Radiosensitivity testing of primary cervical carcinoma: evaluation of intra- and inter-tumour heterogeneity

Inherent cellular radiosensitivity as a basic concept for human tumor radiotherapy

1981 • 530 citations

Intrinsic radiosensitivity of human cell lines is correlated with radioresponsiveness of human tumors: Analysis of 101 published survival curves

1985 • 488 citations

The radioresponsiveness of human tumours and the initial slope ofthe cell survival curve

1984 • 472 citations

A Critical Appraisal of the Human Tumor Stem-Cell Assay

1983 • 365 citations

An in vitro colony assay for human tumours grown in immune-suppressed mice and treated in vivo with cytotoxic agents

1978 • 296 citations

Differential responses to x-irradiation of subpopulations of two heterogeneous human carcinomas in vitro.

1982 • 104 citations

Radiation sensitivity in vitro of cells isolated from human tumor surgical specimens.

1987 • 84 citations

Therapeutic implications of tumor heterogeneity.

1989 • 83 citations

Radiosensitivity of Human Head and Neck Squamous Cell Carcinomas in Primary Culture and its Potential as a Predictive Assay of Tumor Radiocurability

1989 • 75 citations

Evaluation of Surviving Fraction at 2 Gy as a Potential Prognostic Factor for the Radiotherapy of Carcinoma of the Cervix

1989 • 73 citations

Heterogeneity in growth pattern and drug sensitivity of primary tumor and metastases in the human tumor colony-forming assay.

1982 • 72 citations

The effect, of patient-to-patient variability on the accuracy of predictive assays of tumor response to radiotherapy: A theoretical evaluation

1989 • 65 citations

Quantitation of the number of cells within tumor colonies in semisolid medium and their growth as oblate spheroids.

1984 • 60 citations

Expression of low molecular weight cytokeratin proteins in cervical neoplasia

1986 • 58 citations

Flow cytofluorometric evidence for the differential radioresponsiveness of aneuploid and diploid cervix tumours

1987 • 51 citations

A radiobiological comparison of human tumor soft‐agar clonogenic assays

1986 • 31 citations

Non-linearity of colony formation by human tumour cells from biopsy samples

1985 • 28 citations

The human tumor stem cell assay revisited

1985 • 21 citations

Heterogeneity in radiation sensitivity within human primary tumour cell cultures as detected by the SCE assay

1989 • 20 citations

Clonogenic cell survival in cryopreserved human tumour cells

1981 • 15 citations

Selection of tumour cell subpopulations occurs during cultivation of human tumours in soft agar. A DNA flow cytometric study

1985 • 12 citations

cis-Diamminedichloroplatinum(II)-induced sister chromatid exchange: an indicator of sensitivity and heterogeneity in primary human tumor cell cultures.

1986 • 10 citations

Cellular heterogeneity in human epithelial neoplasms

1988 • 4 citations

Possible relationship between chromosome alterations and radiosensitivity in human malignant melanoma

1989 • 3 citations