DNA, RNA and protein interactions

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

On the nature of allosteric transitions: A plausible model

1965 • 8,699 citations

Genetic regulatory mechanisms in the synthesis of proteins

1961 • 6,378 citations

Computed circular dichroism spectra for the evaluation of protein conformation

1969 • 3,654 citations

Repeated Sequences in DNA

1968 • 2,836 citations

Sedimentation studies of the size and shape of DNA

1965 • 2,189 citations

Viral RNA-dependent DNA Polymerase: RNA-dependent DNA Polymerase in Virions of Rous Sarcoma Virus

1970 • 2,061 citations

Gene Regulation for Higher Cells: A Theory

1969 • 2,022 citations

Viral RNA-dependent DNA Polymerase: RNA-dependent DNA Polymerase in Virions of RNA Tumour Viruses

1970 • 1,992 citations

FORMATION AND DETECTION OF RNA-DNA HYBRID MOLECULES IN CYTOLOGICAL PREPARATIONS

1969 • 1,214 citations

Factor Stimulating Transcription by RNA Polymerase

1969 • 983 citations

A Restriction enzyme from Hemophilus influenzae

1970 • 859 citations

Studies of the binding of actinomycin and related compounds to DNA

1968 • 842 citations

Termination Factor for RNA Synthesis

1969 • 801 citations

lac repressor-operator interaction

1970 • 791 citations

Consideration of the Hydrodynamic Properties of Proteins^1,2

1953 • 725 citations

Lac represser-operator interaction

1973 • 699 citations

ISOLATION OF THE LAC REPRESSOR

1966 • 657 citations

Polypeptide Chain Initiation: Nucleotide Sequences of the Three Ribosomal Binding Sites in Bacteriophage R17 RNA

1969 • 640 citations

DNA Modification and Restriction

1969 • 624 citations

RECONSTITUTION OF ACTIVE TOBACCO MOSAIC VIRUS FROM ITS INACTIVE PROTEIN AND NUCLEIC ACID COMPONENTS

1955 • 613 citations

A restriction enzyme from Hemophilus influenzae

1970 • 592 citations

Organ-specific restriction of transcription in mammalian chromatin

1968 • 556 citations

New RNA Polymerase from Escherichia coli infected with Bacteriophage T7

1970 • 534 citations

Assembly Mapping of 30S Ribosomal Proteins from E. coli

1970 • 524 citations

The isolation and properties of deoxyribonucleoprotein particles containing single nucleic acid molecules

1959 • 484 citations

Chromosomal and Nuclear Location of Mouse Satellite DNA in Individual Cells

1970 • 470 citations

Identification and Functional Characterization of the Protein controlled by the Streptomycin-resistant Locus in E. coli

1969 • 461 citations

A restriction enzyme from Hemophilus influenzae: II. Base sequence of the recognition site

1970 • 455 citations

The Biology of Isolated Chromatin

1968 • 450 citations

A Deoxyribonucleic Acid Polymerase from Micrococcus luteus (Micrococcus lysodeikticus) Isolated on Deoxyribonucleic Acid-Cellulose

1968 • 433 citations

Calf and Pea Histone IV

1969 • 393 citations

Heterogeneity of histones. I. A quantitative analysis of calf histones in very long polyacrylamide gels

1969 • 393 citations

Selective dissociation of histones from calf thymus nucleoprotein

1967 • 392 citations

Cyclic Re-use of the RNA Polymerase Sigma Factor

1969 • 392 citations

Ribonucleic Acid Synthesis of Vesicular Stomatitis Virus, II. An RNA Polymerase in the Virion

1970 • 369 citations

Base Sequence and Evolution of Guinea-pig α-Satellite DNA

1970 • 357 citations

Mutants that make more lac repressor.

1968 • 354 citations

Sequence-specific interaction of DNA and chromosomal protein

1969 • 337 citations

[96] Isolation and characterization of chromosomal nucleoproteins

1968 • 328 citations

Chemical studies on methionyl-tRNA synthetase from Escherichia coli

1970 • 317 citations

The lac operator is DNA.

