Flunitrazepam and nordiazepam slowly released from silastic capsules induce physical dependence in rat

Pharmacological characterization of benzodiazepine receptors in the brain

1978 • 285 citations

Precipitated Withdrawal by a Benzodiazepine Receptor Antagonist (Ro 15-1788) After 7 Days of Diazepam

1982 • 154 citations

Determinants of benzodiazepine brain uptake: lipophilicity versus binding affinity

1987 • 121 citations

Continuous release of diazepam: Electrophysiological, biochemical and behavioral consequences

1985 • 105 citations

The pharmacokinetics of diazepam and desmethyldiazepam in rat brain and plasma

1986 • 103 citations

Use of the specific benzodiazepine antagonist, Ro 15-1788, in studies of physiological dependence on benzodiazepines

1982 • 96 citations

Diazepam and pentobarbital dependence in the rat

1982 • 68 citations

The effect of a benzodiazepine antagonist, R015-1788, in diazepam dependent rats

1982 • 66 citations

Ro 15-1788-induced seizures in rats continually exposed to diazepam for prolonged periods

1988 • 37 citations

Continuous slow release of low levels of diazepam produces tolerance to its depressant and anxiolytic effects on the startle reflex

1988 • 34 citations

Precipitated abstinence in the diazepam-dependent rat

1993 • 26 citations

Physical dependence on diazepam in the dog: precipitation of different abstinence syndromes by the benzodiazepine receptor antagonists Ro 15–1788 and ZK 93426

1989 • 21 citations

Physical dependence on diazepam: Precipitation of abstinence syndromes by peripheral and central benzodiazepine receptor antagonists

1992 • 21 citations

Effect of the chronic dose of diazepam on the intensity and characteristics of the precipitated abstinence syndrome in the dog.

1993 • 14 citations

A comparison of the physical dependence inducing properties of flunitrazepam and diazepam

1991 • 13 citations

Pharmacokinetics of flunitrazepam in rats studied by a radioreceptor assay

1985 • 13 citations

Rapid tolerance to the depressive effects of diazepam on guinea pig motor control using divided doses

1994 • 8 citations

Physical dependence of benzodiazepines in the rat and dog.

1986 • 6 citations