Menopause, oestrogens and arthritis

Sex hormones, immune responses, and autoimmune diseases. Mechanisms of sex hormone action.

1985 • 816 citations

The incidence and natural history of knee osteoarthritis in the elderly, the framingham osteoarthritis study

1995 • 710 citations

Osteo-Arthrosis: Prevalence in the Population and Relationship between Symptoms andX-ray Changes

1966 • 694 citations

Regulation of the Immune System by Sex Steroids*

1984 • 668 citations

Effect of castration and sex hormone treatment on survival, anti-nucleic acid antibodies, and glomerulonephritis in NZB/NZW F1 mice.

1978 • 637 citations

Risk factors for coronary artery disease in patients with systemic lupus erythematosus

1992 • 625 citations

Carpal tunnel syndrome in Rochester, Minnesota, 1961 to 1980

1988 • 477 citations

Generalized Osteoarthritis and Heberden's Nodes

1952 • 452 citations

Low-fat diet in myocardial infarction: A controlled trial.

1965 • 437 citations

Frequency of lupus flare in pregnancy: The hopkins lupus pregnancy center experience

1991 • 396 citations

Incidence and risk factors for radiographic knee osteoarthritis in middle-aged women: The Chingford Study

1999 • 395 citations

"Menopausal Symptoms" in Women of Various Ages

1965 • 382 citations

IL-6 production by human articular chondrocytes. Modulation of its synthesis by cytokines, growth factors, and hormones in vitro.

1990 • 361 citations

Rheumatism in populations

1977 • 297 citations

Low plasma androgens in women with systemic lupus erythematosus

1987 • 286 citations

Dehydroepiandrosterone enhances IL2 production and cytotoxic effector function of human T cells

1991 • 275 citations

Pathogenesis of osteoarthritis

1986 • 272 citations

Prolactin Release During Nursing and Breast Stimulation in Postpartum and Nonpostpartum Subjects¹

1974 • 256 citations

Lupus and pregnancy studies

1993 • 255 citations

Rheumatism in Populations

1977 • 254 citations

Regulation of the immune response by sex hormones. I. In vitro effects of estradiol and testosterone on pokeweed mitogen-induced human B cell differentiation.

1988 • 242 citations

Timing of Pregnancy in Relation to the Onset of Rheumatoid Arthritis

1992 • 239 citations

Androgen replacement therapy in male patients with rheumatoid arthritis

1991 • 213 citations

Increased 16α-Hydroxylation of Estradiol in Systemic Lupus Erythematosus*

1981 • 208 citations

Postmenopausal Estrogen Therapy and the Risk for Developing Systemic Lupus Erythematosus

1995 • 203 citations

Association of estrogen replacement therapy with the risk of osteoarthritis of the hip in elderly white women. Study of Osteoporotic Fractures Research Group.

1996 • 193 citations

Is hormone replacement therapy protective for hand and knee osteoarthritis in women?: The Chingford study

1997 • 189 citations

Estrogen replacement therapy and worsening of radiographic knee osteoarthritis: The Framingham study

1998 • 182 citations

Estrogen enhancement of anti–double‐stranded DNA antibody and immunoglobulin G production in peripheral blood mononuclear cells from patients with systemic lupus erythematosus

1999 • 169 citations

Pregnancy does not cause systemic lupus erythematosus to worsen

1989 • 168 citations

An open study of dehydroepiandrosterone in systemic lupus erythematosus

1994 • 166 citations

Oestrogen and Human T Lymphocytes: Presence of Specific Receptors in the T‐Suppressor/Cytotoxic Subset

1988 • 164 citations

Osteoarthrosis of the knee in men and women in association with overweight, smoking, and hormone therapy

1999 • 164 citations

Reproductive Factors, Smoking, and the Risk for Rheumatoid Arthritis

1990 • 164 citations

Nonoccupational risk factors for carpal tunnel syndrome

1999 • 162 citations

Onset of symptoms of rheumatoid arthritis in relation to age, sex and menopausal transition.

1990 • 160 citations

Estrogen use and radiographic osteoarthritis of the knee in women

1990 • 157 citations

Breast‐feeding and the onset of rheumatoid arthritis

1994 • 152 citations

Association of Bone Mineral Density and Sex Hormone Levels with Osteoarthritis of the Hand and Knee in Premenopausal Women

1996 • 147 citations

A double-blind, placebo-controlled, clinical trial of dehydroepiandrosterone in severe systemic lupus erythematosus

1999 • 146 citations

Sex hormone status and osteoporosis in postmenopausal women with rheumatoid arthritis

1988 • 142 citations

Hypothalamic-pituitary-adrenocortical axis function in premenopausal women with rheumatoid arthritis not treated with glucocorticoids.

1999 • 140 citations

Estrogen enhancement of anti-double-stranded DNA antibody and immunoglobulin G production in peripheral blood mononuclear cells from patients with systemic lupus erythematosus

1999 • 140 citations

Female sex hormones suppress development of collagen‐induced arthritis in mice

1986 • 138 citations

IS OSTEOARTHRITIS IN WOMEN AFFECTED BY HORMONAL CHANGES OR SMOKING?

