Dissection of NADPH-cytochrome P450 oxidoreductase into distinct functional domains.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

1991 • 2,371 citations

Ethoxyresorufin: direct fluorimetric assay of a microsomal O-dealkylation which is preferentially inducible by 3-methylcholanthrene.

1974 • 1,562 citations

Some properties of a detergent-solubilized NADPH-cytochrome c(cytochrome P-450) reductase purified by biospecific affinity chromatography.

1976 • 1,180 citations

Microsomal Triphosphopyridine Nucleotide-Cytochrome c Reductase of Liver

1962 • 909 citations

Nitric oxide synthase regulatory sites. Phosphorylation by cyclic AMP-dependent protein kinase, protein kinase C, and calcium/calmodulin protein kinase; identification of flavin and calmodulin binding sites.

1992 • 621 citations

Atomic Structure of Ferredoxin-NADP ⁺ Reductase: Prototype for a Structurally Novel Flavoenzyme Family

1991 • 532 citations

Genomic organization of the human oestrogen receptor gene.

1988 • 480 citations

A new method for preparing flavin-adenine dinucleotide

1953 • 474 citations

Purified liver microsomal NADPH-cytochrome P-450 reductase. Spectral characterization of oxidation-reduction states.

1978 • 346 citations

Properties of hepatic reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase

1973 • 344 citations

Separate roles for FMN and FAD in catalysis by liver microsomal NADPH-cytochrome P-450 reductase.

1981 • 295 citations

Structural analysis of the FMN binding domain of NADPH-cytochrome P-450 oxidoreductase by site-directed mutagenesis

1989 • 261 citations

Immunochemical Evidence for an Association of Heme Oxygenase with the Microsomal Electron Transport System

1972 • 250 citations

NADPH-cytochrome P-450 oxidoreductase: flavin mononucleotide and flavin adenine dinucleotide domains evolved from different flavoproteins

1986 • 241 citations

Identification of the high and low potential flavins of liver microsomal NADPH-cytochrome P-450 reductase.

1978 • 238 citations

Cytochrome b5 reduction by NADPH-cytochrome P-450 reductase.

1979 • 199 citations

Role of NADPH:cytochrome c reductase and DT-diaphorase in the biotransformation of mitomycin C1.

1984 • 178 citations

Coding nucleotide sequence of rat NADPH-cytochrome P-450 oxidoreductase cDNA and identification of flavin-binding domains.

1985 • 171 citations

Calcium/calmodulin-dependent nitric oxide synthase type I: a biopteroflavoprotein with calcium/calmodulin-independent diaphorase and reductase activities

1992 • 151 citations

Characterization of the Flavoprotein Moieties of NADPH-Sulfite Reductase from Salmonella typhimurium and Escherichia coli

1989 • 149 citations

Oxidation-reduction states of FMN and FAD in NADPH-cytochrome P-450 reductase during reduction by NADPH.

1982 • 143 citations

Role of a hydrophobic polypeptide in the N-terminal region of NADPH-cytochrome P-450 reductase in complex formation with P-450lm

1979 • 113 citations

Microsomal lipid peroxidation: The role of NADPH — Cytochrome P450 reductase and cytochrome P450

1990 • 103 citations

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

1991 • 94 citations

Studies on the microsomal mixed-function oxidase system: mechanism of action of hepatic NADPH-cytochrome P-450 reductase

1981 • 88 citations

NADPH-cytochrome P-450 oxidoreductase gene organization correlates with structural domains of the protein

1990 • 83 citations

The role of cytochrome P450 and cytochrome P450 reductase in the reductive bioactivation of the novel benzotriazine di-N-oxide hypoxic cytotoxin 3-amino-l,2,4-benzotriazine-l ,4-dioxide (SR 4233, WIN 59075) by mouse liver

1992 • 78 citations

Localization of cytochrome c-binding domain on NADPH-cytochrome P-450 reductase.

1986 • 77 citations

Evidence for a new physiological role of hepatic NADPH:ferricytochrome (P-450) oxidoreductase. Direct electron input to the microsomal fatty acid chain elongation system.

1981 • 75 citations

Intron Existence Predated the Divergence of Eukaryotes and Prokaryotes

1988 • 55 citations

Identification and characterization of an NADPH-cytochrome P450 reductase derived peptide involved in binding to cytochrome P450

1991 • 54 citations

Quantification of cytochrome P450 reductase gene expression in human tissues

1992 • 46 citations

NADPH-cytochrome P-450 reductase. Physical properties and redox behavior in the absence of the FAD moiety.

1990 • 33 citations