Two Distinct Coactivators, DRIP/Mediator and SRC/p160, Are Differentially Involved in Vitamin D Receptor Transactivation during Keratinocyte Differentiation

Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

1996 • 8,994 citations

Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning

1997 • 1,149 citations

Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937.

1996 • 922 citations

Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex

1999 • 733 citations

The SRC family of nuclear receptor coactivators

2000 • 515 citations

A novel protein complex that interacts with the vitamin D₃ receptor in a ligand-dependent manner and enhances VDR transactivation in a cell-free system

1998 • 391 citations

Mechanisms of gene regulation by vitamin D3 receptor: a network of coactivator interactions

2000 • 321 citations

Involvement of the TRAP220 Component of the TRAP/SMCC Coactivator Complex in Embryonic Development and Thyroid Hormone Action

2000 • 287 citations

Mediator complexes and transcription

2001 • 278 citations

The TRAP/SMCC/Mediator complex and thyroid hormone receptor function

2001 • 250 citations

The DRIP Complex and SRC-1/p160 Coactivators Share Similar Nuclear Receptor Binding Determinants but Constitute Functionally Distinct Complexes

2000 • 202 citations

Lack of the Vitamin D Receptor is Associated with Reduced Epidermal Differentiation and Hair Follicle Growth

2002 • 188 citations

Identification of a vitamin D-response element in the rat calcidiol (25-hydroxyvitamin D3) 24-hydroxylase gene.

1994 • 164 citations

The Calcium Sensing Receptor and Its Alternatively Spliced Form in Keratinocyte Differentiation

1998 • 157 citations

Metabolic and cellular analysis of alopecia in vitamin D receptor knockout mice

2001 • 139 citations

1,25-Dihydroxyvitamin D3 potentiates the keratinocyte response to calcium.

1994 • 122 citations

The USA-Derived Transcriptional Coactivator PC2 Is a Submodule of TRAP/SMCC and Acts Synergistically with Other PCs

2000 • 122 citations

The Calcium Sensing Receptor and Its Alternatively Spliced Form in Murine Epidermal Differentiation

2000 • 117 citations

Retinoic acid induces transglutaminase activity but inhibits cornification of cultured epidermal cells.

1982 • 93 citations

Requirement of an AP-1 Site in the Calcium Response Region of the Involucrin Promoter

2000 • 81 citations

Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase

2002 • 81 citations

Competition between Thyroid Hormone Receptor-associated Protein (TRAP) 220 and Transcriptional Intermediary Factor (TIF) 2 for Binding to Nuclear Receptors

1999 • 76 citations

Evidence for Separate Control Mechanisms at the Message, Protein, and Enzyme Activation Levels for Transglutaminase During Calcium-Induced Differentiation of Normal and Transformed Human Keratinocytes

1996 • 70 citations

Binding of Liganded Vitamin D Receptor to the Vitamin D Receptor Interacting Protein Coactivator Complex Induces Interaction with RNA Polymerase II Holoenzyme

2000 • 59 citations

Identification and isolation of three proteasome subunits and their encoding genes from Trypanosoma brucei

1999 • 30 citations

1,25(OH)2D3-modulated calcium induced keratinocyte differentiation.

1996 • 22 citations

The Human Homologue of Drosophila TRF-proximal Protein Is Associated with an RNA Polymerase II-SRB Complex

1999 • 15 citations