Rate of Progression of Alzheimer's Disease Is Associated With Genetic Risk

Clinical diagnosis of Alzheimer's disease

1984 • 27,279 citations

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

1993 • 8,888 citations

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

1991 • 4,533 citations

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.

1993 • 4,145 citations

The Association Between Quantitative Measures of Dementia and of Senile Change in the Cerebral Grey Matter of Elderly Subjects

1968 • 4,041 citations

Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's disease

1993 • 3,693 citations

Diagnosis of Alzheimer's Disease

1985 • 2,482 citations

The Clinical Diagnosis of Alzheimer's Disease

1987 • 1,381 citations

Genetic Linkage Evidence for a Familial Alzheimer's Disease Locus on Chromosome 14

1992 • 941 citations

Linkage studies in familial Alzheimer disease: evidence for chromosome 19 linkage.

1991 • 762 citations

Heterogeneity in dementia of the Alzheimer type: Evidence of subgroups

1985 • 507 citations

Apolipoprotein E4 allele in a population–based study of early–onset Alzheimer's disease

1994 • 449 citations

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD)

1993 • 422 citations

Skewness in Commingled Distributions

1976 • 337 citations

Mapping of a gene predisposing to early–onset Alzheimer's disease to chromosome 14q24.3

1992 • 332 citations

[Apolipoprotein E polymorphism and Alzheimer disease].

1996 • 302 citations

Clinical subtypes of dementia of the Alzheimer type

1985 • 299 citations

A locus for familial early–onset Alzhelmer's disease on the long arm of chromosome 14, proximal to the α1–antichymotrypsin gene

1992 • 267 citations

Predictors of disease course in patients with probable Alzheimer's disease

1987 • 263 citations

Early‐onset Alzheimer's disease

1987 • 231 citations

Familial aggregation in Alzheimer's disease

1988 • 195 citations

Cognitive deficits of men and women with Alzheimer's disease

1994 • 172 citations

The Prognosis in Alzheimer's Disease

1990 • 154 citations

Comparison of rate of annual change of mental status score in four independent studies of patients with Alzheimer's disease

1988 • 144 citations

Age at Onset and Rate of Progression of Alzheimer's Disease

1987 • 119 citations

A comparison of familial and sporadic Alzheimer's disease

1993 • 119 citations

Factors associated with duration of survival in Alzheimer's disease

1985 • 101 citations

Dementia

1988 • 97 citations

Segregation analysis reveals evidence of a major gene for Alzheimer disease.

1991 • 81 citations

Rate of Progression of Alzheimer's Disease

1989 • 71 citations

The record of independent living

1986 • 70 citations

Duration of survival in senile dementia

1986 • 62 citations

Language disorder predicts familial Alzheimer's disease.

1981 • 61 citations

Interrater agreement for diagnosis of Alzheimer's disease

1994 • 45 citations

Deterioration on the blessed test in Alzheimer's disease: Longitudinal data and their implications for clinical trials and identification of subtypes

1992 • 40 citations

Estimating the probability for major gene Alzheimer disease.

1994 • 16 citations