Stable Integration of Human Immunodeficiency Virus-Based Retroviral Vectors into the Chromosomes of Nondividing Cells

Efficient selection for high-expression transfectants with a novel eukaryotic vector

1991 • 5,120 citations

In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector

1996 • 4,854 citations

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

1996 • 4,184 citations

The Basic Science of Gene Therapy

1993 • 1,767 citations

Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector.

1996 • 1,516 citations

Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells.

1993 • 1,395 citations

Oncogenes, antioncogenes, and the molecular bases of multistep carcinogenesis.

1989 • 961 citations

The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells.

1994 • 845 citations

A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells

1993 • 810 citations

Passage through mitosis is required for oncoretroviruses but not for the human immunodeficiency virus

1994 • 798 citations

Helper-free stocks of recombinant adeno-associated viruses: normal integration does not require viral gene expression

1989 • 741 citations

Nucleic acid structure and expression of the human AIDS/lymphadenopathy retrovirus

1985 • 706 citations

Infection of monocyte/macrophages by human T lymphotropic virus type III.

1986 • 682 citations

Pure, postmitotic, polarized human neurons derived from NTera 2 cells provide a system for expressing exogenous proteins in terminally differentiated neurons

1992 • 612 citations

Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: tolerization of factor IX and vector antigens allows for long-term expression.

1995 • 599 citations

Transduction with recombinant adeno-associated virus for gene therapy is limited by leading-strand synthesis

1996 • 542 citations

Cloning of a human seven-transmembrane domain receptor, LESTR, that is highly expressed in leukocytes.

1994 • 460 citations

Improved Methods of Retroviral Vector Transduction and Production for Gene Therapy

1994 • 382 citations

HIV nuclear import is governed by the phosphotyrosine-mediated binding of matrix to the core domain of integrase

1995 • 360 citations

Productive human immunodeficiency virus type 1 (HIV-1) infection of nonproliferating human monocytes.

1991 • 358 citations

HIV-1 infection of nondividing cells: C-terminal tyrosine phosphorylation of the viral matrix protein is a key regulator

1995 • 309 citations

Clonal expansion of human T-cell leukemia virus type I-infected cells in asymptomatic and symptomatic carriers without malignancy

1995 • 308 citations

Adeno-associated virus vectors preferentially transduce cells in S phase.

1994 • 272 citations

Recombinant adeno-associated virus-mediated gene transfer into hematopoietic progenitor cells [published erratum appears in Blood 1995 Feb 1;85(3):862]

1994 • 134 citations

Infection efficiency of T lymphocytes with amphotropic retroviral vectors is cell cycle dependent

1989 • 129 citations

Packaging of human immunodeficiency virus type 1 RNA requires cis-acting sequences outside the 5' leader region

1993 • 111 citations

Recombinant adeno-associated virus-mediated gene transfer into hematopoietic progenitor cells [published erratum appears in Blood 1995 Feb 1;85(3):862]

1994 • 110 citations

Requirement for Cell Division for Initiation of Transcription of Rous Sarcoma Virus RNA

1974 • 107 citations

Targeted and highly efficient gene transfer into CD4+ cells by a recombinant human immunodeficiency virus retroviral vector.

1991 • 105 citations

Cell Cycle-Dependent Activation of Rous Sarcoma Virus-Infected Stationary Chicken Cells: Avian Leukosis Virus Group-Specific Antigens and Ribonucleic Acid

1972 • 77 citations

Inducible human immunodeficiency virus type 1 packaging cell lines

1996 • 76 citations

A human immunodeficiency virus type 1 (HIV-1)-based retroviral vector system utilizing stable HIV-1 packaging cell lines

1994 • 55 citations

Stochastic events in the amplification of HTLV-I integration sites by linker-mediated PCR

1995 • 45 citations

Recombinant adeno-associated virus-mediated high-efficiency, transient expression of the murine cationic amino acid transporter (ecotropic retroviral receptor) permits stable transduction of human HeLa cells by ecotropic retroviral vectors

1996 • 42 citations

Two-Step Gene Transfer Using an Adenoviral Vector Carrying the CD4 Gene and Human Immunodeficiency Viral Vectors

1996 • 22 citations