Nonpeptide antagonists herald new era in tachykinin research

A Potent Nonpeptide Antagonist of the Substance P (NK ₁ ) Receptor

1991 • 875 citations

Tachykinins

1988 • 542 citations

Mammalian Tachykinin Receptors

1991 • 502 citations

A potent and selective non-peptide antagonist of the neurokinin a (NK2) receptor

1992 • 441 citations

Tachykinin receptor types: Classification and membrane signalling mechanisms

1991 • 342 citations

Investigation into species variants in tachykinin NK₁ receptors by use of the non‐peptide antagonist, CP‐96,345

1991 • 224 citations

Activity and Distribution of Binding Sites in Brain of a Nonpeptide Substance P (NK ₁ ) Receptor Antagonist

1991 • 221 citations

The non‐peptide tachykinin antagonist, CP‐96,345, is a potent inhibitor of neurogenic inflammation

1992 • 185 citations

Species differences in affinities of non-peptide antagonists for substance p receptors

1991 • 163 citations

Novel substance P antagonist, CP-96,345, blocks responses of cat spinal dorsal horn neurons to noxious cutaneous stimulation and to substance P

1991 • 136 citations

The non‐peptide NK₁ receptor antagonist, (±)‐CP‐96,345, produces antinociceptive and anti‐oedema effects in the rat

1992 • 118 citations

Inhibition of neurogenic plasma exudation in guinea‐pig airways by CP‐96,345, a new non‐peptide NK₁ receptor antagonist

1992 • 107 citations

Role of NK1 tachykinin receptors in thermonociception: Effect of (±)-CP 96,345, a non-peptide substance P antagonist, on the hot plate test in mice

1991 • 74 citations

Formoterol and salbutamol inhibit bradykinin‐ and histamine‐induced airway microvascular leakage in guinea‐pig

1992 • 70 citations

Antagonists that demonstrate species differences in neurokinin-1 receptors.

1992 • 66 citations

Synthesis and substance P receptor binding activity of androstano[3,2-b]pyrimido[1,2-a]benzimidazoles

1992 • 65 citations

Cigarette smoke-induced airway oedema is blocked by the NK1 antagonist, CP-96,345

1991 • 60 citations