1967 • 303 citations

Characterization of the Products of RNA-directed DNA Polymerases in Oncogenic RNA Viruses

1970 • 292 citations

Poxvirus DNA-dependent RNA polymerase.

1967 • 292 citations

Structure and function of Escherichia coli ribosomes

1969 • 292 citations

Structure and Synthesis of Ribosomal RNA

1970 • 289 citations

ISOLATION OF THE λ PHAGE REPRESSOR

1967 • 285 citations

ENZYMATIC INCORPORATION OF RIBONUCLEOSIDE TRIPHOSPHATES INTO THE INTERPOLYNUCLEOTIDE LINKAGES OF RIBONUCLEIC ACID

1960 • 279 citations

lac repressor—Operator interaction

1970 • 279 citations

Initiation of Haemoglobin Synthesis by Methionyl-tRNA

1970 • 278 citations

Limited heterogeneity of the major nonhistone chromosomal proteins

1970 • 271 citations

Effect of protein-bound RNA associated with chick embryo chromatin on template specificity of the chromatin

1969 • 267 citations

Total Synthesis of the Gene for an Alanine Transfer Ribonucleic Acid from Yeast

1970 • 262 citations

Specific Binding of the λ Phage Repressor to λ DNA

1967 • 254 citations

Morphogenesis of bacteriophage T4 in extracts of mutant-infected cells.

1966 • 250 citations

Enzyme from Calf Thymus Degrading the RNA Moiety of DNA-RNA Hybrids: Effect on DNA-Dependent RNA Polymerase

1969 • 249 citations

Control by Estrogen of Genetic Transcription and Translation

1968 • 249 citations

Physical and biological properties of soluble nucleohistones

1964 • 244 citations

Secondary structure of bacteriophage f2 ribonucleic acid and the initiation of in vitro protein biosynthesis

1970 • 235 citations

Rifampicin Sensitivity of the Components of DNA-dependent RNA Polymerase

1969 • 235 citations

Initiation of DNA‐Dependent RNA Synthesis and the Effect of Heparin on RNA Polymerase

1967 • 233 citations

Drugs which affect the Structure and Function of DNA

1968 • 229 citations

Mechanism of Antibody Diversity: Germ Line Basis for Variability

1970 • 222 citations

The binding of RNA polymerase to DNA

1966 • 218 citations

RNA polymerase activity in purified reoviruses.

1968 • 218 citations

Some properties of the single strands isolated from the DNA of the nuclear satellite of the mouse (Mus musculus)

1969 • 213 citations

Transfer Ribonucleic Acids

1969 • 209 citations

RNA polymerase activity in purified infectious vaccinia virus.

1967 • 206 citations

Histones and Other Nuclear Proteins

1965 • 205 citations

Circular dichroism of polynucleotides: A simple theory

1969 • 199 citations

Further fractionations of histones from calf thymus

1962 • 197 citations

Isolation of Pure lac Operon DNA*

1969 • 195 citations

Fractionation of the complementary strands of coliphage λ DNA based on the asymmetric distribution of the poly I,G-binding sites

1967 • 193 citations

Influence of Salts on RNA Synthesis by DNA-Dependent RNA-Polymerase from Escherichia coli

1967 • 193 citations

Chromosomal Proteins

1969 • 192 citations

Ribonucleases

1969 • 191 citations

Super-helical Model for Nucleohistone

1967 • 189 citations

Qualitative Species Differences and Quantitative Tissue Differences in the Distribution of Lysine-rich Histones

1969 • 188 citations

T7-directed protein synthesis

1969 • 187 citations

Recognition of tRNA by isoleucyl-tRNA synthetase

1969 • 186 citations

Change in the Template Specificity of RNA Polymerase during Sporulation of Bacillus subtilis

1969 • 184 citations

Assembly of phage lambda in vitro.

