Biodistribution and Toxicity Studies of VSVG-Pseudotyped Lentiviral Vector after Intravenous Administration in Mice with the Observation of in Vivo Transduction of Bone Marrow

Real time quantitative PCR.

1996 • 6,155 citations

In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector

1996 • 4,854 citations

A Third-Generation Lentivirus Vector with a Conditional Packaging System

1998 • 3,175 citations

Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector.

1996 • 1,516 citations

Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells.

1993 • 1,395 citations

Development of a Self-Inactivating Lentivirus Vector

1998 • 1,169 citations

Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector

1997 • 732 citations

A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection

1989 • 692 citations

Transduction of Human CD34 ⁺ Cells That Mediate Long-Term Engraftment of NOD/SCID Mice by HIV Vectors

1999 • 648 citations

Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors

1997 • 614 citations

Stable and efficient gene transfer into the retina using an HIV-based lentiviral vector

1997 • 499 citations

Efficient transduction of nondividing human cells by feline immunodeficiency virus lentiviral vectors

1998 • 421 citations

Stable transduction of quiescent CD34⁺CD38⁻human hematopoietic cells by HIV-1-based lentiviral vectors

1999 • 407 citations

Transduction of nondividing cells using pseudotyped defective high-titer HIV type 1 particles

1996 • 384 citations

Epitopes of the CD4 Antigen and HIV Infection

1986 • 379 citations

Developments in Quantitative PCR

1998 • 345 citations

Efficient lentiviral transduction of liver requires cell cycling in vivo

2000 • 327 citations

An inherited limb deformity created by insertional mutagenesis in a transgenic mouse

1985 • 294 citations

Minimal Requirement for a Lentivirus Vector Based on Human Immunodeficiency Virus Type 1

1998 • 263 citations

A Packaging Cell Line for Lentivirus Vectors

1999 • 257 citations

Efficacy and safety analyses of a recombinant human immunodeficiency virus type 1 derived vector system

1999 • 236 citations

Partial reverse transcripts in virions from human immunodeficiency and murine leukemia viruses

1992 • 221 citations

Lentiviral Vectors--the Promise of Gene Therapy Within Reach?

1999 • 168 citations

The glycoprotein G of rhabdoviruses

1995 • 160 citations

Critical Factors Influencing Stable Transduction of Human CD34+ Cells with HIV-1-Derived Lentiviral Vectors

2000 • 156 citations

Latest Developments in Gene Transfer Technology: Achievements, Perspectives, and Controversies over Therapeutic Applications

2000 • 150 citations

Characterization of Membrane Components of the Erythrocyte Involved in Vesicular Stomatitis Virus Attachment and Fusion at Acidic pH

1987 • 140 citations

Transduction of Human PBMC-Derived Dendritic Cells and Macrophages by an HIV-1-Based Lentiviral Vector System

2000 • 127 citations

Lentiviral Vectors for Gene Therapy of Cystic Fibrosis

1997 • 112 citations

Pseudotyped human lentiviral vector-mediated gene transfer to airway epithelia in vivo

2000 • 103 citations

Human Infection with the Virus of Vesicular Stomatitis during an Epizootic

1967 • 89 citations

Gene transfer into stimulated and unstimulated T lymphocytes by HIV-1-derived lentiviral vectors

2000 • 87 citations

Legless, a Novel Mutation Found in PHT1-1 Transgenic Mice

1988 • 86 citations

Use of a temperature-sensitive mutant to define the biological effects of the p210BCR-ABL tyrosine kinase on proliferation of a factor-dependent murine myeloid cell line.

1994 • 74 citations

Quantitative Determination of Lentiviral Vector Particle Numbers by Real-Time PCR

2001 • 71 citations

Efficient Transduction of Human Lymphocytes and CD34+ Cells via Human Immunodeficiency Virus-Based Gene Transfer Vectors

1999 • 58 citations

Real-Time Quantitative Polymerase Chain Reaction to Assess Gene Transfer

1999 • 39 citations

Preclinical Development Strategies for Novel Gene Therapeutic Products

1999 • 35 citations

Germline alteration by gene therapy: assessing and reducing the risks

1998 • 30 citations

Lentiviral‐mediated gene transfer into haematopoietic stem cells

2001 • 29 citations

Preclinical safety evaluation of human gene therapy products

1999 • 27 citations

Lentiviral vectors: progress and potential.

2000 • 26 citations

Lentiviral Vectors Approach the Clinic but Fall Back: National Institutes of Health Recombinant DNA Advisory Committee Review of a First Clinical Protocol for Use of a Lentiviral Vector

2001 • 25 citations

Characterization of New Jersey vesicular stomatitis virus isolates from horses and black flies during the 1982 outbreak in Colorado

1985 • 24 citations

Clinical Gene Therapy in Hematology: Past and Future

2001 • 23 citations

The Role of the Toxicologic Pathologist in the Preclinical Safety Evaluation of Biotechnology-Derived Pharmaceuticals

1999 • 19 citations

Membrane Fusion as a Determinant of the Infectibility of Cells by Vesicular Stomatitis Virus

1994 • 6 citations