1993 • 137 citations

Long term use of megestrol acetate by cancer survivors for the treatment of hot flashes.

1998 • 135 citations

In vitro potentiation of lymphocyte activation by dehydroepiandrosterone, androstenediol, and androstenetriol.

1994 • 133 citations

Treatment of systemic lupus erythematosus with dehydroepiandrosterone: 50 patients treated up to 12 months.

1998 • 129 citations

Prolactin, immunoregulation, and autoimmune diseases

1991 • 126 citations

Oral contraceptives and rheumatoid arthritis: Results from a primary care-based incident case-control study

1997 • 124 citations

Oral contraception, parity, breast feeding, and severity of rheumatoid arthritis.

1996 • 119 citations

Oral contraceptives and systemic lupus erythematosus

1997 • 118 citations

Low plasma androgens in women with active or quiescent systemic lupus erythematosus

1982 • 117 citations

Onset of symptoms of rheumatoid arthritis in relation to age, sex and menopausal transition

1991 • 115 citations

Noncontraceptive Hormones and Rheumatoid Arthritis in Perimenopausal and Postmenopausal Women

1986 • 113 citations

Risk factors for osteoarthritis in the tibiofemoral and patellofemoral joints of the knee.

1997 • 108 citations

Estradiol enhances binding to cultured human keratinocytes of antibodies specific for SS-A/Ro and SS-B/La. Another possible mechanism for estradiol influence of lupus erythematosus.

1988 • 107 citations

Generalized osteoarthritis in women: pattern of joint involvement and approaches to definition for epidemiological studies.

1996 • 107 citations

Adrenal and gonadal steroid hormone deficiency in the pathogenesis of rheumatoid arthritis.

1996 • 104 citations

Long term use of megestrol acetate by cancer survivors for the treatment of hot flashes

1998 • 104 citations

Biochemical effects of estrogen on articular cartilage in ovariectomized sheep

1997 • 104 citations

Sex hormones and the risk of osteoarthritis in women: epidemiological evidence.

1996 • 97 citations

Androgens as adjuvant treatment in postmenopausal female patients with rheumatoid arthritis.

1996 • 92 citations

Relation of menstrual cycle phase to symptoms of rheumatoid arthritis

1983 • 92 citations

Safety of Hormone Replacement Therapy (HRT) in Systemic Lupus Erythematosus (SLE)

1994 • 90 citations

Oestrogen induced suppression of collagen arthritis: I. Long term oestradiol treatment of DBA/1 mice reduces severity and incidence of arthritis and decreases the anti type II collagen immune response.

1987 • 90 citations

CASE-CONTROL STUDY OF RHEUMATOID ARTHRITIS AND PRIOR USE OF ORAL CONTRACEPTIVES

1983 • 89 citations

BREAST FEEDING, OTHER REPRODUCTIVE FACTORS AND RHEUMATOID ARTHRITIS. A PROSPECTIVE STUDY

1995 • 87 citations

Postmenopausal estrogen replacement therapy and the risk of developing systemic lupus erythematosus or discoid lupus.

1998 • 87 citations

The beneficial effects of treatment with tamoxifen and anti‐oestradiol antibody on experimental systemic lupus erythematosus are associated with cytokine modulations

1997 • 86 citations

Effects of estrogen on cartilage and experimentally induced osteoarthritis

1979 • 86 citations

Exogenous sex hormones and the risk of rheumatoid arthritis

1990 • 82 citations

Effects of hormone replacement therapy in rheumatoid arthritis: a double blind placebo-controlled study.

1994 • 79 citations

Hormone replacement therapy in systemic lupus erythematosus.

1997 • 78 citations

A genetic association study of the IGF-1 gene and radiological osteoarthritis in a population-based cohort study (the Rotterdam study)

1998 • 76 citations

Safety of Hormonal Replacement Therapy in Postmenopausal Patients with Systemic Lupus Erythematosus

1998 • 75 citations

Relations between steroid hormones and cytokines in rheumatoid arthritis and systemic lupus erythematosus

1998 • 73 citations

Endogenous sex steroid levels in women with generalised osteoarthritis

1991 • 73 citations

Osteoarthritis in women: Its relationship to estrogen and current trends

1992 • 72 citations

Lifestyle factors and hip arthrosis: A case referent study of body mass index, smoking and hormone therapy in 503 Swedish women

1997 • 72 citations

Estrogens and Osteoarthritis

1986 • 71 citations

Ovarian failure and flares of systemic lupus erythematosus

1999 • 71 citations

Hormone replacement therapy, other reproductive variables and symptomatic hip osteoarthritis in elderly white women: a case-control study

1998 • 70 citations

Controversy of Oral Contraceptives and Risk of Rheumatoid Arthirtis: Meta-analysis of Conflicting Studies and Review of Conflicting Meta-analyses with Special Emphasis on Analysis of Heterogeneity

1996 • 70 citations

Sex hormone status in women suffering from rheumatoid arthritis.

