Age-related events in active T subpopulations. Changes in polyphosphoinositide metabolism during mitogenic activation

Inositol phosphates and cell signalling

1989 • 4,058 citations

Admission criteria for immunogerontological studies in man: The senieur protocol

1984 • 754 citations

The polyphosphoinositide cycle exists in the nuclei of Swiss 3T3 cells under the control of a receptor (for IGF-I) in the plasma membrane, and stimulation of the cycle increases nuclear diacylglycerol and apparently induces translocation of protein kinase

1991 • 454 citations

Synthesis of polyphosphoinositides in nuclei of Friend cells. Evidence for polyphosphoinositide metabolism inside the nucleus which changes with cell differentiation

1987 • 310 citations

Diphosphoinositide and triphosphoinositide in animal tissues. Extraction, estimation and changes post mortem

1965 • 174 citations

Increased number of circulating Leu 11+ (CD 16) large granular lymphocytes and decreased NK activity during human ageing.

1987 • 170 citations

Changes in nuclear inositol phospholipids induced in intact cells by insulin-like growth factor I

1989 • 106 citations

Relationship between Aging and the Immune System

2015 • 78 citations

Aging and the immune response : cellular and humoral aspects

1987 • 73 citations

Subpopulations of human T lymphocytes. X. Alterations in T, B, third population cells, and T cells with receptors for immunoglobulin M (Tmu) or G (Tgamma) in aging humans.

1979 • 72 citations

Temporal changes in intracellular distribution of protein kinase C in Swiss 3T3 cells during mitogenic stimulation with insulin-like growth factor I and bombesin: Translocation to the nucleus follows rapid changes in nuclear polyphosphoinositides

1991 • 70 citations

Mitogen‐stimulated events in nuclei of Swiss 3T3 cells Evidence for a direct link between changes of inositol lipids, protein kinase C requirement and the onset of DNA synthesis

1991 • 60 citations

Concanavalin‐A‐Activated Lymphocytes Suppress Immune Responses in Vitro but Are Helper Cells in Vivo

1985 • 28 citations

The active T rosette: an early marker for T-cell activation.

1982 • 20 citations

Mitogen-induced phosphorylation of cytosolic proteins in rabbit T- and B-lymphocytes

1985 • 14 citations

Mitogen-induced phosphorylation of human B-lymphocyte proteins. Relationship to protein kinase C activation

1989 • 9 citations

Active E rosette formation by human lymphoblasts.

1978 • 7 citations

Mitogenic stimulation of human B lymphocytes via the inositol phospholipid 'dual pathway' of signalling requires persistent activation of both second messenger arms.

1988 • 5 citations