The peptide binding specificity of HLA class I molecules is largely allele-specific and non-overlapping

The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens

1987 • 2,403 citations

Spontaneous inflammatory disease in transgenic rats expressing HLA-B27 and human β2m: An animal model of HLA-B27-associated human disorders

1990 • 1,001 citations

Association of class I major histocompatibility heavy and light chains induced by viral peptides

1989 • 995 citations

Conserved features of eukaryotic hsp70 genes revealed by comparison with the nucleotide sequence of human hsp70.

1985 • 860 citations

Isolation of an endogenously processed immunodominant viral peptide from the class I H–2Kb molecule

1990 • 689 citations

Specificity pockets for the side chains of peptide antigens in HLA-Aw68

1989 • 664 citations

Assembly of MHC class I molecules analyzed in vitro

1990 • 491 citations

HIV-1 gag-specific cytotoxic T lymphocytes defined with recombinant vaccinia virus and synthetic peptides

1988 • 447 citations

Cellular peptide composition governed by major histocompatibility complex class I molecules

1990 • 438 citations

NK susceptibility varies inversely with target cell class I HLA antigen expression.

1987 • 433 citations

cDNA sequences of two inducible T-cell genes.

1989 • 392 citations

Nature of polymorphism in HLA-A, -B, and -C molecules.

1988 • 379 citations

Evolution of the major histocompatibility complex.

1986 • 326 citations

Prediction of major histocompatibility complex binding regions of protein antigens by sequence pattern analysis.

1989 • 310 citations

Residues of the variable region of the T-cell-receptor β-chain that interact with S. aureus toxin superantigens

1990 • 301 citations

Role of self-peptides in positively selecting the T-cell repertoire

1990 • 300 citations

Evolution of Class-I MHC Genes and Proteins: From Natural Selection to Thymic Selection

1990 • 286 citations

cDNA cloning and complete primary structure of the alpha subunit of a leukocyte adhesion glycoprotein, p150,95.

1987 • 277 citations

The primary structure of the alpha 4 subunit of VLA-4: homology to other integrins and a possible cell-cell adhesion function.

1989 • 264 citations

Peptide selection by MHC class I molecules

1991 • 253 citations

Recognition of HLA-B27 and related antigen by a monoclonal antibody

1982 • 240 citations

cDNA and amino acid sequences of the cell adhesion protein receptor recognizing vitronectin reveal a transmembrane domain and homologies with other adhesion protein receptors.

1986 • 231 citations

Peptide-induced conformational change of the class I heavy chain

1991 • 221 citations

T cell recognition as the target for immune intervention in autoimmune disease

1989 • 218 citations

In vivo competition between self peptides and foreign antigens in T-cell activation

1988 • 216 citations

Evolution of the major histocompatibility complex

1986 • 142 citations

Mapping the fine specificity of a cytolytic T cell response to HIV-1 nef protein.

1990 • 133 citations

The specific binding of peptide ligand to Ld class I major histocompatibility complex molecules determines their antigenic structure.

1991 • 122 citations

Monoclonal Antibody to HLA-A3

1982 • 115 citations

The self determinants recognized by human virus-immune T cells can be distinguished from the serologically defined HLA antigens.

1980 • 112 citations

Structural homologies between two HLA B27-restricted peptides suggest residues important for interaction with HLA B27

1990 • 105 citations

The α1 domain of the HLA-DR molecule is essential for high-affinity binding of the toxic shock syndrome toxin-1

1990 • 100 citations

Physical association between MHC class I molecules and immunogenic peptides

1989 • 91 citations

Generation of specific cytotoxic T cells with a fragment of the Epstein-Barr virus-encoded p63/latent membrane protein.

1987 • 82 citations

HLA-DR2 subtypes form an additional supertypic family of DR beta alleles.

1987 • 77 citations

HLA-B27 in inbred and non-inbred transgenic mice. Cell surface expression and recognition as an alloantigen in the absence of human beta 2-microglobulin.

1988 • 70 citations

Evidence of widespread binding of HLA class I molecules to peptides.

1990 • 55 citations

Comparison between two peptide epitopes presented to cytotoxic T lymphocytes by HLA-A2. Evidence for discrete locations within HLA-A2.

1989 • 54 citations

Analysis of physical interactions between peptides and HLA molecules and application to the detection of human immunodeficiency virus 1 antigenic peptides.

1990 • 53 citations

HLA-B37 and HLA-A2.1 molecules bind largely nonoverlapping sets of peptides.

1990 • 47 citations

Primary structure of human plasma fibronectin. Characterization of a 38 kDa domain containing the C-terminal heparin-binding site (Hep III site) and a region of molecular heterogeneity

1987 • 47 citations

Serologic Discrimination of Human T Cell Lymphotropic Virus Infection by Using a Synthetic Peptide-Based Enzyme Immunoassay

1991 • 45 citations

Specificity of peptide binding by the HLA-A2.1 molecule.

1989 • 45 citations

Apparent lack of MHC restriction in binding of class I HLA molecules to solid-phase peptides.

1990 • 43 citations

A single amino acid substitution in HLA-A2 can alter the selection of the cytotoxic T lymphocyte repertoire that responds to influenza virus matrix peptide 55-73.

1989 • 28 citations

The kinetics of peptide binding to HLA-A2 and the conformation of the peptide-A2 complex can be determined by amino acid side chains on the floor of the peptide binding groove

1990 • 23 citations