Preeclampsia selectively impairs endothelium-dependent relaxation and leads to oscillatory activity in small omental arteries.

Placental Cytokines and the Pathogenesis of Preeclampsia

1997 • 476 citations

Elevated glucose impairs endothelium-dependent relaxation by activating protein kinase C.

1991 • 429 citations

Clinical and Biochemical Evidence of Endothelial Cell Dysfunction in the Pregnancy Syndrome Preeclampsia

1991 • 402 citations

Identification of increased nitric oxide biosynthesis during pregnancy in rats

1993 • 394 citations

Hypertension in Pregnancy

1981 • 381 citations

Serial Assessment of the Cardiovascular System in Normal Pregnancy

1997 • 342 citations

Abnormal endothelial cell function of resistance arteries from women with preeclampsia

1993 • 279 citations

Flow-Mediated Vasodilatation Is Enhanced in Normal Pregnancy but Reduced in Preeclampsia

1997 • 237 citations

1,2-Diacylglycerol and phorbol ester inhibit agonist-induced formation of inositol phosphates in human platelets: possible implications for negative feedback regulation of inositol phospholipid hydrolysis.

1985 • 222 citations

Impaired contraction and relaxation in aorta from streptozotocin-diabetic rats: Role of polyol pathway

1992 • 216 citations

Nitric oxide-mediated vasodilation in human pregnancy

1997 • 205 citations

Loss of endothelial pertussis toxin-sensitive G protein function in atherosclerotic porcine coronary arteries.

1991 • 195 citations

Comparison of acetylcholine-dependent relaxation in large and small arteries of rat mesenteric vascular bed

1994 • 192 citations

Human placental syncytiotrophoblast microvillous membranes impair maternal vascular endothelial function

1997 • 170 citations

Bradykinin-mediated relaxation of isolated maternal resistance arteries in normal pregnancy and preeclampsia

1996 • 164 citations

Selective loss of microvascular endothelial function in human hypercholesterolemia.

1994 • 159 citations

Acute blockade of nitric oxide synthase inhibits renal vasodilation and hyperfiltration during pregnancy in chronically instrumented conscious rats.

1995 • 154 citations

The G proteins of the G alpha i and G alpha q family couple the bradykinin receptor to the release of endothelium-derived relaxing factor.

1993 • 126 citations

Potassium channel-mediated relaxation to acetylcholine in rabbit arteries.

1993 • 114 citations

Abnormal vascular function and morphology in preeclampsia: a study of isolated resistance vessels

1985 • 103 citations

Endothelium-Dependent Relaxation of Small Arteries from Essential Hypertensive Patients: Mechanisms and Comparison with Normotensive Subjects and with Responses of Vessels from Spontaneously Hypertensive Rats

1995 • 93 citations

Adverse Interactions Between Pregnancy and a New Model of Systemic Hypertension Produced by Chronic Blockade of Endothelial Derived Relaxing Factor (EDRF) in the Rat

1992 • 93 citations

Vasomotion and underlying mechanisms in small arteries. An in vitro study of rat blood vessels.

1993 • 83 citations

Endothelial Adhesion Molecules and Leukocyte Integrins in Preeclamptic Patients

1997 • 80 citations

Characteristics of vascular smooth muscle in the maternal resistance circulation during pregnancy in the rat

1993 • 75 citations

Pathophysiology of Preeclampsia

1981 • 73 citations

Selective Impairment of Acetylcholine-Mediated Endothelium-Dependent Relaxation in Isolated Resistance Arteries of the Streptozotocin-Induced Diabetic Rat

1995 • 70 citations

Rhythmic smooth muscle activity in hamster aortas is mediated by continuous release of NO from the endothelium

1991 • 63 citations

Effect of Pregnancy on Mechanisms of Relaxation in Human Omental Microvessels

1996 • 54 citations

Isolated mesenteric arteries from pregnant rats show enhanced flow‐mediated relaxation but normal myogenic tone.

1996 • 51 citations

Contraction and endothelium-dependent relaxation in mesenteric microvessels from pregnant rats

1995 • 32 citations

Effects of selected vasoconstrictor agonists on isolated omental artery from premenopausal nonpregnant women and from normal and preeclamptic pregnant women

1996 • 28 citations

In vitro vascular effects of cicletanine in pregnancy‐induced hypertension

1991 • 27 citations

Potassium conductance and oscillatory contractions in tail arteries from genetically hypertensive rats

1989 • 24 citations

Functional and Morphological Properties of Human Omental Resistance Vessels

1981 • 21 citations

Lack of reactivity of uterine arteries from patients with obstetric hemorrhage

1992 • 20 citations

Possible Role of Vascular Oscillatory Activity in the Development of High Blood Pressure in Spontaneously Hypertensive Rats

1988 • 20 citations

Effect of Pregnancy on Vascular Cgmp Production and Vasorelaxation in the Rat

1994 • 9 citations

Effects of pregnancy on femoral microvascular responses in the rat

1996 • 6 citations

Reduced vasomotion may contribute to the decrease in vascular resistance during pregnancy.

1996 • 3 citations