1966 • 182 citations

The Specificity of Molecular Hybridization Reactions

1970 • 182 citations

On the assay, isolation and characterization of the lac repressor

1968 • 181 citations

Description of two procedures which avoid the use of extreme pH conditions for the resolution of components isolated from chromatins prepared from pig cerebellar and pituitary nuclei

1970 • 179 citations

Thermal denaturation and template properties of DNA complexes with purified histone fractions

1970 • 175 citations

Nucleotide Sequence from the Polypeptide Chain Termination Region of the Coat Protein Cistron in Bacteriophage R17 RNA

1970 • 171 citations

Amino-acid Sequence of Slightly Lysine-rich Histone

1970 • 170 citations

Mechanism of RNA polymerase action: Characterization of the DNA-dependent synthesis of polyadenylic acid

1964 • 168 citations

On the Similarity of Plant and Animal Histones^*

1966 • 167 citations

Proteins of the Cell Nucleus

1967 • 163 citations

Cell and molecular biology

1968 • 163 citations

Interaction of histone half-molecules with deoxyribonucleic acid

1971 • 162 citations

Physical studies of ribosomes from Escherichia coli

1969 • 161 citations

Structural Alteration of RNA Polymerase during Sporulation

1970 • 159 citations

The Isolation, Properties, and Possible Functions of Chromatin Acidic Proteins

1967 • 157 citations

Structural Analysis of the Glycine-rich, Arginine-rich Histone

1969 • 157 citations

Circular dichrosim of calf liver nucleohistone

1970 • 157 citations

Histone-bound RNA, a component of native nucleohistone.

1965 • 156 citations

Cyclic dissociation into stable subunits and re-formation of ribosomes during bacterial growth

1968 • 155 citations

INHIBITION OF DNA-DEPENDENT RNA SYNTHESIS BY RIFAMYCINS

1968 • 155 citations

Biochemistry of Cell Division

1970 • 152 citations

Hybrid 30S Ribosomal Particles reconstituted from Components of Different Bacterial Origins

1968 • 151 citations

Nucleotide Sequences from Specific Areas of the 16S and 23S Ribosomal RNAs of E. coli

1969 • 151 citations

A rifampicin resistent rna‐polymerase from E. coli altered in the β‐subunit

1969 • 150 citations

Enzymes in DNA Metabolism

1969 • 149 citations

The Function of Pseudouridylic Acid in Transfer Ribonucleic Acid

1969 • 149 citations

On the Complexity of Calf Thymus Histone^*

1962 • 147 citations

Sequence of the First 175 Nucleotides from the 5′ Terminus of Qβ RNA synthesized in vitro

1969 • 146 citations

The assembly in vitro of some small spherical viruses, hybrid viruses, and other nucleoproteins

1968 • 145 citations

Interaction of poly-l-lysine and nucleic acids

1966 • 143 citations

Terminal repetition in non-permuted T3 and T7 bacteriophage DNA molecules

1967 • 142 citations

E. coli σ Factor: A Positive Control Element in Phage T4 Development

1969 • 141 citations

The operators controlled by the lambda phage repressor.

1968 • 139 citations

Initiation of RNA Synthesis: the Function of σ in the Binding of RNA Polymerase to Promoter Sites

1970 • 138 citations

Bacteriophage Sigma Factor for RNA Polymerase

1969 • 135 citations

Role of a protein factor in the functional binding of ribosomes to natural messenger RNA

1968 • 131 citations

Interaction of lysine-rich histones and DNA

1969 • 127 citations

in vitro MORPHOGENESIS OF PHAGE P22 FROM HEADS AND BASE-PLATE PARTS

1967 • 127 citations

RNA synthesis in Escherichia coli after irradiation with ultraviolet light

1969 • 126 citations

Studies on Methionyl Transfer RNA Synthetase

1968 • 125 citations

Observations on Flea Transfer between Hosts; a Mechanism in the Spread of Bubonic Plague

