Paroxetine

The Cross National Epidemiology of obsessive-compulsive disorder

1994 • 663 citations

Pharmacological characterization of selective serotonin reuptake inhibitors (SSRIs)

1994 • 488 citations

The cross national epidemiology of obsessive compulsive disorder. The Cross National Collaborative Group.

1994 • 486 citations

The effect of selective serotonin re‐uptake inhibitors on cytochrome P4502D6 (CYP2D6) activity in human liver microsomes.

1992 • 456 citations

Phenelzine vs Atenolol in Social Phobia

1992 • 440 citations

Cognitive-Behavioral and Pharmacological Treatments of Social Phobia

1991 • 408 citations

Clinically Relevant Pharmacology of Selective Serotonin Reuptake Inhibitors

1997 • 357 citations

Paroxetine

1991 • 328 citations

Dose-dependent inhibition of CYP1A2, CYP2C19 and CYP2D6 by citalopram, fluoxetine, fluvoxamine and paroxetine

1996 • 314 citations

Clinical Pharmacokinetics of Selective Serotonin Reuptake Inhibitors

1993 • 300 citations

Serotonin Reuptake Inhibitor Withdrawal

1996 • 299 citations

Treatment of Social Phobia With Clonazepam and Placebo

1993 • 275 citations

Paroxetine in the Treatment of Panic Disorder a Randomised, Double-Blind, Placebo-Controlled Study

1995 • 267 citations

A review of the metabolism and pharmacokinetics of paroxetine in man

1989 • 259 citations

Presynaptic and postsynaptic modifications of the serotonin system by long-term administration of antidepressant treatments. An in vivo electrophysiologic study in the rat.

1991 • 251 citations

Biochemical effects of the antidepressant paroxetine, a specific 5-hydroxytryptamine uptake inhibitor

1987 • 245 citations

Paroxetine versus Clomipramine in the Treatment of Obsessive–Compulsive Disorder

1996 • 234 citations

What Price Depression?

1994 • 226 citations

Double-Blind, Fixed-Dose, Placebo-Controlled Study of Paroxetine in the Treatment of Panic Disorder

1998 • 223 citations

The Serotonin Reuptake Inhibitor Paroxetin Is Superior to the Noradrenaline Reuptake Inhibitor Maprotiline in the Treatment of Premenstrual Syndrome

1995 • 210 citations

Paroxetine is better than placebo in relapse prevention and the prophylaxis of recurrent depression

1993 • 190 citations

Inhibition by paroxetine of desipramine metabolism in extensive but not in poor metabolizers of sparteine

1993 • 189 citations

A Comparison of Paroxetine, Imipramine and Placebo in Depressed Out-patients

1991 • 175 citations

A comparison of the post‐marketing safety of four selective serotonin re‐uptake inhibitors including the investigation of symptoms occurring on withdrawal

1996 • 174 citations

Lifetime Risk of Depression

1994 • 161 citations

Clomipramine Administered during the Luteal Phase Reduces the Symptoms of Premenstrual Syndrome: A Placebo-Controlled Trial

1993 • 159 citations

A comparison of paroxetine, clomipramine and placebo in the treatment of panic disorder

1997 • 156 citations

Serum levels of clozapine and norclozapine in patients treated with selective serotonin reuptake inhibitors

1996 • 150 citations

Pharmacokinetics of the selective serotonin reuptake inhibitor paroxetine: Nonlinearity and relation to the sparteine oxidation polymorphism

1992 • 150 citations

Long‐term evaluation of paroxetine, clomipramine and placebo in panic disorder

1997 • 141 citations

Nefazodone

1997 • 141 citations

Paroxetine in the Treatment of Generalized Social Phobia

1996 • 138 citations

Pharmacokinetic Drug Interactions of New Antidepressants: A Review of the Effects on the Metabolism of Other Drugs

1997 • 132 citations

The role of cytochrome P4502D6 in the metabolism of paroxetine by human liver microsomes.

1992 • 130 citations

The effects of paroxetine and nefazodone on sleep: a placebo controlled trial

1996 • 124 citations

Double-blind controlled trial of sertraline versus paroxetine in the treatment of delusional depression

1996 • 120 citations

Further evidence for the importance of 5-HT1A autoreceptors in the action of selective serotonin reuptake inhibitors

1994 • 117 citations

Antidepressants in the Management of Chronic Pain Syndromes

1990 • 117 citations

Inhibition of median and dorsal raphe neurones following administration of the selective serotonin reuptake inhibitor paroxetine

1995 • 116 citations

Selective Serotonin Reuptake Inhibitors: Pharmacologic Profiles and Potential Therapeutic Distinctions

1994 • 116 citations

A double‐blind, comparative, multicentre study comparing paroxetine with fluoxetine in depressed patients

1993 • 115 citations

The serotonin syndrome associated with paroxetine, an over-the-counter cold remedy, and vascular disease

1994 • 114 citations

Reduction of suicidal thoughts with paroxetine in comparison with reference antidepressants and placebo

1995 • 109 citations

Optimal dose regimen for paroxetine.

