Neurofibromin Colocalizes with Mitochondria in Cultured Cells

Localization of mitochondria in living cells with rhodamine 123.

1980 • 1,529 citations

Von Recklinghausen Neurofibromatosis

1981 • 1,336 citations

The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins

1990 • 834 citations

The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae

1990 • 684 citations

Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients

1992 • 648 citations

Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis

1992 • 583 citations

cDNA cloning of the type 1 neurofibromatosis gene: Complete sequence of the NF1 gene product

1991 • 391 citations

Differential regulation of rasGAP and neurofibromatosis gene product activities

1991 • 338 citations

The protein product of the neurofibromatosis type 1 gene is expressed at highest abundance in neurons, Schwann cells, and oligodendrocytes

1992 • 309 citations

Association of mitochondria with microtubules in cultured cells.

1978 • 296 citations

Mitochondria are associated with microtubules and not with intermediate filaments in cultured fibroblasts.

1982 • 262 citations

Bcl-2 associates with the ras-related protein R-rasp23

1993 • 259 citations

Identification and characterization of the neurofibromatosis type 1 protein product.

1991 • 204 citations

Visualization of a system of filaments 7-10 nm thick in cultured cells of an epithelioid line (Pt K2) by immunofluorescence microscopy.

1977 • 176 citations

Biochemically Differentiated Neoplastic Clone of Schwann Cells

1972 • 165 citations

Loss of neurofibromin results in neurotrophin-independent survival of embryonic sensory and sympathetic neurons

1995 • 158 citations

R-Ras promotes apoptosis caused by growth factor deprivation via a Bcl-2 suppressible mechanism.

1995 • 142 citations

Neurofibromatosis type 1 gene product (neurofibromin) associates with microtubules

1993 • 140 citations

bcl‐2, a novel reguator of cell death

1995 • 128 citations

Neurofibromatosis Type 1: Pathology, Clinical Features and Molecular Genetics

1995 • 108 citations

Primary biliary cirrhosis and mitochondrial autoantigens—insights from molecular biology

1988 • 99 citations

Modulation of hexokinase association with mitochondria analyzed with quantitative three-dimensional confocal microscopy.

1991 • 84 citations

Interrelationships of endoplasmic reticulum, mitochondria, intermediate filaments, and microtubules—a quadruple fluorescence labeling study

1992 • 79 citations

Neurofibromin is enriched in the endoplasmic reticulum of CNS neurons

1993 • 79 citations

Shc Proteins Are Localized on Endoplasmic Reticulum Membranes and Are Redistributed after Tyrosine Kinase Receptor Activation

1996 • 74 citations

Rapid Purification of Mitochondrial Hexokinase from Rat Brain by a Single Affinity Chromatography Step on Affi-Gel Blue

1989 • 69 citations

Protein disulphide-isomerase from human placenta and rat liver. Purification and immunological characterization with monoclonal antibodies

1987 • 67 citations

[5] Preparation of bovine heart mitochondria in high yield

1979 • 60 citations

Catalytic properties, tissue and intracellular distribution of neurofibromin.

1992 • 56 citations

Recent progress toward understanding the molecular biology of von Recklinghausen neurofibromatosis

1992 • 51 citations

Identification of neurofibromatosis type I gene product as an insoluble GTPase-activating protein toward ras p21.

1992 • 40 citations

Establishment and characterization of a human leptomeningeal cell line

1991 • 33 citations

Characterization of adult human astrocytes derived from explant culture

1990 • 29 citations

Incidence, types, and management of cancer in patients with neurofibromatosis.

1989 • 24 citations

Subsurface and cytoplasmic cisterns associated with mitochondria in pyramidal neurons of the rat dorsal cochlear nucleus

1981 • 21 citations

Identification of a GTP-binding protein in the contact sites between inner and outer mitochondrial membranes

1991 • 20 citations

Reduced Expression of Neurofibromin in the Soft Tissue Tumours Obtained from Patients with Neurofibromatosis Type 1

1995 • 16 citations

p21 ras proteins and guanine nucleotides modulate the phosphorylation of 36- and 17-kilodalton mitochondria-associated proteins.

1986 • 12 citations

Effects of antimitotic and antimitochondrial agents on the cellular distribution of microtubules and mitochondria.

1990 • 7 citations