Molecular Characterization of the Glucose-Sensing Mechanism in the Clonal Insulin-Secreting BRIN-BD11 Cell Line

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Method for the Isolation of Intact Islets of Langerhans from the Rat Pancreas

1967 • 2,783 citations

Reconstitution of I _KATP : An Inward Rectifier Subunit Plus the Sulfonylurea Receptor

1995 • 1,703 citations

Cloning of the β Cell High-Affinity Sulfonylurea Receptor: a Regulator of Insulin Secretion

1995 • 1,310 citations

Cloning and functional expression in bacteria of a novel glucose transporter present in liver, intestine, kidney, and β-pancreatic islet cells

1988 • 786 citations

Glucokinase as Glucose Sensor and Metabolic Signal Generator in Pancreatic β-Cells and Hepatocytes

1990 • 603 citations

Continuous, clonal, insulin- and somatostatin-secreting cell lines established from a transplantable rat islet cell tumor.

1980 • 496 citations

Cloning and Functional Characterization of a Novel ATP-sensitive Potassium Channel Ubiquitously Expressed in Rat Tissues, including Pancreatic Islets, Pituitary, Skeletal Muscle, and Heart

1995 • 405 citations

DNA fluorometric assay in 96-well tissue culture plates using Hoechst 33258 after cell lysis by freezing in distilled water

1990 • 395 citations

Characterization of a Novel Glucose-Responsive Insulin-Secreting Cell Line, BRIN-BD11, Produced by Electrofusion

1996 • 345 citations

A transplantable insulinoma in the rat.

1977 • 308 citations

Intestinal Epithelial Cell Surface Membrane Glycoprotein Synthesis

1973 • 187 citations

Intracellular degradation of insulin stores by rat pancreatic islets in vitro. An alternative pathway for homeostasis of pancreatic insulin content.

1980 • 168 citations

Overexpression of hexokinase I in isolated islets of Langerhans via recombinant adenovirus. Enhancement of glucose metabolism and insulin secretion at basal but not stimulatory glucose levels.

1994 • 151 citations

Nutrient regulation of insulin secretion

1993 • 149 citations

Nutrient regulation of insulin secretion

1992 • 120 citations

Mechanisms of amino acid-induced insulin secretion from the glucose-responsive BRIN-BD11 pancreatic B-cell line

1996 • 114 citations

Frontiers of insulin secretion and pancreatic B-cell research

1994 • 90 citations

Signal recognition by pancreatic B-cells

1988 • 68 citations

Reduction of the cytosolic calcium activity in clonal insulin-releasing cells exposed to glucose

1983 • 45 citations

Human Islet Glucokinase Gene: Isolation and Sequence Analysis of Full-Length cDNA

1992 • 41 citations

Hexose Recognition by Insulin-Secreting BRIN-BD11 Cells

1996 • 29 citations

Regulation of pancreatic B-cell glucokinase and GLUT2 glucose transporter gene expression

1994 • 9 citations

Characteristics of BRIN-BG5 and BRIN-BG7, two novel glucose-responsive insulin-secreting cell lines produced by electrofusion

1996 • 9 citations