1992 • 107 citations

Pharmacokinetics of Selective Serotonin Reuptake Inhibitors: Clinical Relevance

1996 • 105 citations

Comparison of SPECT applications in neurology and psychiatry.

1992 • 105 citations

A Double-Blind Study of Paroxetine Compared With Fluoxetine in Geriatric Patients With Major Depression

1993 • 98 citations

The safety profile of paroxetine.

1992 • 95 citations

Metabolic pathway of paroxetine in animals and man and the comparative pharmacological properties of its metabolites

1989 • 93 citations

Acute and subchronic effects of paroxetine 20 and 40 mg on actual driving, psychomotor performance and subjective assessments in healthy volunteers

1995 • 93 citations

Acute, Subchronic and Withdrawal Sleep EEG Changes During Treatment With Paroxetine and Amitriptyline: A Double-Blind Randomized Trial in Major Depression

1995 • 91 citations

Sleep Laboratory Studies on the Single-Dose Effects of Serotonin Reuptake Inhibitors Paroxetine and Fluoxetine on Human Sleep and Awakening Qualities

1991 • 90 citations

A Double-Blind Comparison of Fluvoxamine and Paroxetine in the Treatment of Depressed Outpatients

1997 • 89 citations

Two combined, multicenter double-blind studies of paroxetine and doxepin in geriatric patients with major depression.

1992 • 86 citations

Antidepressant Pharmacotherapy: Economic Evaluation of Fluoxetine, Paroxetine and Sertraline in a Health Maintenance Organization

1995 • 85 citations

A multicenter double-blind comparison of nefazodone and paroxetine in the treatment of outpatients with moderate-to-severe depression.

1996 • 83 citations

Basic advances in serotonin pharmacology.

1992 • 81 citations

Paroxetine plasma levels: lack of correlation with efficacy or adverse events

1989 • 79 citations

The Effect of Amitriptyline, Doxepin, Fluvoxamine, and Paroxetine Treatment on Heart Rate Variability

1994 • 77 citations

No influence of the antidepressant paroxetine on carbamazepine, valproate and phenytoin

1991 • 77 citations

A study comparing paroxetine placebo and imipramine in depressed patients

1993 • 76 citations

A Double-Blind, Randomized, Fluoxetine-Controlled, Multicenter Study of Paroxetine in the Treatment of Depression

1993 • 75 citations

Paroxetine as a Treatment for Premenstrual Dysphoric Disorder

1996 • 73 citations

Evaluation of the potential for interactions of paroxetine with diazepam, cimetidine, warfarin, and digoxin

1989 • 72 citations

A Double-Blind, Multicenter Study in Primary Care Comparing Paroxetine and Clomipramine in Patients With Depression and Associated Anxiety

1997 • 71 citations

Selective Serotonin Reuptake Inhibitors

1997 • 69 citations

5-HT1A autoreceptors and the mode of action of selective serotonin reuptake inhibitors (SSRI)

1995 • 69 citations

A Multicenter Double-Blind Trial of Paroxetine Versus Amitriptyline in Depressed Inpatients

1994 • 66 citations

Sulpiride and Paroxetine in the Treatment of Chronic Tension‐Type Headache. An Explanatory Double‐Blind Trial

1994 • 61 citations

The effects of paroxetine and other antidepressants in combination with alcohol in psychomotor activity related to car driving

1988 • 61 citations

Cost-effectiveness of antidepressant treatment reassessed

1997 • 59 citations

Multicenter double blind study of paroxetine and amitriptyline in elderly depressed inpatients

1995 • 59 citations

TARGETED PHARMACOTHERAPY IN DEPRESSION MANAGEMENT: COMPARATIVE PHARMACOKINETICS OF FLUOXETINE, PAROXETINE, AND SERTRALINE

1994 • 58 citations

The effects of paroxetine, alone and in combination with alcohol on psychomotor performance and cognitive function in the elderly

1992 • 56 citations

The pharmacokinetics of paroxetine in renal impairment

1989 • 55 citations

Adverse Events After the Abrupt Discontinuation of Paroxetine

1995 • 54 citations

Effect of clomipramine on premenstrual syndrome

1990 • 54 citations

Paroxetine in Social Phobia

1996 • 53 citations

Panic disorder: diagnosis, epidemiology, and clinical course.

1996 • 53 citations

A Double-Blind Comparison of Paroxetine With Imipramine in the Long-Term Treatment of Depression

1993 • 51 citations

Double-Blind Multicenter Study of Paroxetine and Amitriptyline in Depressed Inpatients

1993 • 50 citations

Paroxetine shifts imipramine metabolism

1996 • 50 citations

Paroxetine in the Treatment of Chronic Daily Headache

1994 • 50 citations

Misuse of the face-hand test for psychogenic neurologic deficits.

