Pretreatment but not posttreatment with GYKI 52466 reduces functional deficits and neuronal damage after global ischemia in rats

Elevation of the Extracellular Concentrations of Glutamate and Aspartate in Rat Hippocampus During Transient Cerebral Ischemia Monitored by Intracerebral Microdialysis

1984 • 2,884 citations

Delayed neuronal death in the gerbil hippocampus following ischemia

1982 • 2,856 citations

Temporal profile of neuronal damage in a model of transient forebrain ischemia

1982 • 2,695 citations

The Excitatory Amino Acid Receptors: Their Classes, Pharmacology, and Distinct Properties in the Function of the Central Nervous System

1989 • 2,203 citations

2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a Neuroprotectant for Cerebral Ischemia

1990 • 1,125 citations

Selective vulnerability of the hippocampus in brain ischemia

1991 • 876 citations

Calcium-Permeable AMPA-Kainate Receptors in Fusiform Cerebellar Glial Cells

1992 • 413 citations

Switch in glutamate receptor subunit gene expression in CA1 subfield of hippocampus following global ischemia in rats.

1992 • 399 citations

GYKI 52466, a 2,3-benzodiazepine, is a highly selective, noncompetitive antagonist of AMPA/kainate receptor responses

1993 • 359 citations

Comparative Effect of Transient Global Ischemia on Extracellular Levels of Glutamate, Glycine, and γ‐Aminobutyric Acid in Vulnerable and Nonvulnerable Brain Regions in the Rat

1991 • 299 citations

Blockade of the AMPA receptor prevents CA1 hippocampal injury following severe but transient forebrain ischemia in adult rats

1991 • 253 citations

Ischemic Damage in Hippocampal CA1 is Dependent on Glutamate Release and Intact Innervation from CA3

1989 • 249 citations

The N-methyl-d-aspartate antagonists CGS 19755 and CPP reduce ischemic brain damage in gerbils

1988 • 246 citations

Neurobehavioral deficit due to ischemic brain damage limited to half of the CA1 sector of the hippocampus

1989 • 234 citations

The non-NMDA antagonists, NBQX and GYKI 52466, protect against cortical and striatal cell loss following transient global ischaemia in the rat

1992 • 201 citations

The anticonvulsant effect of the non-NMDA antagonists, NBQX and GYKI 52466, in mice

1991 • 188 citations

Global ischaemia: Hippocampal pathology and spatial deficits in the water maze

1994 • 170 citations

Protection by NMDA Antagonists against Selective Cell Loss following Transient Ischaemia

1990 • 162 citations

Relationship between brain damage and memory impairment in rats exposed to transient forebrain ischemia

1991 • 160 citations

Treatment with an AMPA Antagonist 12 Hours following Severe Normothermic Forebrain Ischemia Prevents CA₁ Neuronal Injury

1993 • 148 citations

Cerebroprotective effect of a non-N-methyl-D-aspartate antagonist, GYKI 52466, after focal ischemia in the rat.

1992 • 145 citations

Electrophysiological studies with a 2,3-benzodiazepine muscle relaxant: GYKI 52466

1989 • 144 citations

Impaired object recognition memory in rats following ischemia-induced damage to the hippocampus.

1993 • 143 citations

Neuroprotective Properties of the Novel Antiepileptic Lamotrigine in a Gerbil Model of Global Cerebral Ischemia

1995 • 132 citations

Spatial learning is affected by transient occlusion of common carotid arteries (2VO): Comparison of behavioural and histopathological changes after ‘2VO’ and ‘four-vessel-occlusion’ in rats

1990 • 132 citations

An unanesthetized-gerbil model of cerebral ischemia-induced behavioral changes

1985 • 109 citations

Relation of spatial learning of rats in the Morris water maze task to the number of viable CA1 neurons following four-vessel occlusion.

1994 • 106 citations

Post-Ischemic Resuscitation of the Brain: Selective Vulnerability Versus Global Resistance

1985 • 79 citations

Posttreatment with EPC-K1, an inhibitor of lipid peroxidation and of phospholipase A2 activity, reduces functional deficits after global ischemia in rats

1995 • 37 citations

Effect of the Non‐NMDA Receptor Antagonist GYKI 52466 on the Microdialysate and Tissue Concentrations of Amino Acids Following Transient Forebrain Ischaemia

1994 • 31 citations

S-emopamil ameliorates ischemic brain damage in rats: Histological and behavioural approaches

1990 • 29 citations

The depressant effect of GYKI 52466 on spinal reflex transmission in rats is mediated via non-NMDA and benzodiazepine receptors

1994 • 25 citations

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