Genomic approaches in the management and treatment of breast cancer

Molecular portraits of human breast tumours

2000 • 15,445 citations

Evaluation of Factors Related to Late Recurrence - Later than 10 Years after the Initial Treatment - in Primary Breast Cancer

2013 • 12,861 citations

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

2001 • 10,602 citations

Gene expression profiling predicts clinical outcome of breast cancer

2002 • 9,314 citations

A Gene-Expression Signature as a Predictor of Survival in Breast Cancer

2002 • 6,428 citations

Ki67 expression in breast cancer

2016 • 4,269 citations

Tamoxifen for early breast cancer: an overview of the randomised trials

1998 • 4,082 citations

Relation of tumor size, lymph node status, and survival in 24,740 breast cancer cases

1989 • 2,245 citations

Polychemotherapy for early breast cancer: an overview of the randomised trials. Early Breast Cancer Trialists' Collaborative Group.

1998 • 2,199 citations

Effect of preoperative chemotherapy on the outcome of women with operable breast cancer.

1998 • 2,115 citations

Polychemotherapy for early breast cancer: an overview of the randomised trials

1998 • 2,023 citations

Distinctive gene expression patterns in human mammary epithelial cells and breast cancers

1999 • 1,410 citations

Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors

2002 • 1,114 citations

Pitfalls in the Use of DNA Microarray Data for Diagnostic and Prognostic Classification

2002 • 1,013 citations

Assembly of microarrays for genome-wide measurement of DNA copy number

2001 • 948 citations

Gene expression profiling for the prediction of therapeutic response to docetaxel in patients with breast cancer

2003 • 889 citations

Pathologic findings from the national surgical adjuvant breast project (protocol 6) I. Intraductal carcinoma (DCIS)

1986 • 829 citations

Tamoxifen for early breast cancer: an overview of the randomised trials. Early Breast Cancer Trialists' Collaborative Group.

1998 • 602 citations

Prediction of Relapse or Survival in Patients with Node-Negative Breast Cancer by DNA Flow Cytometry

1989 • 571 citations

Gene Expression Profiles Predict Complete Pathologic Response to Neoadjuvant Paclitaxel and Fluorouracil, Doxorubicin, and Cyclophosphamide Chemotherapy in Breast Cancer

2004 • 545 citations

In vivo gene expression profile analysis of human breast cancer progression.

1999 • 396 citations

Analysis of Loss of Heterozygosity in 399 Premalignant Breast Lesions at 15 Genetic Loci

1998 • 338 citations

Biologic Markers as Predictors of Clinical Outcome From Systemic Therapy for Primary Operable Breast Cancer

1999 • 225 citations

Methods for assessing reproducibility of clustering patterns observed in analyses of microarray data

2002 • 217 citations

Pathologic findings from the national surgical adjuvant breast project (protocol no. 4).V. significance of axillary nodal micro- and macrometastases

1978 • 186 citations

Survival in Hereditary Breast Cancer Associated With Germline Mutations of BRCA2

1999 • 183 citations

Histologic grading of breast cancer.

1980 • 177 citations

Total RNA yield and microarray gene expression profiles from fine‐needle aspiration biopsy and core‐needle biopsy samples of breast carcinoma

2003 • 176 citations

Molecular genetic studies of early breast cancer evolution

1994 • 120 citations

Development and validation of a method for using breast core needle biopsies for gene expression microarray analyses.

2002 • 111 citations

Global Gene Expression Changes During Neoadjuvant Chemotherapy for Human Breast Cancer

2002 • 97 citations

Analysis of gene expression in ductal carcinoma in situ of the breast.

2002 • 91 citations

A faithful method for PCR-mediated global mRNA amplification and its integration into microarray analysis on laser-captured cells

2003 • 89 citations

Interpreting and Integrating Risk Factors for Patients With Primary Breast Cancer

2001 • 31 citations

Herpes simplex encephalitis

2003 • 21 citations

Cancer target discovery using SAGE

2003 • 9 citations