1994 • 49 citations

The pharmacokinetics of paroxetine in the elderly

1989 • 46 citations

Paroxetine versus placebo: a double-blind comparison in depressed patients.

1992 • 45 citations

Serotonin Syndrome Associated With Nefazodone and Paroxetine

1997 • 43 citations

The Safety of Concomitant Use of Sumatriptan and Antidepressant Treatments

1995 • 42 citations

Paroxetine

1992 • 42 citations

A Double-Blind Multicentre Study of Paroxetine and Amitriptyline in Depressed Outpatients

1992 • 41 citations

Sleep and Paroxetine

1992 • 41 citations

Paroxetine and imipramine in the treatment of depressive patients in psychiatric practice

1992 • 41 citations

Direct Cost of Depression: Analysis of Treatment Costs of Paroxetine versus Imipramine in Canada

1995 • 38 citations

Safety and tolerability of combined treatment with moclobemide and SSRIs

1996 • 35 citations

Pharmacokinetics of paroxetine in patients with cirrhosis

1991 • 35 citations

Guidelines for the long-term treatment of depression.

1994 • 34 citations

Paroxetine in the Elderly: A Comparative Meta-Analysis against Standard Antidepressant Pharmacotherapy

1995 • 34 citations

Cost Analysis of Paroxetine versus Imipramine in Major Depression

1995 • 34 citations

Paroxetine and amitriptyline in the treatment of depression in general practice

1996 • 33 citations

A 12‐week double‐blind multi‐centre study of paroxetine and imipramine in hospitalized depressed patients

1994 • 32 citations

Paroxetine

1992 • 31 citations

TREATMENT OF MAJOR DEPRESSION IN GENERAL PRACTICE: A DOUBLE‐BLIND COMPARISON OF PAROXETINE AND LOFEPRAMINE

1996 • 30 citations

Potential Withdrawal Syndrome Associated with Ssri Discontinuation

1995 • 30 citations

A Double-blind Study Comparing Paroxetine and Maprotiline in Depressed Outpatients

1997 • 28 citations

The pharmacokinetics of paroxetine in patients with liver cirrhosis

1989 • 27 citations

Paroxetine

1997 • 26 citations

SSRI differntiation: Pharmacology and pharmacokinetics

1995 • 25 citations

A Review of the Psychomotor Effects of Paroxetine

1992 • 24 citations

Antidepressant pharmacotherapy: cost comparison of SSRIs and TCAs

1994 • 23 citations

Controlled comparison of paroxetine and fluvoxamine in major depression

1994 • 23 citations

Cardiovascular Effects of Antidepressants

1992 • 23 citations

The psychomotor effects of paroxetine alone and in combination with haloperidol, amylobarbitone, oxazepam, or alcohol

1989 • 23 citations

Absorption of paroxetine under various dietary conditions and following antacid intake

1989 • 22 citations

Moclobemide and specific serotonin re‐uptake inhibitor combination treatment of resistant anxiety and depressive disorders

1995 • 22 citations

A Double-Blind, Multicentre Study of Paroxetine and Maprotiline in Major Depression

1996 • 21 citations

Effect of paroxetine, a selective 5-hydroxytryptamine uptake inhibitor, on β-adrenoceptors in rat brain: Autoradiographic and functional studies

1991 • 21 citations

Lack of an Interaction Between Sumatriptan and Selective Serotonin Reuptake Inhibitors

1995 • 19 citations

Paroxetine-molindone interaction.

1995 • 19 citations

The effects of paroxetine and other antidepressants in combination with alcohol on psychomotor activity related to car driving

1989 • 18 citations

A review of the psychomotor effects of paroxetine

1997 • 18 citations

Effect of prolonged 5-hydroxytryptamine uptake inhibition by paroxetine on cortical β1 and β2-adrenoceptors in rat brain

1990 • 18 citations

A comparison of five commonly prescribed antidepressants with particular reference to their behavioural toxicity

1993 • 17 citations

Tolerability of combined treatment with lithium and paroxetine: 19 cases treated under open conditions

1994 • 16 citations

PEM report number 6. Paroxetine

1993 • 15 citations

Placebo‐Controlled trial of paroxetine in depressive illness

1993 • 14 citations

The Effect of Paroxetine and Dothiepin on Subjective Sleep in Depressed Patients

1997 • 10 citations

SSRIs: Well tolerated treatment for depression

1994 • 7 citations

Optimum Treatment of Panic Disorder

1994 • 4 citations

Setting New Standards for the Pharmacological Treatment of Panic Disorder

1997 • 4 citations

Deleted Work

1955 • 0 citations