Reciprocal stimulation of negatively selected high-responder and low-responder T cells in virus-infected recipients.

The somatic generation of immune recognition

1971 • 974 citations

On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition?

1978 • 870 citations

Immunological surveillance against altered self components by sensitised T lymphocytes in lymphocytes choriomeningitis

1974 • 832 citations

Major histocompatibility complex-linked immune-responsiveness is acquired by lymphocytes of low-responder mice differentiating in thymus of high-responder mice.

1978 • 353 citations

The lymphoreticular system in triggering virus plus self-specific cytotoxic T cells: evidence for T help.

1978 • 268 citations

Ir-genes in H-2 regulate generation of anti-viral cytotoxic T cells. Mapping to K or D and dominance of unresponsiveness.

1978 • 166 citations

Cytotoxic T-cell responses in mice infected with influenza and vaccinia viruses vary in magnitude with H-2 genotype.

1978 • 166 citations

The Allogeneic Effect on Immune Responses: Model for Regulatory Influences of T Lymphocytes on the Immune System

1972 • 98 citations

Helper function of T cells depleted of alloantigen-reactive lymphocytes by filtration through irradiated F1 hybrid recipients. I. Failure to collaborate with allogeneic B cells in a secondary response to sheep erythrocytes measured in vivo.

1976 • 83 citations

Vaccinia-specific cytotoxic T-cell responses in the context of H-2 antigens not encountered in thymus may reflect aberrant recognition of a virus-H-2 complex.

1979 • 80 citations

In irradiation chimeras, K or D regions of the chimeric host, not of the donor lymphocytes, determine immune responsiveness of antiviral cytotoxic T cells

1978 • 62 citations

Immunological studies of T-cell receptors. II. Limited polymorphism of idiotypic determinants on T-cell receptors specific for major histocompatibility complex alloantigens.

1979 • 54 citations

Different rules govern help for cytotoxic T cells and B cells

1978 • 48 citations

Positive and Negative Allogeneic Effects Mediated by MLR-Primed Lymphocytes: Quantitation by Limiting Dilution Analysis

1978 • 40 citations

T-cell populations specifically depleted of alloreactive potential cannot be induced to lyse H-2-different virus-infected target cells.

1978 • 40 citations

Cytotoxic T-cell response to ectromelia virus-infected cells. Different H-2 requirements for triggering precursor T-cell induction or lysis by effector T cells defined by the BALB/c-H-2(db) mutation

1977 • 37 citations

Regulation of the T-cell response to ectromelia virus infection. I. Feedback suppression by effector T cells.

1976 • 31 citations

Genetic control of cytolytic t-lymphocyte responses. II. The role of the host genotype in parental leads to F1 radiation chimeras in the control of the specificity of cytolytic T-lymphocyte responses to trinitrophenyl-modified syngeneic cells.

1978 • 26 citations