations

The Role of Protein Kinase C in α-Thrombin-Mediated Endothelial Cell Activation

1992 • 26 citations

Inflammatory Events after Fibrin Microembolization: Alterations in Alveolar Macrophage and Neutrophil Function

1988 • 20 citations

Evidence for a selective inhibitory effect of thrombin on megakaryocyte progenitor growth mediated by the thrombin receptor

1994 • 17 citations

Regulation of Thrombin-Induced Endothelial Barrier Dysfunction and Prostaglandin Synthesis

1992 • 13 citations

Generation of Human Umbilical Vein Endothelial Cell Lines Which Maintain Their Differentiated Phenotype

1994 • 9 citations