Heparin-hepatocyte growth factor complex with low plasma clearance and retained hepatocyte proliferating activity

Molecular cloning and expression of human hepatocyte growth factor

1989 • 2,191 citations

Proteoglycans as modulators of growth factor activities

1991 • 1,338 citations

Physiological Role of Silent Receptors of Atrial Natriuretic Factor

1987 • 930 citations

Heparin protects basic and acidic FGF from inactivation

1986 • 856 citations

Purification and partial characterization of hepatocyte growth factor from plasma of a patient with fulminant hepatic failure.

1988 • 657 citations

Purification and characterization of a growth factor from rat platelets for mature parenchymal hepatocytes in primary cultures.

1986 • 588 citations

Purification and subunit structure of hepatocyte growth factor from rat platelets

1987 • 557 citations

Purification and biological characterization of human hepatopoietin A, a polypeptide growth factor for hepatocytes.

1989 • 455 citations

Deduced primary structure of rat hepatocyte growth factor and expression of the mRNA in rat tissues.

1990 • 333 citations

Direct evidence that hepatocyte growth factor is a hepatotrophic factor for liver regeneration and has a potent antihepatitis effectin vivo

1992 • 331 citations

Expression of hepatocyte growth factor gene in endothelial and kupffer cells of damaged rat livers, as revealed by insitu hydridization

1990 • 299 citations

Receptor-mediated endocytosis of epidermal growth factor by hepatocytes in the perfused rat liver: ligand and receptor dynamics.

1984 • 265 citations

Marked increase of HGF mRNA in non-parenchymal liver cells of rats treated with hepatotoxins

1989 • 248 citations

Lung may have an endocrine function producing hepatocyte growth factor in response to injury of distal organs

1992 • 212 citations

Heparin protects heparin-binding growth factor-I from proteolytic inactivation in vitro

1988 • 149 citations

Identification and characterization of "injurin," an inducer of expression of the gene for hepatocyte growth factor.

1992 • 148 citations

Identification and change in the receptor for hepatocyte growth factor in rat liver after partial hepatectomy or induced hepatitis

1991 • 123 citations

The gene of hepatocyte growth factor is expressed in fat-storing cells of rat liver and is downregulated during cell growth and by transforming growth factor-β

1992 • 109 citations

Sequestration of a hepatocyte growth factor in extracellular matrix in normal adult rat liver

1991 • 105 citations

Purification and characterization of hepatocyte growth factor from injured liver of carbon tetrachloride-treated rats.

1991 • 102 citations

Screening for candidate hepatic growth factors by selective portal infusion after canine Eck’s fistula

1991 • 100 citations

Transport of epidermal growth factor by rat liver: evidence for a nonlysosomal pathway.

1984 • 96 citations

Contractile arrest accelerates myosin heavy chain degradation in neonatal rat heart cells

1992 • 93 citations

Receptor-mediated transport of peptide hormones and its importance in the overall hormone disposition in the body.

1989 • 79 citations

Tissue Distribution of Hepatocyte Growth Factor Receptor and Its Exclusive Down-Regulation in a Regenerating Organ after Injury1

1992 • 72 citations

Identification and partial characterization of receptor binding sites for HGF on rat hepatocytes

1990 • 69 citations

Cell Density-Dependent Regulation of Albumin Synthesis and DNA Synthesis in Rat Hepatocytes by Hepatocyte Growth Factor

1992 • 66 citations

Hepatocyte growth factor is a paracrine factor for renal epithelial cells: Stimulation of DNA synthesis and Na,K-ATPase activity

1992 • 57 citations

Decrease in the hepatic clearance of hepatocyte growth factor in carbon tetrachloride–intoxicated rats

1993 • 54 citations

Dynamic determination of kinetic parameters for the interaction between polypeptide hormones and cell-surface receptors in the perfused rat liver by the multiple-indicator dilution method.

1988 • 47 citations

Kinetic analysis of the downregulation of epidermal growth factor receptors in rats in vivo

1990 • 36 citations

Replacement of molecular species of phosphatidylcholine: influence on erythrocyte Na transport

1990 • 33 citations

Kinetic analysis of receptor-mediated endocytosis of epidermal growth factor by isolated rat hepatocytes

1991 • 33 citations

Existence of two pathways for the endocytosis of epidermal growth factor by rat liver: phenylarsine oxide-sensitive and -insensitive pathways.

1992 • 31 citations

Effect on the canine Eck fistula liver of intraportal TGF-β alone or with hepatic growth factors

1992 • 26 citations

Receptor-mediated disposition of polypeptides: Kinetic analysis of the transport of epidermal growth factor as a model peptide using in vitro isolated perfused organs and in vivo system

1990 • 17 citations

Disposition of tritium-labelled heparin in rats.

1982 • 16 citations

Internalization of EGF in perfused rat liver is independent of the degree of receptor occupancy

1990 • 15 citations

Deleted Work

1955 • 0 citations