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Spermine depresses NMDA, K/AMPA and GABAA-mediated synaptic transmission in the rat hippocampal slice preparation

Data up to Jan 2025

Published1994
Citations18
References27

Total Citations Per Year

Abstract

References (27)

POLYAMINES

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Cooperative Modulation of [3H]MK‐801 Binding to the N‐Methyl‐d‐Aspartate Receptor‐Ion Channel Complex by l‐Glutamate, Glycine, and Polyamines

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Paired‐pulse depression of monosynaptic GABA‐mediated inhibitory postsynaptic responses in rat hippocampus.

1990 • 709 citations

Modulation of the NMDA receptor by polyamines

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1989 • 224 citations

Multiple effects of spermine on N‐methyl‐D‐aspartic acid receptor responses of rat cultured hippocampal neurones.

1993 • 199 citations

Characterization of polyamines having agonist, antagonist, and inverse agonist effects at the polyamine recognition site of the NMDA receptor

1990 • 170 citations

Interactions of polyamines with neuronal ion channels

1993 • 158 citations

The polyamine spermine has multiple actions on N-methyl-D-aspartate receptor single-channel currents in cultured cortical neurons.

1992 • 118 citations

Spermine and related polyamines produce a voltage-dependent reduction of N-methyl-D-aspartate receptor single-channel conductance.

1992 • 96 citations

Polyamine metabolism in different pathological states of the brain

1992 • 95 citations

Spermine and philanthotoxin potentiate excitatory amino acid responses of Xenopus oocytes injected with rat and chick brain RNA

1990 • 91 citations

Hyperpolarizing and depolarizing GABAA receptor-mediated dendritic inhibition in area CA1 of the rat hippocampus

1991 • 91 citations

Selective Release of Spermine and Spermidine from the Rat Striatum by N‐Methyl‐<scp>d</scp>‐Aspartate Receptor Activation In Vivo

1992 • 86 citations

Polyamine reutilization and turnover in brain

1985 • 74 citations

Changes in Polyamine Levels in Rat Brain After Systemic Kainic Acid Administration: Relationship to Convulsant Activity and Brain Damage

1991 • 71 citations

ω-Conotoxin GVIA blocks synaptic transmission in the CA1 field of the hippocampus

1989 • 56 citations

Actions of arginine polyamine on voltage and ligand‐activated whole cell currents recorded from cultured neurones

1992 • 52 citations

Effects of polyamines on NMDA-induced currents in rat hippocampal neurons: A whole-cell and single-channel study

1993 • 46 citations

Changes in regional polyamine profiles in rat brains after transient cerebral ischemia (single versus repetitive ischemia): Evidence for release of polyamines from injured neurons

1992 • 45 citations

Polyamines allosterically modulate [3H]nitrendipine binding to the voltage-sensitive calcium channel in rat brain

1992 • 42 citations

The polyamine spermine affects ω‐conotoxin binding and function at N‐type voltage‐sensitive calcium channels

1990 • 36 citations

1,5-(Diethylamino)piperidine, a novel spermidine analogue that more specifically activates the N-methyl-D-aspartate receptor-associated polyamine site.

1992 • 18 citations

Modulation of A1 adenosine receptor function in rat brain by the polyamine, spermine

1991 • 17 citations

Quisqualate-sensitive glutamate receptors of the locust Schistocerca gregaria are antagonised by intracellularly applied philanthotoxin and spermine

1991 • 16 citations

Polyamine modulation of excitatory amino acid responses in the rat cortical wedge

1993 • 8 citations

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Spermine depresses NMDA, K/AMPA and GABAA-mediated synaptic transmission in the rat… (1994) – Brain Research | Metascience Observatory Explorer