Relationship between Human T Cell Functional Heterogeneity and Human T Cell Surface Molecules

The differentiation and function of human T lymphocytes

1980 • 1,548 citations

Monoclonal Antibodies Defining Distinctive Human T Cell Surface Antigens

1979 • 1,480 citations

Functional subclasses of T-lymphocytes bearing different Ly antigens. I. The generation of functionally distinct T-cell subclasses is a differentiative process independent of antigen.

1975 • 1,105 citations

Evolutionary conservation of surface molecules that distinguish T lymphocyte helper/inducer and cytotoxic/suppressor subpopulations in mouse and man

1981 • 871 citations

OKT3: A monoclonal anti-human T lymphocyte antibody with potent mitogenic properties

1980 • 718 citations

Further Characterization of the Human Inducer T Cell Subset Defined by Monoclonal Antibody

1979 • 610 citations

Clonal analysis of human cytotoxic T lymphocytes: T4+ and T8+ effector T cells recognize products of different major histocompatibility complex regions.

1982 • 600 citations

OKT3: a monoclonal anti-human T lymphocyte antibody with potent mitogenic properties.

1980 • 525 citations

Antigen recognition by human T lymphocytes is linked to surface expression of the T3 molecular complex

1982 • 494 citations

A Monoclonal Antibody with Selective Reactivity with Functionally Mature Human Thymocytes and All Peripheral Human T Cells

1979 • 456 citations

Surface phenotype of Japanese adult T-cell leukemia cells characterized by monoclonal antibodies

1981 • 417 citations

Regulation of Cellular and Humoral Immune Responses by T-cell Subclasses

1977 • 368 citations

Thymus-dependent membrane antigens in man: Inhibition of cell-mediated lympholysis by monoclonal antibodies to T _{H 2} antigen

1981 • 352 citations

Activation of human T lymphocyte subsets: helper and suppressor/cytotoxic T cells recognize and respond to distinct histocompatibility antigens.

1981 • 338 citations

Does OKT3 monoclonal antibody react with an antigen-recognition structure on human T cells?

1981 • 306 citations

Possible involvement of the OKT4 molecule in T cell recognition of class II HLA antigens. Evidence from studies of cytotoxic T lymphocytes specific for SB antigens.

1982 • 306 citations

Antibodies to membrane structures that distinguish suppressor/cytotoxic and helper T lymphocyte subpopulations block the mixed leukocyte reaction in man.

1981 • 304 citations

Surface phenotype of Japanese adult T-cell leukemia cells characterized by monoclonal antibodies

1981 • 298 citations

Functional analysis of human T cell subsets defined by monoclonal antibodies. I. Collaborative T-T interactions in the immunoregulation of B cell differentiation.

1980 • 296 citations

Monoclonal antibodies OKT 11 and OKT 11A have pan‐T reactivity and block sheep erythrocyte “receptors”

1982 • 295 citations

Functional analysis of human T cell subsets defined by monoclonal antibodies. IV. Induction of suppressor cells within the OKT4+ population.

1981 • 245 citations

Mechanism of T Cell Activation: Role and Functional Relationship of HLA‐DR Antigens and Interleukins

1982 • 244 citations

A monoclonal antibody blocking human T cell function

1980 • 239 citations

Long-term human cytolytic T-cell lines allospecific for HLA-DR6 antigen are OKT4+.

1982 • 237 citations

Significance of Lyt phenotypes: Lyt2 antibodies block activities of T cells that recognize class 1 major histocompatibility complex antigens regardless of their function.

1981 • 234 citations

Contrasuppression. A novel immunoregulatory activity.

1981 • 227 citations

Two Functionally Distinct Subpopulations of Human T Cells That Collaborate in the Generation of Cytotoxic Cells Responsible for Cell-Mediated Lympholysis

1978 • 206 citations

Complexity of the human T lymphocyte-specific cell surface antigen T3.

1982 • 170 citations

Phenotypic and functional analysis of leukemic cells from 16 patients with adult T-cell leukemia/lymphoma

1983 • 166 citations

Immunologic regulation of experimental cutaneous leishmaniasis. V. Characterization of effector and specific suppressor T cells.

1982 • 163 citations

Functional analysis of human T cell subsets defined by monoclonal antibodies. V. Suppressor cells within the activated OKT4+ population belong to a distinct subset.

1982 • 162 citations

Detection, isolation, and functional characterization of two human T-cell subclasses bearing unique differentiation antigens.

1977 • 154 citations

Suppression of human T-cell mitogenesis and E-rosette formation by the monoclonal antibody OKT11A.

1981 • 151 citations

Characterization of T cell surface glycoproteins T1 and T3 present on all human peripheral T lymphocytes and functionally mature thymocytes

1981 • 147 citations

Is the E receptor on human T lymphocytes a "negative signal receptor"?

1982 • 137 citations

Specificity of OKT4+ cytotoxic T lymphocyte clones.

1982 • 136 citations

Surface markers of cloned human T cells with various cytolytic activities.

1981 • 132 citations

Cellular origin and interactions involved in gamma-interferon production induced by OKt3 monoclonal antibody.

1982 • 129 citations

Regulation of B cell differentiation by T cell subsets defined with monoclonal OKT4 and OKT8 antibodies in human cord blood.

1981 • 122 citations

Establishment of human T lymphocyte clones highly cytotoxic for an EBV-transformed B cell line in serum-free medium: isolation of clones that differ in phenotype and specificity.

1982 • 117 citations

Inhibition of specific cell-mediated cytotoxicity by monoclonal antibodies to human T cell antigens

1981 • 105 citations

In vitro effects of 4-hydroperoxycyclophosphamide on human immunoregulatory T subset function. I. Selective effects on lymphocyte function in T-B cell collaboration.

1982 • 104 citations

The Lyt phenotype of a long‐term allospecific T cell line. Both helper and killer activities to IA are mediated by Ly‐1 cells

1981 • 93 citations

The T4 surface antigen is involved in the induction of helper function.

1984 • 77 citations

Five epitopes of a differentiation antigen on human inducer T cells distinguished by monoclonal antibodies

1983 • 69 citations

Functional analysis of human T cell subsets defined by monoclonal antibodies. III. Regulation of helper factor production by T cell subsets.

1981 • 64 citations

T cells may express multiple activities: specific allohelp, cytolysis, and delayed-type hypersensitivity are expressed by a cloned T-cell line.

1981 • 51 citations

Functional analysis of human T cell subsets defined by monoclonal antibodies. II. Collaborative T-T interactions in the generation of TNP-altered-self-reactive cytotoxic T lymphocytes.

1981 • 45 citations

surface markers of mono‐and multi‐functional mixed leukocyte culture‐derived T cell clones in man

1982 • 42 citations

OT-CLL: a human T cell chronic lymphocytic leukemia that produces IL 2 in high titer.

1982 • 30 citations

Functional analysis of human T cell subsets defined by monoclonal antibodies. VI. Distinct and opposing immunoregulatory functions within the OKT8+ population.

1984 • 23 citations