Parametric determinants in pre-stimulus modification of acoustic startle: interaction with ketamine

Statistical principles in experimental design.

1962 • 27,228 citations

Statistical Principles in Experimental Design

1964 • 8,376 citations

The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.

1986 • 1,814 citations

Neuropsychopharmacology

1990 • 1,545 citations

Disorders of attention and perception in early schizophrenia

1961 • 1,198 citations

Prestimulus Effects on Human Startle Reflex in Normals and Schizophrenics

1978 • 1,173 citations

The More or Less Startling Effects of Weak Prestimulation

1975 • 1,113 citations

Reflex modification in the domain of startle: I. Some empirical findings and their implications for how the nervous system processes sensory input.

1980 • 783 citations

Dopaminergic stimulation disrupts sensorimotor gating in the rat

1988 • 609 citations

Effects of phencyclidine and phencyclidine biologs on sensorimotor gating in the rat*1

1989 • 375 citations

Anatomic correlation of NMDA and 3H-TCP-labeled receptors in rat brain

1988 • 284 citations

Modification of the startle reflex in the rat by changes in the auditory and visual environments.

1971 • 261 citations

Neurophysiological studies of sensory gating in rats: Effects of amphetamine, phencyclidine, and haloperidol

1986 • 243 citations

GABAergic projection from nucleus accumbers to ventral pallidum mediates dopamine-induced sensorimotor gating deficits of acoustic startle in rats

1990 • 203 citations

Quantitative autoradiography of [³H]‐MK‐801 binding sites in mammalian brain

1988 • 173 citations

Discordant effects of weak prestimulation on magnitude and latency of the reflex blink

1977 • 141 citations

Apomorphine disrupts the inhibition of acoustic startle induced by weak prepulses in rats

1990 • 141 citations

A D2 dopamine receptor agonist disrupts sensorimotor gating in rats. Implications for dopaminergic abnormalities in schizophrenia.

1990 • 138 citations

Modification of the Acoustic Startle Reflex by a Tactile Prepulse: The Effects of Stimulus Onset Asynchrony and Prepulse Intensity

1987 • 94 citations

Prepulse inhibition of the acoustic startle response is disrupted by N-ethyl-3,4-methylenedioxyamphetamine (MDEA) in the rat

1989 • 66 citations

Effects of experience on stimulus-produced reflex inhibition in the rat.

1973 • 47 citations

Prepulse Rise Time and Startle Reflex Modification: Different Effects for Discrete and Continuous Prepulses

1989 • 34 citations

Temporal integration of acoustic stimulation obtained in reflex inhibition in rats and humans.

1979 • 33 citations

Evidence for an involvement of associative conditioning in reflex modification of the acoustic startle response with gaps in background noise

1990 • 25 citations

Failure of haloperidol to block the disruption of sensory gating induced by phencyclidine and MK801

1989 • 10 citations

Reflex Modification of the Human Auditory Startle Blink by Antecedent Interruption of a Visual Stimulus

1987 • 9 citations