Lung recruitment and lung volume maintenance: a strategy for improving oxygenation and preventing lung injury during both conventional mechanical ventilation and high-frequency oscillation

Effect of a Protective-Ventilation Strategy on Mortality in the Acute Respiratory Distress Syndrome

1998 • 3,553 citations

High Inflation Pressure Pulmonary Edema: Respective Effects of High Airway Pressure, High Tidal Volume, and Positive End-expiratory Pressure

1988 • 1,647 citations

Tidal ventilation at low airway pressures can augment lung injury.

1994 • 1,233 citations

Evaluation of a Ventilation Strategy to Prevent Barotrauma in Patients at High Risk for Acute Respiratory Distress Syndrome

1998 • 874 citations

Intuitive Biostatistics.

1997 • 799 citations

Tidal Volume Reduction for Prevention of Ventilator-induced Lung Injury in Acute Respiratory Distress Syndrome

1998 • 776 citations

Beneficial effects of the "open lung approach" with low distending pressures in acute respiratory distress syndrome. A prospective randomized study on mechanical ventilation.

1995 • 627 citations

In Vivo Lung Lavage as an Experimental Model of the Respiratory Distress Syndrome

1980 • 612 citations

Intermittent positive-pressure hyperventilation with high inflation pressures produces pulmonary microvascular injury in rats

1987 • 574 citations

Total Respiratory Pressure-Volume Curves in the Adult Respiratory Distress Syndrome

1984 • 463 citations

Permissive hypercapnia. How permissive should we be?

1994 • 427 citations

The Pressure–Volume Curve Is Greatly Modified by Recruitment

1998 • 409 citations

Lung Volume Maintenance Prevents Lung Injury during High Frequency Oscillatory Ventilation in Surfactant-deficient Rabbits

1988 • 402 citations

The Provo Multicenter Early High-frequency Oscillatory Ventilation Trial: Improved Pulmonary and Clinical Outcome in Respiratory Distress Syndrome

1996 • 376 citations

Lung myeloperoxidase as a measure of pulmonary leukostasis in rabbits

1985 • 369 citations

Sigh in Acute Respiratory Distress Syndrome

1999 • 366 citations

Comparison of conventional and high-frequency ventilation: oxygenation and lung pathology

1983 • 351 citations

A mouse model for investigating the molecular pathogenesis of adenovirus pneumonia.

1991 • 348 citations

Acute lung injury from mechanical ventilation at moderately high airway pressures

1990 • 336 citations

Adverse Effects of Large Tidal Volume and Low PEEP in Canine Acid Aspiration

1990 • 322 citations

High-frequency oscillatory ventilation for adult respiratory distress syndrome-A pilot study

1997 • 315 citations

Avalanches and power-law behaviour in lung inflation

1994 • 299 citations

Surface Tension as a Factor in Pulmonary Volume-Pressure Hysteresis

1957 • 263 citations

Severe Impairment in Lung Function Induced by High Peak Airway Pressure during Mechanical Ventilation

2015 • 234 citations

Oxygenation during High-Frequency Ventilation Compared with Conventional Mechanical Ventilation in Two Models of Lung Injury

1982 • 221 citations

Safety and efficacy of a sustained inflation for alveolar recruitment in adults with respiratory failure

1999 • 221 citations

Pressure-volume curves of air- and liquid-filled excised lungs-surface tension in situ.

1970 • 196 citations

Lung Surfactant and the Pathogenesis of Neonatal Bronchiolar Lesions Induced by Artificial Ventilation

1978 • 180 citations

Effects of positive end-expiratory pressure on hyaline membrane formation in a rabbit model of the neonatal respiratory distress syndrome

1988 • 169 citations

FACTORS INFLUENCING THE ARTERIAL OXYGEN TENSION DURING ANAESTHESIA WITH ARTIFICIAL VENTILATION

1965 • 164 citations

The Mechanism of Lung Volume Change during Mechanical Ventilation

1999 • 144 citations

Causes of error of respiratory pressure-volume curves in paralyzed subjects

1988 • 99 citations

Effect of changes in tidal ventilation on physiologic shunting

1964 • 89 citations

Volume recruitment maneuvers are less deleterious than persistent low lung volumes in the atelectasisprone rabbit lung during high-frequency oscillation

1993 • 86 citations

Sustained inflations improve respiratory compliance during high-frequency oscillatory ventilation but not during large tidal volume positive-pressure ventilation in rabbits

1994 • 78 citations

Respiratory mechanics in patients ventilated for critical lung disease

1996 • 72 citations

Relationship of lung recoil to lung volume and maximum expiratory flow in normal children

1977 • 68 citations

Improved determination of static compliance by automated single volume steps in ventilated patients

1991 • 68 citations

Permissive hypercapnia in ARDS and its effect on tissue oxygenation

1995 • 62 citations

Relationship between Pa_O2 and Lung Volume during High Frequency Oscillatory Ventilation

1992 • 52 citations

High-frequency oscillation compared with standard ventilation in pulmonary injury model

1982 • 51 citations

Lung volume recruitment during high-frequency oscillation in atelectasis-prone rabbits

1988 • 50 citations

Sustained inflation during HFOV improves pulmonary mechanics and oxygenation

1988 • 45 citations

Evidence of sequential opening and closing of lung units during inflation-deflation of excised rat lungs

1985 • 44 citations

Safety and efficacy of a sustained inflation for alveolar recruitment in adults with respiratory failure

1999 • 27 citations

Sigh in acute respiratory distress syndrome

1999 • 27 citations

High-frequency oscillatory ventilation is not superior to conventional mechanical ventilation in surfactant-treated rabbits with lung injury

1999 • 20 citations

HIGH-INFLATION PRESSURE AND POSITIVE END-EXPIRATORY

1996 • 9 citations

Volume recruitment and oxygenation in pulmonary edema: A comparison between HFOV and CMV

1998 • 9 citations