Dynamin GTPase, a force‐generating molecular switch

The GTPase superfamily: conserved structure and molecular mechanism

1991 • 3,365 citations

Induction of mutant dynamin specifically blocks endocytic coated vesicle formation.

1994 • 1,206 citations

Dynamin self-assembles into rings suggesting a mechanism for coated vesicle budding

1995 • 816 citations

Tubular membrane invaginations coated by dynamin rings are induced by GTP-γS in nerve terminals

1995 • 760 citations

Dynamin-like protein encoded by the Drosophila shibire gene associated with vesicular traffic

1991 • 757 citations

Mutations in human dynamin block an intermediate stage in coated vesicle formation

1993 • 702 citations

Predicting coiled coils by use of pairwise residue correlations.

1995 • 626 citations

Multiple forms of dynamin are encoded by shibire, a Drosophila gene involved in endocytosis

1991 • 543 citations

Effects of mutant rat dynamin on endocytosis

1993 • 453 citations

Disappearance and reformation of synaptic vesicle membrane upon transmitter release observed under reversible blockage of membrane retrieval

1989 • 442 citations

Identification of dynamin, a novel mechanochemical enzyme that mediates interactions between microtubules

1989 • 436 citations

A role of amphiphysin in synaptic vesicle endocytosis suggested by its binding to dynamin in nerve terminals.

1996 • 408 citations

Clathrin-independent pinocytosis is induced in cells overexpressing a temperature-sensitive mutant of dynamin.

1995 • 400 citations

Temperature-sensitive mutations in Drosophila melanogaster

1973 • 356 citations

Molecular cloning of the microtubule-associated mechanochemical enzyme dynamin reveals homology with a new family of GTP-binding proteins

1990 • 352 citations

Possible temperature‐dependent blockage of synaptic vesicle recycling induced by a single gene mutation in drosophila

1983 • 303 citations

The pleckstrin homology domain: An intriguing multifunctional protein module

1996 • 285 citations

Crystal structure at 2.2 Å resolution of the pleckstrin homology domain from human dynamin

1994 • 268 citations

Dynamin Self-assembly Stimulates Its GTPase Activity

1996 • 262 citations

Identification of the Binding Site for Acidic Phospholipids on the PH Domain of Dynamin: Implications for Stimulation of GTPase Activity

1996 • 250 citations

Dynamin is a GTPase stimulated to high levels of activity by microtubules

1992 • 211 citations

The VPS1 protein, a homolog of dynamin required for vacuolar protein sorting in Saccharomyces cerevisiae, is a GTPase with two functionally separable domains.

1992 • 202 citations

SH3 Domains: Minding your p's and q's

1995 • 197 citations

Reversible alteration in the neuromuscular junctions of Drosophila melanogaster bearing a temperature-sensitive mutation, shibire.

1979 • 193 citations

Multiple GTP-binding proteins participate in clathrin-coated vesicle-mediated endocytosis.

1993 • 188 citations

Identification of dynamin 2, an isoform ubiquitously expressed in rat tissues.

1994 • 185 citations

The Appendage Domain of α-Adaptin Is a High Affinity Binding Site for Dynamin

1995 • 184 citations

Differential expression and regulation of multiple dynamins.

1994 • 172 citations

Phragmoplastin, a dynamin-like protein associated with cell plate formation in plants.

1996 • 170 citations

Activation of dynamin GTPase by acidic phospholipids and endogenous rat brain vesicles

1993 • 164 citations

A Binding Site for SH3 Domains Targets Dynamin to Coated Pits

1996 • 161 citations

The function of dynamin in endocytosis

1995 • 159 citations

Microtubules and Src homology 3 domains stimulate the dynamin GTPase via its C-terminal domain.

1993 • 137 citations

DNM1, a dynamin-related gene, participates in endosomal trafficking in yeast.

1995 • 126 citations

Phosphorylation of dynamin I and synaptic-vesicle recycling

1994 • 117 citations

Association of a dynamin-like protein with the Golgi apparatus in mammalian cells.

1996 • 115 citations

Interaction of dynamin with microtubules: its structure and GTPase activity investigated by using highly purified dynamin.

1992 • 110 citations

Biochemical and immunochemical analysis of rat brain dynamin interaction with microtubules and organelles in vivo and in vitro.

1990 • 110 citations

A novel member of the dynamin family of GTP-binding proteins is expressed specifically in the testis

1993 • 104 citations

Three-dimensional solution structure of the pleckstrin homology domain from dynamin

1994 • 92 citations

Dynamin GTPase is stimulated by crosslinking through the C-terminal proline-rich domain.

1995 • 85 citations

Activation of dynamin GTPase is a result of positive cooperativity.

1994 • 85 citations

Dynamin and Endocytosis*

1995 • 76 citations

Membranous intermediates in endocytosis are labile, as shown in a temperature-sensitive mutant.

1989 • 74 citations

Dynamin and receptor‐mediated endocytosis

1996 • 74 citations

Interferon-induced MxA Protein.

1995 • 71 citations

Unexpected Structural Requirements for GTPase Activity of the Interferon-induced MxA Protein

1995 • 70 citations

Genetic Studies on Dynamin Function inDrosophila

1993 • 57 citations

The regulation of endocytosis: identifying dynamin's binding partners

1995 • 54 citations

Synchronized endocytosis studied in the oocyte of a temperature-sensitive mutant of Drosophila melanogaster

1990 • 49 citations

Role of Dynamin in Clathrin-eoated Vesicle Formation

1995 • 47 citations

Transformational process of the endosomal compartment in nephrocytes of Drosophila melanogaster

1990 • 44 citations

Coated-vesicle formation in vitro: Conflicting results using different assays

1993 • 42 citations

Allelic Interactions at theShibireLocus ofDrosophila: Effects on Behavior

1990 • 40 citations

Calcium Binds Dynamin I and Inhibits Its GTPase Activity

1996 • 39 citations

Dynamin and endocytosis

1995 • 32 citations

Two Isoforms ofDrosophilaDynamin in Wild-Type andShibire^tsNeural Tissue: Different Subcellular Localization and Association Mechanisms

1995 • 11 citations