4 Mucosal allergy: role of mast cells and eosinophil granulocytes in the gut

Fatal and Near-Fatal Anaphylactic Reactions to Food in Children and Adolescents

1992 • 1,603 citations

New Concepts about the Mast Cell

1993 • 1,009 citations

Induction of human IgE synthesis in B cells by mast cells and basophils

1993 • 662 citations

The Immunobiology of Eosinophils

1991 • 660 citations

A population study of food intolerance

1994 • 650 citations

RANTES and macrophage inflammatory protein 1 alpha induce the migration and activation of normal human eosinophil granulocytes.

1992 • 620 citations

Adverse reactions to food*

1995 • 580 citations

Immunobiology and immunopathology of human gut mucosa: Humoral immunity and intraepithelial lymphocytes

1989 • 552 citations

Detection of MCT and MCTC types of human mast cells by immunohistochemistry using new monoclonal anti-tryptase and anti-chymase antibodies.

1989 • 411 citations

IgA-induced eosinophil degranulation.

1989 • 397 citations

Human peripheral blood basophils primed by interleukin 3 (IL-3) produce IL-4 in response to immunoglobulin E receptor stimulation.

1993 • 391 citations

Activated mast cells produce interleukin 13.

1995 • 320 citations

Gastrointestinal food hypersensitivity: Basic mechanisms of pathophysiology

1992 • 317 citations

Spontaneous Release of Histamine from Basophils and Histamine-Releasing Factor in Patients with Atopic Dermatitis and Food Hypersensitivity

1989 • 284 citations

c-kit ligand: a unique potentiator of mediator release by human lung mast cells.

1992 • 275 citations

Nerve growth factor induces development of connective tissue-type mast cells in vitro from murine bone marrow cells.

1991 • 274 citations

Quantitative assessment of intestinal eosinophils and mast cells in inflammatory bowel disease

1996 • 261 citations

Regulation and deregulation of human IgE synthesis

1990 • 254 citations

RANTES and related chemokines activate human basophil granulocytes through different G protein‐coupled receptors

1993 • 216 citations

Interleukin 5 modifies histamine release and leukotriene generation by human basophils in response to diverse agonists.

1990 • 213 citations

Histamine suppresses gene expression and synthesis of tumor necrosis factor alpha via histamine H2 receptors.

1991 • 165 citations

Anaphylactic shock during elimination diets for severe atopic eczema.

1984 • 165 citations

Interleukin 3 and granulocyte/macrophage-colony-stimulating factor render human basophils responsive to low concentrations of complement component C3a.

1990 • 160 citations

Latent pulmonary involvement in Crohn's disease: biological, functional, bronchoalveolar lavage and scintigraphic studies.

1986 • 154 citations

Gastrointestinal Dysfunction in Systemic Mastocytosis

1988 • 144 citations

IL-3 and IL-5 prime normal human eosinophils to produce leukotriene C4 in response to soluble agonists.

1991 • 136 citations

Deposition of eosinophil granule major basic protein in eosinophilic gastroenteritis and celiac disease

1992 • 132 citations

Food allergy and intolerance

1992 • 128 citations

Late asthmatic responses: Inquiry into mechanisms and significance

1985 • 122 citations

The jejunal secretion of histamine is increased in active Crohn's disease

1990 • 122 citations

Neutrophil and eosinophil involvement of the small bowel in patients with celiac disease and Crohn's disease: Studies on the secretion rate and immunohistochemical localization of granulocyte granule constituents

1989 • 119 citations

Enhancement of human intestinal mast cell mediator release in active ulcerative colitis

1990 • 117 citations

Mast Cells: The Neuroimmune Connection

2015 • 116 citations

Immunologically mediated food allergy: the importance of food challenge procedures.

1988 • 113 citations

Activated eosinophils and interleukin 5 expression in early recurrence of Crohn's disease.

1995 • 113 citations

Mast cells, T cells and abnormal fibrosis

1985 • 107 citations

Failure to detect IL-3-binding sites on human mast cells.

