Short-term exposure of rat pancreatic islets to human interleukin-1β increases cellular uptake of calcium

Untersuchungen uber die Harnstoffbildung im Tierkörper

1932 • 3,104 citations

The Fluorometric Measurement of Deoxyribonucleic Acid in Animal Tissues with Special Reference to the Central Nervous System

1958 • 1,786 citations

Intracellular ATP directly blocks K+ channels in pancreatic B-cells

1984 • 1,199 citations

Glucose induces closure of single potassium channels in isolated rat pancreatic β-cells

1984 • 1,099 citations

An improved fluorometric assay for DNA

1971 • 997 citations

Role of Ca2+ in toxic cell killing

1989 • 856 citations

Determination of total serum insulin (IRI) in insulin-treated diabetic patients

1972 • 707 citations

Cytotoxicity of Human p I 7 Interleukin-1 for Pancreatic Islets of Langerhans

1986 • 525 citations

Isolated mouse pancreatic islets in culture: Effects of serum and different culture media on the insulin production of the islets

1978 • 287 citations

Inhibitory Effects of Interleukin 1 on Insulin Secretion, Insulin Biosynthesis, and Oxidative Metabolism of Isolated Rat Pancreatic Islets*

1987 • 278 citations

Immune Hormones (Cytokines); Pathogenic Role in Autoimmune Rheumatic and Endocrine Diseases

1989 • 111 citations

Studies on the Mechanisms Causing Inhibition of Insulin Secretion in Rat Pancreatic Islets Exposed to Human Interleukin-1β Indicate a Perturbation in the Mitochondrial Function*

1989 • 101 citations

The HLA‐IDDM association: Implications for etiology and pathogenesis of IDDM

1987 • 96 citations

Interleukin 1 dose-dependently affects the biosynthesis of (pro)insulin in isolated rat islets of Langerhans

1987 • 92 citations

Simple Method for in Vitro Metabolic Studies Using Small Volumes of Tissue and Medium

1963 • 89 citations

Interleukin 1 Inhibits Insulin Secretion From Isolated Perifused Rat Islets

1986 • 79 citations

Interleukin-1 induced impairment in pancreatic islet oxidative metabolism of glucose is potentiated by tumor necrosis factor

1988 • 78 citations

Lysosomes and pancreatic islet function

1988 • 69 citations

Insulin‐secreting β‐cells possess specific receptors for interleukin‐1β

1990 • 62 citations

Preferential Reduction of Insulin Production in Mouse Pancreatic Islets Maintained in Culture after Streptozotocin Exposure*

1988 • 57 citations

Inhibitor of Interleukin 1 in Normal Human Urine

1988 • 51 citations

Differential Sensitivity to β-Cell Secretagogues in Cultured Rat Pancreatic Islets Exposed to Human Interleukin-1β*

1989 • 49 citations

Effects in vitro of alloxan on the glucose metabolism of mouse pancreatic B-cells

1979 • 38 citations

Pathogenesis of non-insulin dependent diabetes mellitus

1988 • 36 citations

Decreased cell replication and polyamine content in insulin-producing cells after exposure to human interleukin 1β

1989 • 35 citations

Interleukin‐1 inhibits glucose‐induced Ca²⁺ uptake by islets of Langerhans

1989 • 22 citations

Human interleukin-1? induced stimulation of insulin release from rat pancreatic islets is accompanied by an increase in mitochondrial oxidative events

1989 • 20 citations

Effects of natural and recombinant interleukin-1 alpha and -beta on cytosolic free calcium in human and murine fibroblasts.

1988 • 18 citations

Human interleukin 1β stimulates islet insulin release by a mechanism not dependent on changes in phospholipase C and protein kinase C activities or Ca2+ handling

1989 • 14 citations

Modulation of calciumflux influences interleukin 1 β effects on insulin release from isolated islets of Langerhans

1989 • 13 citations