1958 • 123 citations

Cell Growth and Division

1969 • 122 citations

Ribonucleoprotein complexes formed between bacteriophage MS2 RNA and MS2 Protein in vitro

1967 • 121 citations

Optical absorbance and optical rotatory dispersion studies on calf thymus nucleohistone

1969 • 120 citations

The promoter-operator region of the Lac operon of Escherichia coli

1968 • 119 citations

Conformation of deoxyribonucleic acid in chromatin: A circular dichroism study

1970 • 119 citations

The process of infection with coliphage T7

1969 • 118 citations

Evidence for a Single-Stranded Adenovirus-Associated Virus Genome: Isolation and Separation of Complementary Single Strands

1970 • 117 citations

Breaks in DNA stimulate Transcription by Core RNA Polymerase

1969 • 116 citations

Bacteriophage T4 head morphogenesis

1971 • 115 citations

Structure of tomato bushy stunt virus

1969 • 115 citations

Binding of basic proteins to DNA

1965 • 113 citations

The Eukaryotic Chromosome

1970 • 112 citations

Control of Template Specificity of E. coli RNA Polymerase by a Phage-coded Protein

1969 • 110 citations

Immunoglobulin Structure: Variability and Homology

1969 • 107 citations

Recombination of DNA Molecules

1966 • 107 citations

Studies on valyl-tRNA synthetase and tRNAVal from Escherichia coli,

1969 • 106 citations

Recognition of Nucleotide Sequences

1969 • 106 citations

Binding of actinomycin D to calf thymus chromatin

1971 • 103 citations

Messenger RNA

1969 • 103 citations

An Investigation of the Conformational Changes of Histones F1 and F2a₁ by Proton Magnetic Resonance Spectroscopy

1970 • 101 citations

ENZYMATIC REPAIR OF DNA, I. PURIFICATION OF TWO ENZYMES INVOLVED IN THE EXCISION OF THYMINE DIMERS FROM ULTRAVIOLET-IRRADIATED DNA

1969 • 101 citations

Enzymatic Synthesis of Deoxyribonucleic Acid

1969 • 98 citations

The Methylation of Lysine Residues in Protein

1966 • 95 citations

Sub-unit structure and specificity of methionyl-transfer-ribonucleic acid synthetase from Escherichia coli

1968 • 92 citations

STUDIES ON THE RIBONUCLEIC ACID POLYMERASE FROM ESCHERICHIA COLI. I. PURIFICATION OF THE ENZYME AND STUDIES OF RIBONUCLEIC ACID FORMATION.

1964 • 92 citations

Transcriptional controls in developing bacteriophages

1969 • 91 citations

Involvement of a Phage T4 σ Factor and an Anti-terminator Protein in the Transcription of Early T4 Genes in vivo

1970 • 87 citations

Spectroscopic studies of the conformations of histones and protamine

1967 • 87 citations

The reconstitution of infective bacteriophage R17.

1967 • 87 citations

Gene Order in the Bacteriophage R17 RNA : 5′–;A Protein–Coat Protein–Synthetase–3′

1970 • 86 citations

Histones and Other Nuclear Proteins.

1966 • 86 citations

The Specificity of Molecular Hybridization in Relation to Studies on Higher Organisms

1969 • 85 citations

Specificity of the Interactions Between Histones and Deoxyribonucleic Acid

1964 • 85 citations

PROTEIN CHAIN INITIATION IN RABBIT RETICULOCYTES

1970 • 85 citations

Requirement of sulfhydryl groups for the catalytic and tRNA recognition functions of isoleucyl-tRNA synthetase