1990 • 105 citations

Mast Cell Heterogeneity in Man

1985 • 103 citations

IgE-Binding Factors and Regulation of the IgE Antibody Response

1988 • 100 citations

Differential effects of the complement peptides, C5a and C5a des Arg on human basophil and lung mast cell histamine release.

1988 • 100 citations

Serum antibodies to cow's milk proteins in ulcerative colitis and Crohn's disease

1987 • 98 citations

Heterogeneity of human eosinophils

1989 • 98 citations

Immunoreactivity for interleukin 3 and 5 and granulocyte/macrophage colony-stimulating factor of intestinal mucosa in bronchial asthma.

1995 • 97 citations

Colonic mucosal mast cell distribution at line of demarcation of active ulcerative colitis

1992 • 97 citations

Food Allergy and Intolerance

1987 • 93 citations

Immunopharmacology of mast cells and basophils

1993 • 86 citations

Eosinophilic colitis associated with larvae of the pinworm Enterobius vermicularis

1995 • 84 citations

Specific food intolerance: its place as a cause of gastrointestinal symptoms.

1985 • 82 citations

Measurement of intestinal permeability to mannitol and lactulose as a means of diagnosing food allergy and evaluating therapeutic effectiveness of disodium cromoglycate.

1987 • 81 citations

Immunopharmacology of eosinophils

1994 • 72 citations

Adverse reactions to foods

1984 • 71 citations

Intragastral provocation under endoscopic control (IPEC) in food allergy: mast cell and histamine changes in gastric mucosa

1985 • 70 citations

Experimental reproduction of gastric allergy in human beings with controlled observations on the mucosa

1942 • 63 citations

Increased fecal eosinophil cationic protein in inflammatory bowel disease.

1993 • 54 citations

Histamine and histidine decarboxylase are correlated with mucosal repair in rat small intestine after ischemia-reperfusion.

1992 • 49 citations

Immunopharmacology of eosinophils

1993 • 47 citations

IgE in stools as indicator of food sensitization

1995 • 45 citations

Pericrypt eosinophilic enterocolitis and chronic diarrhea

1992 • 45 citations

Anti-immunoglobulin E-stimulated ion transport in human large and small intestine

1993 • 41 citations

Comparison of intestinal mast cell and basophil histamine release in children with food allergic reactions

1989 • 41 citations

Effect of c-kit ligand, stem cell factor, on mediator release by human intestinal mast cells isolated from patients with inflammatory bowel disease and controls.

1996 • 39 citations

Non-IgE antibody mediated mechanisms in food allergy.

1987 • 35 citations

Human Basophils and Mast Cells

1995 • 32 citations

Food allergy: Fact, fiction, and fatality

1993 • 29 citations

Mast cells in areas of experimental bone resorption and remodelling.

1969 • 29 citations

Immune regulation of human colonic electrolyte transport in vitro.

1995 • 27 citations

Intestinal Immunology and Food Allergy

1996 • 20 citations

Abnormal leukotriene C4 released by unaffected jejunal mucosa in patients with inactive Crohn's disease.

1994 • 20 citations

A Comparison Between in Vitro Jejunal Mast Cell Degranulation and Intragastric Challenge in Patients with Suspected Food Intolerance

1985 • 18 citations

Gastric mucosal mast cells in atopic subjects

1995 • 17 citations

Intestinal immunology and food allergy

1995 • 16 citations

Neutrophil and eosinophil involvement of the small bowel affected by chronic alcoholism.

1988 • 11 citations

Antigen-induced histamine-release from duodenal biopsy in gastrointestinal food allergy.

1989 • 11 citations

Effect of the c-<i>kit</i> Ligand on Mediator Release by Human Lung Mast Cells

1992 • 6 citations

Food hypersensitivities: historical perspectives, diagnosis and clinical presentations.

1987 • 6 citations

Mast cells in human polyneuropathies: their density and regional distribution.

1990 • 6 citations

Cell-mediated immunity and mucosal immunity

1994 • 5 citations