Acetylator phenotyping of tuberculosis patients using matrix isoniazid or sulphadimidine and its prognostic significance for treatment with several intermittent isoniazid‐containing regimens.

Isoniazid Liver Injury: Clinical Spectrum, Pathology, and Probable Pathogenesis

1976 • 513 citations

Practical clinical biochemistry.

1963 • 345 citations

Increased incidence of isoniazid hepatitis in rapid acetylators: possible relation to hydrazine metabolites

1975 • 301 citations

An improved and simplified method of detecting the acetylator phenotype.

1969 • 238 citations

Pharmacokinetics of isoniazid metabolism in man

1976 • 183 citations

Variations between individuals and populations in the acetylation of isoniazid and its significance for the treatment of pulmonary tuberculosis

1976 • 134 citations

Short-course chemotherapy for pulmonary tuberculosis.

1975 • 132 citations

GENETIC VARIATIONS IN THE ACETYLATION OF ISONIAZID AND OTHER DRUGS

1968 • 95 citations

Studies on the metabolic basis for the genetically determined capacities for isoniazid inactivation in man.

1965 • 81 citations

Sulphadimidine Acetylation Test for Classification of Patients as Slow or Rapid Inactivators of Isoniazid

1970 • 73 citations

Controlled trial of 6- and 9-month regimens of daily and intermittent streptomycin plus isoniazid plus pyrazinamide for pulmonary tuberculosis in Hong Kong

1975 • 72 citations

The determination of isoniazid and its metabolites acetylisoniazid, monoacetylhydrazine, diacetylhydrazine, isonicotinic acid and isonicotinylglycine in serum and urine

1972 • 70 citations

SHORT-COURSE CHEMOTHERAPY IN PULMONARY TUBERCULOSIS

1976 • 61 citations

A controlled comparison of a twice-weekly and three once-weekly regimens in the initial treatment of pulmonary tuberculosis.

1970 • 55 citations

Clinical Lectures ON THE BORDERLAND OF EPILEPSY: VERTIGO: Delivered at the National Hospital for the Paralysed and Epileptic

1906 • 49 citations

General considerations in the choice and management of regimens of chemotherapy for pulmonary tuberculosis.

1972 • 36 citations

The determination of the acetylator phenotype of tuberculosis patients in czechoslovakia using sulhpadimidine

1973 • 32 citations

Genetic Factors in Relation to Drugs

1968 • 31 citations

A controlled comparison of two fully supervised once-weekly regimens in the treatment of newly diagnosed pulmonary tuberculosis

1973 • 30 citations

Rapid determination of isonicotinic acid hydrazide in whole blood with 2,4,6-trinitrobenzenesulphonic acid

1970 • 28 citations

The discrimination of phenotypes for rate of disappearance of isonicotinoyl hydrazide from serum

1969 • 25 citations

Determination of the acetylator phenotype using matrix isoniazid

1975 • 24 citations

Method for the estimation of acetylisoniazid in urine

1968 • 22 citations

Controlled Comparison of Oral Twice-weekly and Oral Daily Isoniazid plus PAS in Newly Diagnosed Pulmonary Tuberculosis

1973 • 21 citations

Further studies on the pharmacology of a slow-release matrix preparation of isoniazid (Smith & Nephew hs 82) of potential use in the intermittent treatment of tuberculosis

1973 • 21 citations

GENETIC VARIATIONS IN THE ACETYLATION OF ISONIAZID AND OTHER DRUGS

1968 • 21 citations

FURTHER OBSERVATIONS ON TRIMODALITY OF FREQUENCY DISTRIBUTION CURVE OF BIOLOGICALLY ACTIVE ISONIAZID BLOOD LEVELS AND "CLINE" INFREQUENCIES OF ALLELES CONTROLLING ISONIAZID INACTIVATION.

1963 • 21 citations

A slow-release preparation of isoniazid: pharmacological aspects.

1976 • 14 citations

A modified method for the estimation of acetylisoniazid in urine.

1974 • 12 citations

A slow-release preparation of isoniazid: therapeutic efficacy and adverse side-effects.

1976 • 11 citations

Isoniazid and psuedocholinesterase polymorphisms.

1972 • 9 citations

Classification of subjects as slow or rapid inactivators of isoniazid oral administration of a slow-release preparation of isoniazid and determination of the ratio of acetylisoniazid to isoniazid in urine.

1975 • 8 citations