Effect of evolution on the kinetic properties of enzymes

A Linear Steady-State Treatment of Enzymatic Chains. General Properties, Control and Effector Strength

1974 • 1,378 citations

Evolution of enzyme function and the development of catalytic efficiency

1976 • 604 citations

Metabolic regulation and mathematical models

1978 • 491 citations

Glycolytic Control Mechanisms

1965 • 373 citations

Catalysis, binding and enzyme-substrate complementarity

1974 • 222 citations

Evolution of catalytic proteins

1984 • 136 citations

Natural selection and the Michaelis constant

1975 • 93 citations

The effect of natural selection on enzymic catalysis

1976 • 89 citations

The evolution of enzyme kinetic power

1984 • 46 citations

Evolution of enzyme catalytic power. Characteristics of optimal catalysis evaluated for the simplest plausible kinetic model

1977 • 41 citations

Generalized microscopic reversibility, kinetic co-operativity of enzymes and evolution

1978 • 28 citations

The pre-eminence of kcat. in the manifestation of optimal enzymic activity delineated by using the Briggs-Haldane two-step irreversible kinetic model

1976 • 23 citations

Kinetic power: Basis of enzyme efficiency, specificity and evolution

1988 • 10 citations