Gdf-8 Propeptide Binds to GDF-8 and Antagonizes Biological Activity by Inhibiting GDF-8 Receptor Binding

TGF-β SIGNAL TRANSDUCTION

1998 • 7,582 citations

An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database

1994 • 6,412 citations

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.

1992 • 4,885 citations

Regulation of skeletal muscle mass in mice by a new TGF-p superfamily member

1997 • 3,802 citations

The Transforming Growth Factor-beta Family

1990 • 3,028 citations

Double muscling in cattle due to mutations in the myostatin gene

1997 • 1,970 citations

Direct binding of Smad3 and Smad4 to critical TGFbeta -inducible elements in the promoter of human plasminogen activator inhibitor-type 1gene

1998 • 1,763 citations

Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells

1985 • 1,687 citations

Mutations in myostatin (GDF8) in Double-Muscled Belgian Blue and Piedmontese Cattle

1997 • 1,159 citations

Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity.

1980 • 903 citations

Latent high molecular weight complex of transforming growth factor beta 1. Purification from human platelets and structural characterization.

1988 • 648 citations

Latent transforming growth factor-beta from human platelets. A high molecular weight complex containing precursor sequences.

1988 • 548 citations

Characterization of a membrane receptor for transforming growth factor-beta in normal rat kidney fibroblasts.

1984 • 477 citations

TGF-β1 binding protein: A component of the large latent complex of TGF-β1 with multiple repeat sequences

1990 • 447 citations

Physicochemical Activation of Recombinant Latent Transforming Growth Factor-beta's 1, 2, and 3

1990 • 343 citations

Recombinant latent transforming growth factor beta 1 has a longer plasma half-life in rats than active transforming growth factor beta 1, and a different tissue distribution.

1990 • 311 citations

Requirement for Activin a and Transforming Growth Factor--β1 Pro-Regions in Homodimer Assembly

1990 • 266 citations

Improved vectors for stable expression of foreign genes in mammalian cells by use of the untranslated leader sequence from EMC virus

1991 • 265 citations

Expression of growth/differentiation factor 11, a new member of the BMP/TGFβ superfamily during mouse embryogenesis

1999 • 231 citations

Identification and characterization of LTBP-2, a novel latent transforming growth factor-beta-binding protein.

1994 • 192 citations

Proteolytic processing of mullerian inhibiting substance produces a transforming growth factor-beta-like fragment.

1988 • 190 citations

Expression and Characterization of Bone Morphogenetic Protein-2 in Chinese Hamster Ovary Cells

1992 • 188 citations

The pro domain of pre-pro-transforming growth factor .beta.1 when independently expressed is a functional binding protein for the mature growth factor

1990 • 185 citations

Bone morphogenetic protein-9 binds to liver cells and stimulates proliferation.

1995 • 176 citations

A Novel BMP Expressed in Developing Mouse Limb, Spinal Cord, and Tail Bud Is a Potent Mesoderm Inducer inXenopusEmbryos

1999 • 166 citations

Isolation of a Novel Latent Transforming Growth Factor-β Binding Protein Gene (LTBP-3)

1995 • 147 citations

The recombinant proregion of transforming growth factor beta1 (latency-associated peptide) inhibits active transforming growth factor beta1 in transgenic mice.

1996 • 147 citations

Preferred sequence requirements for cleavage of pro-von Willebrand factor by propeptide-processing enzymes

1992 • 130 citations

Identification and Characterization of a New Latent Transforming Growth Factor-β-binding Protein, LTBP-4

1998 • 128 citations

Recombinant TGF-β1 is Synthesized as a Two-Component Latent Complex that Shares Some Structural Features with the Native Platelet Latent TGF-β1 Complex

1989 • 108 citations

Osteogenic Protein-1 (OP-1) Expression and Processing in Chinese Hamster Ovary Cells: Isolation of a Soluble Complex Containing the Mature and Pro-Domains of OP-1

1994 • 85 citations

Fetal Development of the Double Muscled Condition in Cattle

1974 • 68 citations

Osteogenic protein-1 regulates L1 and neural cell adhesion molecule gene expression in neural cells.

1993 • 48 citations

Comparative aspects of muscle fiber types in fetuses of the normal and "double-muscled" cattle.

1974 • 42 citations

Automated Protein Preparation Techniques Using a Digest Robot

1997 • 42 citations

High-Level Expression of TGF-β2 and the TGF-β2(414) Precursor in Chinese Hamster Ovary Cells

1990 • 26 citations

Crystallization and preliminary X‐ray analysis of recombinant human transforming growth factor β2

1992 • 22 citations