1969 • 84 citations

Untranslated Nucleotide Sequence at the 5′-End of R 17 Bacteriophage RNA

1970 • 84 citations

Prolyl Transfer Ribonucleic Acid Synthetase of Escherichia coli

1969 • 83 citations

Studies of the Ribonucleic Acid Polymerase from Escherichia coli

1964 • 83 citations

Ribosome Formation and Structure

1968 • 82 citations

Regulation of nucleic acid and protein biosyntheis

1967 • 80 citations

Conformational Investigations of Histones

1965 • 78 citations

Chromosomal ribonucleic acid of rat ascites cells

1969 • 77 citations

A Study of the Multiplicity of Lysine-rich Histones

1969 • 77 citations

Ribosome Structure and Function Emergent

1970 • 76 citations

RNA Polymerase and the Control of RNA Synthesis

1969 • 76 citations

Active Form of Two Coliphage Repressors

1970 • 76 citations

Recent investigations on histones and their functions

1968 • 74 citations

Characterization of sea urchin sperm chromatin and its basic proteins

1969 • 72 citations

ISOLATION OF METAPHASE CHROMOSOMES FROM HELA CELLS

1966 • 71 citations

The Nucleotide Sequence of N-Formyl-Methionyl-Transfer RNA. Products of Complete Digestion with Ribonuclease T1 and Pancreatic Ribonuclease and Derivation of their Sequences

1969 • 69 citations

Formation of defective bacteriophage particles by fr amber mutants

1966 • 69 citations

Purification and Properties of Seryl Transfer Ribonucleic Acid Synthetase from Escherichia coli

1970 • 67 citations

Purification of Leucyl Transfer Ribonucleic Acid Synthetase from Escherichia coli

1970 • 63 citations

Structural Studies on Transfer RNA: The Molecular Conformation in Solution

1969 • 62 citations

Conformation of Polypeptide Chains

1969 • 62 citations

Relationships Between Bactericidal Effect and Inhibition of Ribonucleic Acid Nucleotidyl-transferase by Rifampicin in Escherichia coli K-12

1969 • 61 citations

Stepwise removal of histones from native deoxyribonucleoprotein by titration with acid at low temperature and some properties of the resulting partial nucleoproteins

1969 • 60 citations

Isoleucyl Transfer Ribonucleic Acid Synthetase Is a Single Polypeptide Chain

1970 • 59 citations

The Role of Deoxyribonucleic Acid in Ribonucleic Acid Synthesis

1969 • 59 citations

Role of RNA in the assembly process of bacteriophage fr

1969 • 54 citations

Reinitiation of RNA Chain Synthesis in vitro

1970 • 54 citations

CONTROL OF GENE EXPRESSION

1969 • 52 citations

A DNA-RNA complex as an intermediate of in vitro genetic transcription.

1965 • 51 citations

Sheep Kidney Nuclease

1967 • 51 citations

Release Factors mediating Termination of Complete Proteins

1970 • 49 citations

Proton Magnetic Resonance Studies of the Interactions of Histones F1 and F2B with DNA

1971 • 48 citations

The specificity of histones in nucleated erythrocytes

1968 • 48 citations

Selfassembly of Defective Particles of the Bacteriophage fr

1967 • 48 citations

Capacity of T4 DNA to serve as template for purified Escherichia coli RNA polymerase

1966 • 47 citations

Isolation of Chromatin-free RNA Polymerase from Mammalian Cell Nuclei

1968 • 46 citations

Role of RNA Polymerase Stimulating Factor on Chain Initiation

1969 • 45 citations

Micro-analysis of pure deoxyribonucleic acid-dependent ribonucleic acid polymerase from Escherichia coli. Action of heparin and rifampicin on structure and function

1970 • 44 citations

Release Factor Translation of RNA Phage Terminator Codons

1970 • 42 citations

Isolation and some properties of methionine transfer ribonucleic acid from Escherichia coli

1970 • 41 citations

The structures of turnip crinkle and tomato bushy stunt viruses

1970 • 41 citations

The Methylation of the Histones of Rat Liver Nucleiin vitro

1967 • 41 citations

Translation of Phage Qβ mRNA: A Test of the Two-site Model for Ribosomal Function

