Retiming the failing heart: principles and current clinical status of cardiac resynchronization

The Effect of Spironolactone on Morbidity and Mortality in Patients with Severe Heart Failure

1999 • 8,588 citations

The Effect of Spironolactone on Morbidity and Mortality in Patients with Severe Heart Failure

2000 • 2,991 citations

Effects of Multisite Biventricular Pacing in Patients with Heart Failure and Intraventricular Conduction Delay

2001 • 2,717 citations

Effect of losartan compared with captopril on mortality in patients with symptomatic heart failure: randomised trial—the Losartan Heart Failure Survival Study ELITE II

2000 • 1,956 citations

Long-term ACE-inhibitor therapy in patients with heart failure or left-ventricular dysfunction: a systematic overview of data from individual patients

2000 • 1,567 citations

Effect of Pacing Chamber and Atrioventricular Delay on Acute Systolic Function of Paced Patients With Congestive Heart Failure

1999 • 1,164 citations

β-Adrenergic Receptor Blockade in Chronic Heart Failure

2000 • 1,020 citations

Improved Left Ventricular Mechanics From Acute VDD Pacing in Patients With Dilated Cardiomyopathy and Ventricular Conduction Delay

1999 • 989 citations

Left Ventricular or Biventricular Pacing Improves Cardiac Function at Diminished Energy Cost in Patients With Dilated Cardiomyopathy and Left Bundle-Branch Block

2000 • 764 citations

Mapping of regional myocardial strain and work during ventricular pacing: experimental study using magnetic resonance imaging tagging

1999 • 659 citations

Evaluation of Different Ventricular Pacing Sites in Patients With Severe Heart Failure

1997 • 656 citations

Acute hemodynamic effects of biventricular DDD pacing in patients with end-stage heart failure

1998 • 539 citations

Clinical determinants of mortality in chronic congestive heart failure secondary to idiopathic dilated or to ischemic cardiomyopathy

1987 • 465 citations

Multisite Pacing for End‐Stage Heart Failure: Early Experience

1996 • 446 citations

Mechanism of hemodynamic improvement by dual-chamber pacing for severe left ventricular dysfunction: An acute Doppler and catheterization hemodynamic study

1995 • 404 citations

Redistribution of myocardial fiber strain and blood flow by asynchronous activation

1990 • 383 citations

Effects of dual-chamber pacing with short atrioventricular delay in dilated cardiomyopathy

1992 • 381 citations

Predictors of Systolic Augmentation From Left Ventricular Preexcitation in Patients With Dilated Cardiomyopathy and Intraventricular Conduction Delay

2000 • 375 citations

Ventricular contraction abnormalities in dilated cardiomyopathy: effect of biventricular pacing to correct interventricular dyssynchrony

2000 • 352 citations

Permanent Left Ventricular Pacing With Transvenous Leads Inserted Into The Coronary Veins

1998 • 347 citations

Differential Effects of β-Blockers in Patients With Heart Failure

2000 • 342 citations

Relative importance of activation sequence compared to atrioventricular synchrony in left ventricular function

1991 • 336 citations

Heart failure management using implantable devices for ventricular resynchronization: Comparison of medical therapy, pacing, and defibrillation in chronic heart failure (COMPANION) trial

2000 • 330 citations

Natural history of abnormal conduction and its relation to prognosis in patients with dilated cardiomyopathy

1996 • 286 citations

Electrocardiographic predictive factors of long-term clinical improvement with multisite biventricular pacing in advanced heart failure

1999 • 282 citations

Mapping propagation of mechanical activation in the paced heart with MRI tagging

1999 • 279 citations

Dual-chamber pacing with a short atrioventricular delay in congestive heart failure: A randomized study

1995 • 259 citations

Biventricular pacing diminishes the need for implantable cardioverter defibrillator therapy

2000 • 258 citations

Results of atrioventricular synchronous pacing with optimized delay in patients with severe congestive heart failure

1995 • 238 citations

Hemodynamic importance of preserving the normal sequence of ventricular activation in permanent cardiac pacing

1995 • 230 citations

Optimal right ventricular pacing site in chronically implanted patients

1999 • 208 citations

Effect of alteration of left ventricular activation sequence on the left ventricular end-systolic pressure-volume relation in closed-chest dogs.

1985 • 205 citations

Transvenous biventricular pacing for heart failure: can the obstacles be overcome?

