BRAF mutation, CpG island methylator phenotype and microsatellite instability occur more frequently and concordantly in mucinous than non‐mucinous colorectal cancer
Data up to Jan 2025
Total Citations Per Year
Abstract
References (42)
Mutations of the BRAF gene in human cancer
2002 • 10,249 citations
Lessons from Hereditary Colorectal Cancer
1996 • 4,900 citations
CpG island methylator phenotype in colorectal cancer
1999 • 2,476 citations
Mutation in the DNA mismatch repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer
1994 • 2,071 citations
Genetic instability in colorectal cancers
1997 • 1,989 citations
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
1998 • 1,852 citations
Somatic Frameshift Mutations in the BAX Gene in Colon Cancers of the Microsatellite Mutator Phenotype
1997 • 1,329 citations
RAF/RAS oncogenes and mismatch-repair status
2002 • 1,205 citations
CpG island methylator phenotype in cancer
2004 • 1,052 citations
BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum
2004 • 716 citations
The Raf/MEK/ERK pathway: new concepts of activation
2001 • 716 citations
Microsatellite instability is associated with tumors that characterize the hereditary non-polyposis colorectal carcinoma syndrome.
1993 • 596 citations
Hypermethylation-associated inactivation of p14(ARF) is independent of p16(INK4a) methylation and p53 mutational status.
2000 • 470 citations
Distinct genetic profiles in colorectal tumors with or without the CpG island methylator phenotype
2000 • 462 citations
Similarity of the phenotypic patterns associated with BRAF and KRAS mutations in colorectal neoplasia.
2002 • 408 citations
BRAF Mutation Is Frequently Present in Sporadic Colorectal Cancer with Methylated hMLH1, But Not in Hereditary Nonpolyposis Colorectal Cancer
2004 • 404 citations
CpG island methylation in sporadic colorectal cancers and its relationship to microsatellite instability
2002 • 371 citations
Epigenetic changes in colorectal cancer
2003 • 335 citations
Association between CpG island methylation and microsatellite instability in colorectal cancer.
1997 • 295 citations
Characterization of sporadic colon cancer by patterns of genomic instability.
2003 • 259 citations
Characterisation of colorectal cancers showing hypermethylation at multiple CpG islands
2002 • 257 citations
Colorectal Cancer With Mutation in BRAF, KRAS, and Wild-Type With Respect to Both Oncogenes Showing Different Patterns of DNA Methylation
2004 • 218 citations
CpG Island Methylation in Colorectal Adenomas
2001 • 207 citations
Genomic instability and cancer
1991 • 185 citations
Mucinous carcinoma—Just another colon cancer?
1993 • 176 citations
Clinicopathological characteristics of mucinous carcinoma of the colon and rectum
2000 • 171 citations
Primary Mucinous Adenocarcinomas and Signet-Ring Cell Carcinomas of Colon and Rectum
1994 • 153 citations
Mucinous carcinoma of the colon: correlation of loss of mismatch repair enzymes with clinicopathologic features and survival
2004 • 147 citations
Aberrant CpG island hypermethylation of multiple genes in colorectal neoplasia
2004 • 146 citations
Mutations of BRAF are associated with extensive hMLH1 promoter methylation in sporadic colorectal carcinomas
2003 • 129 citations
Epigenetic Inactivation of ID4 in Colorectal Carcinomas Correlates with Poor Differentiation and Unfavorable Prognosis
2004 • 106 citations
CpG island promoter hypermethylation of a novel Ras-effector gene RASSF2A is an early event in colon carcinogenesis and correlates inversely with K-ras mutations
2005 • 106 citations
p14 methylation in human colon cancer is associated with microsatellite instability and wild-type p53
2003 • 97 citations
Methylation of hMLH1 promoter correlates with the gene silencing with a region-specific manner in colorectal cancer
2002 • 97 citations
Mutant ras epitopes as targets for cancer vaccines.
1996 • 87 citations
Microsatellite instability in sporadic mucinous colorectal carcinomas: relationship to clinico-pathological variables
1997 • 87 citations
Clinicopathological and genetic characteristics of mucinous carcinomas in the colorectum.
1999 • 87 citations
Mucinous carcinomas of the colorectum have distinct molecular genetic characteristics
2005 • 85 citations
Is mucinous carcinoma of the colorectum a distinct genetic entity?
1995 • 84 citations
Phenotype of Microsatellite-Stable Colorectal Carcinomas With CpG Island Methylation
2005 • 62 citations
Methylation of the hMLH1, p16, and MDR1 genes in colorectal carcinoma: associations with clinicopathological features
2001 • 46 citations
Immunohistochemical and mutational analyses of beta-catenin, Ki-ras, and p53 in two subtypes of colorectal mucinous carcinoma.
2003 • 18 citations
Cited By (0)
No citing papers found in database