1970 • 40 citations

Endonuclease from Micrococcus luteus Which Has Activity Toward Ultraviolet-Irradiated Deoxyribonucleic Acid: Its Action on Transforming Deoxyribonucleic Acid

1970 • 39 citations

The assembly of ribosomes

1969 • 39 citations

Histones and Gene Control

1970 • 39 citations

Promoter Mutation in vitro

1969 • 38 citations

Polymerization-Depolymerization of Tobacco Mosaic Virus Protein. VII. A Model^*

1966 • 38 citations

Trout-liver histones

1966 • 37 citations

Conformational change of tyrosyl-RNA synthetase induced by its specific transfer RNA

1967 • 35 citations

The S1 Factor in Peptide Chain Elongation

1970 • 34 citations

TRANSFER RNA, III. RECONSTITUTION OF ALANINE ACCEPTOR ACTIVITY FROM FRAGMENTS PRODUCED BY SPECIFIC CLEAVAGE OF tRNA ^Ala _II AT ITS ANTICODON

1969 • 34 citations

HYBRIDIZATION OF CHROMOSOMAL RNA TO NATIVE DNA

1969 • 33 citations

The self-assembly of spherical viruses with mixed coat proteins

1968 • 32 citations

Reconstitution of infective bacteriophage Qβ

1969 • 32 citations

Induced Activation of Amino Acid Activating Enzymes by Amino Acids and †RNA

1970 • 32 citations

An RNA-histone complex in mammalian cells: the isolation and characterization of a new RNA species.

1966 • 31 citations

The structure of metaphase chromosomes

1970 • 30 citations

Partial Purification of a DNA-polymerase from the Non-histone Chromatin Proteins of Rat Liver

1967 • 29 citations

Further studies of DNA-nucleoprotein gels and residual protein of isolated cell nuclei

1968 • 29 citations

Initiation of protein synthesis,I. Effect of formylation of methionyl-tRNA on codon recognition.

1966 • 28 citations

Assymetry in the distribution of basic amino acid residues in the moderately lysine-rich histone F2b from calf thymus

1970 • 25 citations

Temperature sensitive mutations affecting RNA synthesis in Escherichia coli

1968 • 24 citations

Isolation of a terminal DNA-nucleotidyl transferase from calf thymus non histone chromatin proteins

1968 • 23 citations

Reconstitution of nucleohistone from homologous and heterologous components

1968 • 22 citations

Structural Studies on Transfer RNA: Preliminary Crystallographic Analysis

1969 • 22 citations

The applicability of extraction by trichloroacetic acid to the preparation of very lysine rich histones from the mammary gland

1968 • 20 citations

Structure of the ribosome

1969 • 18 citations

Nucleic Acid-Protein Interactions in Turnip Yellow Mosaic Virus

1969 • 17 citations

Aminoacyl formylmethionyl transfer ribonucleic acid transformylase. Inhibitor studies and the reversal of the reaction

1970 • 16 citations

DNA dependent RNA polymerase from vegetative cells and from spores of B.Subtilis: III. Isolation of a stimulating factor

1969 • 16 citations

A Factor promoting Dissociation of Escherichia coli Ribosomes

1970 • 16 citations

Ribonucleic Acid Polymerase from Micrococcus luteus

1969 • 13 citations

Countercurrent-distribution studies on histones

1967 • 12 citations

Transcription of the Bacteriophage T4 Template: Strand Selection by E. coli RNA Polymerase in vitro

1969 • 11 citations

Synthèse du poly U par la RNA polymérase avec l'acide octoadénylique (hepta adénylyl‐(3′,5′)‐adénosine) comme matrice

1967 • 9 citations

Quantitative Radiation Effects in Hemoproteins and their Constituents

1970 • 8 citations

Studies on binding of RNA polymerase to DNA

1969 • 8 citations

Replication of the RNA genome

1969 • 7 citations

Degradation of RNA Polymerase in E8cherichia coli*

1967 • 6 citations

Recent developments in biochemistry

1968 • 4 citations