1999 • 197 citations

Serial electrocardiographic changes in idiopathic dilated cardiomyopathy confirmed at necropsy

1988 • 195 citations

Influence of pacing site on canine left ventricular contraction

1986 • 191 citations

A prolonged QRS duration on surface electrocardiogram is a specific indicator of left ventricular dysfunction

1998 • 186 citations

Doppler myocardial imaging in patients with heart failure receiving biventricular pacing treatment

2001 • 172 citations

Acute Effects of Intraoperative Multisite Ventricular Pacing on Left Ventricular Function and Activation/Contraction Sequence in Patients with Depressed Ventricular Function

1998 • 169 citations

Biventricular Pacing Decreases Sympathetic Activity Compared With Right Ventricular Pacing in Patients With Depressed Ejection Fraction

2000 • 166 citations

Biventricular pacing in end-stage heart failure improves functional capacity and left ventricular function.

2000 • 163 citations

Rationale and design of a randomized clinical trial to assess the safety and efficacy of cardiac resynchronization therapy in patients with advanced heart failure: The Multicenter InSync Randomized Clinical Evaluation (MIRACLE)

2000 • 159 citations

A pilot experience with permanent biventricular pacing to treat advanced heart failure

2000 • 148 citations

Load-dependent relaxation with late systolic volume steps: servo-pump studies in the intact canine heart.

1987 • 147 citations

Comparative effects of permanent biventricular pacing for refractory heart failure in patients with stable sinus rhythm or chronic atrial fibrillation

2000 • 146 citations

Alteration of left ventricular performance by left bundle branch block simulated with atrioventricular sequential pacing

1984 • 125 citations

Left Bundle Branch Block

1971 • 121 citations

Usefulness of suppression of ventricular arrhythmia by biventricular pacing in severe congestive cardiac failure

2000 • 119 citations

Nature of ventricular activation in patients with dilated cardiomyopathy: evidence for bilateral bundle branch block.

1994 • 112 citations

Mechanical Dyssynchrony in Dilated Cardiomyopathy With Intraventricular Conduction Delay as Depicted by 3D Tagged Magnetic Resonance Imaging

2000 • 109 citations

Differing effects of right ventricular pacing and left bundle branch block on left ventricular function.

1993 • 108 citations

Transvenous left ventricular lead implantation with the EASYTRAK lead system: the European experience

2000 • 104 citations

Comparison of the Effects of Right Atrial, Right Ventricular Apex and Atrioventricular Sequential Pacing on Myocardial Oxygen Consumption and Cardiac Efficiency: A Laboratory Investigation*

1988 • 101 citations

Mid‐term Follow‐Up of Endocardial Biventricular Pacing

2000 • 99 citations

Cardiac pacing in heart failure patients with left bundle branch block: impact of pacing site for optimizing left ventricular resynchronization.

2000 • 97 citations

What is the ideal study design for evaluation of treatment for heart failure?: Insights from trials assessing the effect of ACE inhibitors on exercise capacity

1996 • 96 citations

Acute Hemodynamic Improvement by Pacing in Patients with Severe Congestive Heart Failure

1997 • 95 citations

Different effects of abnormal activation and myocardial disease on left ventricular ejection and filling times

2000 • 85 citations

Effects of timing of atrial systole on LV filling and mitral valve closure: computer and dog studies

1985 • 76 citations

Reduction of hospital days by biventricular pacing

2000 • 70 citations

Left bundle branch block: A predictor of poor left ventricular function in coronary artery disease

1983 • 60 citations

The Effects of Ventricular Pacing on Left Ventricular Geometry, Function, Myocardial Oxygen Consumption, and Efficiency of Contraction in Conscious Dogs

1998 • 59 citations

A Method for Permanent Transvenous Left Ventricular Pacing

1998 • 59 citations

The InSync Italian Registry : analysis of clinical outcome and considerations on the selection of candidates to left ventricular resynchronization

2000 • 56 citations

Cardiac resynchronization: Materials, technique and results. The InSync Italian Registry

2000 • 56 citations

Discussion

1998 • 54 citations

An Even More Physiological Pacing: Changing the Sequence of Ventricular Activation

1983 • 54 citations

Effects of asynchrony on myocardial relaxation at rest and during exercise in conscious dogs

1988 • 52 citations

Should stimulation site be tailored in the individual heart failure patient?

2000 • 50 citations

Diastolic "locking" of the mitral valve: the importance of atrial systole and intraventricular volume.

1983 • 48 citations

Left ventricular‐based pacing in patients with chronic heart failure: comparison of acute hemodynamic benefits according to underlying heart disease

2000 • 33 citations

Effects of left ventricular pacing on cardiac performance and on quality of life in patients with drug refractory heart failure

2000 • 28 citations

Chronic benefit as a result of pacing in congestive heart failure: Results of the path CHF trial

1999 • 27 citations

Arrhythmias in patients with mechanical ventricular dysfunction and myocardial stretch: role of mechano-electric feedback.

1998 • 23 citations

The use of a 'side-wire' permanent transvenous pacing electrode for left ventricular pacing

1999 • 20 citations

Damage induced arrhythmias: mechanisms and implications

2001 • 19 citations

Deleted Work

1955 • 0 citations