1986 • 67 citations

Serum sex hormones and severity of osteoarthritis of the hand.

1993 • 67 citations

Are both genetic and reproductive associations with rheumatoid arthritis linked to prolactin?

1996 • 66 citations

Effect of oestrogen treatment on clinical and laboratory manifestations of rheumatoid arthritis.

1987 • 66 citations

Estrogen Replacement Therapy and the Development of Osteoarthritis

1996 • 64 citations

Allelic markers close to prolactin are associated with HLA‐DRB1 susceptibility alleles among women with rheumatoid arthritis and systemic lupus erythematosus

1997 • 61 citations

Serum androgen-anabolic hormones and the risk of rheumatoid arthritis

1998 • 59 citations

Body composition in systemic lupus erythematosus

1998 • 57 citations

Can Women with Systemic Lupus Erythematosus Safely Use Exogenous Estrogens?

1995 • 57 citations

Sex hormones in postmenopausal HLA-identical rheumatoid arthritis discordant sibling pairs.

1992 • 56 citations

The Pathogenesis of Osteoarthritis

2007 • 55 citations

Adjuvant oestrogen therapy does not improve disease activity in postmenopausal patients with rheumatoid arthritis.

1993 • 55 citations

Perturbations of hypothalamic-pituitary-gonadal (HPG) axis and adrenal androgen (AA) functions in rheumatoid arthritis

1996 • 53 citations

Fatal exacerbation of systemic lupus erythematosus after induction of ovulation.

1997 • 53 citations

Depressed levels of dehydroepiandrosterone sulphate in postmenopausal women with rheumatoid arthritis but no relation with axial bone density.

1993 • 53 citations

Dehydroepiandrosterone sulfate is positively correlated with soluble interleukin 2 receptor and soluble intercellular adhesion molecule in systemic lupus erythematosus.

1996 • 51 citations

Frequency of osteoarthritis in hysterectomized women.

1991 • 50 citations

HYPOTHALAMIC-PITUITARY MEDIATED MODULATION OF IMMUNE FUNCTION: PROLACTIN AS A NEUROIMMUNE PEPTIDE

1991 • 50 citations

Modifying Action of Estrogen on the Evolution of Osteoarthrosis in Mice of Different Ages

1963 • 49 citations

HIGHER INCIDENCE OF CARPAL TUNNEL SYNDROME IN OOPHORECTOMIZED WOMEN

1991 • 46 citations

Association of oestrogen receptor gene polymorphisms with age at onset of rheumatoid arthritis

1999 • 45 citations

RHEUMATIC DISEASE, ABNORMAL SEROLOGY, AND ORAL CONTRACEPTIVES

1972 • 43 citations

Does estrogen replacement therapy protect against rheumatoid arthritis?

1991 • 43 citations

Non-Contraceptive Hormones and the Risk of Rheumatoid Arthritis in Menopausal Women

1994 • 42 citations

Postmenopausal hormones and the incidence of rheumatoid arthritis.

1989 • 42 citations

Osteogenesis imperfecta. a model for genetic causes of osteoporosis and perhaps several other common diseases of connective tissue

1988 • 41 citations

Estrogen replacement therapy modulation of the insulin-like growth factor system in monkey knee joints

1999 • 40 citations

Association of estrogen replacement therapy with the risk of osteoarthritis of the hip in elderly white women. Study of Osteoporotic Fractures Research Group

1996 • 36 citations

Oral Contraceptives and the Risk of Rheumatoid Arthritis: A Meta-Analysis of a Conflicting Literature

1989 • 34 citations

Hormone replacement therapy in postmenopausal women with systemic lupus erythematosus.

1998 • 34 citations

Inhibition of estradiol-induced early osteoarthritic changes by tamoxifen

1992 • 31 citations

Obstetric and gynaecological factors in susceptibility to peripheral joint osteoarthritis.

1996 • 28 citations

Estrogen Replacement Therapy and Incidence of Self-Reported Physician-Diagnosed Arthritis

1999 • 27 citations

92038378 Does estrogen replacement therapy protect against rheumatoid arthritis?

1992 • 26 citations

An Investigation of Gene-Environment Interaction in the Etiology of Rheumatoid Arthritis

1994 • 25 citations

Carpal Tunnel Syndrome in Ovariectomized Women

1977 • 25 citations

Noncontraceptive hormones and rheumatoid arthritis in perimenopausal and postmenopausal women

1986 • 23 citations

Postmenopausal hormones and the incidence of rheumatoid arthritis

1990 • 23 citations

5 Prolactin and related peptides in pregnancy

1990 • 16 citations

Salivary testosterone in postmenopausal women with rheumatoid arthritis.

1998 • 15 citations

Response of carpal tunnel syndrome to hormone replacement therapy.

1991 • 13 citations

The effects of estrogens on cartilage degradation usingin vivo andin vitro models

1991 • 6 citations

[Increase in plasma androgens in menopausal women with rheumatoid polyarthritis].

1990 • 5 citations

Deleted Work

1955 • 0 citations