Enhanced expression of thrombospondin-1 and hypovascularity in human cholangiocarcinoma

Angiogenesis in cancer, vascular, rheumatoid and other disease

1995 • 7,717 citations

Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis

1996 • 6,878 citations

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

1993 • 3,605 citations

The fms -Like Tyrosine Kinase, a Receptor for Vascular Endothelial Growth Factor

1992 • 2,042 citations

Control of Angiogenesis in Fibroblasts by p53 Regulation of Thrombospondin-1

1994 • 1,460 citations

Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant

1994 • 1,249 citations

Vascular permeability factor (VPF, VEGF) in tumor biology

1993 • 839 citations

The structure of human thrombospondin, an adhesive glycoprotein with multiple calcium-binding sites and homologies with several different proteins.

1986 • 575 citations

Peptides derived from two separate domains of the matrix protein thrombospondin-1 have anti-angiogenic activity

1993 • 574 citations

Detection of p53 Gene Mutations in Human Brain Tumors by Single-strand Conformation Polymorphism Analysis of Polymerase Chain Reaction Products

1991 • 556 citations

Dominant-negative inhibition of Flk-1 suppresses the growth of many tumor types in vivo.

1996 • 423 citations

The role of vascular endothelial growth factor in pathological angiogenesis

1995 • 419 citations

Wild-type p53 and v-Src exert opposing influences on human vascular endothelial growth factor gene expression.

1995 • 409 citations

Transfection of thrombospondin 1 complementary DNA into a human breast carcinoma cell line reduces primary tumor growth, metastatic potential, and angiogenesis.

1994 • 352 citations

Analysis of the p53 gene and its expression in human glioblastoma cells.

1994 • 329 citations

Thrombospondin-1 Expression in Bladder Cancer: Association With p53 Alterations, Tumor Angiogenesis, and Tumor Progression

1997 • 328 citations

Clinical significance of vascular endothelial growth factor and basic fibroblast growth factor gene expression in liver tumor

1996 • 306 citations

Expression of vascular endothelial growth factor and its possible relation with neovascularization in human brain tumors

1995 • 271 citations

Inhibition of tumor growth and metastasis by an immunoneutralizing monoclonal antibody to human vascular endothelial growth factor/vascular permeability factor121.

1995 • 257 citations

Expression of vascular permeability factor/vascular endothelial growth factor in human hepatocellular carcinoma.

1996 • 221 citations

AIDS-associated kaposi's sarcoma cells in culture express vascular endothelial growth factor

1992 • 164 citations

Thrombospondin 1 expression in transformed endothelial cells restores a normal phenotype and suppresses their tumorigenesis.

1995 • 162 citations

Inhibition of angiogenesis in human glioblastomas by chromosome 10 induction of thrombospondin-1.

1996 • 145 citations

The role of thrombospondin‐1 in tumor progression and angiogenesis

1996 • 124 citations

Thrombospondin-1 and -2 messenger RNA expression in normal, benign, and neoplastic human breast tissues: correlation with prognostic factors, tumor angiogenesis, and fibroblastic desmoplasia.

1997 • 113 citations

Enhanced coexpression of thioredoxin and high mobility group protein 1 genes in human hepatocellular carcinoma and the possible association with decreased sensitivity to cisplatin.

1996 • 103 citations

Localization of thrombospondin in hepatocellular carcinoma

1997 • 21 citations