Nitric oxide mediates interferon-gamma-induced hyperpermeability in cultured human intestinal epithelial monolayers

Nitric oxide as a secretory product of mammalian cells

1992 • 4,437 citations

Interferon-gamma directly affects barrier function of cultured intestinal epithelial monolayers.

1989 • 761 citations

Nitrate biosynthesis in man.

1981 • 677 citations

Nitrogen Oxide Levels in Patients After Trauma and During Sepsis

1991 • 609 citations

Nitric oxide synthase activity in ulcerative colitis and Crohn's disease

1993 • 468 citations

Amelioration of chronic ileitis by nitric oxide synthase inhibition.

1993 • 416 citations

Increased nitric oxide synthesis in ulcerative colitis

1993 • 347 citations

Loosening tight junctions. Lessons from the intestine.

1989 • 329 citations

Increased Intestinal Permeability Associated With Infection in Burn Patients

1988 • 315 citations

A Single Dose of Endotoxin Increases Intestinal Permeability in Healthy Humans

1988 • 302 citations

Intestinal permeability is increased in burn patients shortly after injury.

1990 • 287 citations

L-arginine pathway in the sepsis syndrome

1993 • 242 citations

L-arginine

1995 • 208 citations

Cytokine-induced expression of a nitric oxide synthase in rat renal tubule cells.

1993 • 184 citations

IL-4 directly modulates function of a model human intestinal epithelium.

1994 • 181 citations

Intestinal Permeability After Severe Trauma and Hemorrhagic Shock Is Increased Without Relation to Septic Complications

1993 • 159 citations

Inactivation of nitric oxide synthase after prolonged incubation of mouse macrophages with IFN-gamma and bacterial lipopolysaccharide.

1994 • 138 citations

An in vitro model for the analysis of intestinal brush border assembly I. Ultrastructural analysis of cell contact-induced brush border assembly in Caco-2BBe cells

1993 • 131 citations

Effects of nitric oxide synthase inhibition on the pathophysiology observed in a model of chronic granulomatous colitis.

1994 • 130 citations

Role of nitric oxide in the hemodynamic changes of sepsis

1993 • 124 citations

Increased gut permeability early after burns correlates with the extent of burn injury

1992 • 111 citations

Intestinal permeability in the critically ill

1992 • 110 citations

Small bowel and colonic permeability to 51Cr-EDTA in patients with active inflammatory bowel disease.

1988 • 92 citations

Cellular Localization of Inducible Nitric Oxide Synthase in Experimental Endotoxic Shock in the Rat

1994 • 90 citations

Detectable Colonic Nitrite Levels in Inflammatory Bowel Disease – Mucosal or Bacterial Malfunction?

1986 • 85 citations

Nitric oxide synthase activity, viability and cyclic GMP levels in rat colonic epithelial cells: effect of endotoxin challenge.

1994 • 62 citations

Expression of nitric oxide synthase by cytokines in vascular smooth muscle cells.

1994 • 51 citations

Endotoxin-stimulated alveolar macrophages impair lung epithelial Na+ transport by an L-Arg-dependent mechanism

1994 • 48 citations

Comparison of different measurements of intestinal permeability in inflammatory bowel disease.

1991 • 47 citations

Regulation of polyethylene glycol 400 intestinal permeability by endogenous and exogenous prostanoids. Influence of non-steroidal anti-inflammatory drugs.

1990 • 43 citations

Production of inflammatory cytokines in the intestinal lamina propria

1991 • 31 citations