Atypical antipsychotics: are some more atypical than others?

Clozapine for the Treatment-Resistant Schizophrenic

1988 • 4,030 citations

Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values.

1989 • 1,313 citations

Deficit and nondeficit forms of schizophrenia: the concept

1988 • 1,307 citations

Risperidone in the treatment of schizophrenia

1994 • 1,205 citations

Olanzapine versus haloperidol in the treatment of schizophrenia and schizoaffective and schizophreniform disorders: results of an international collaborative trial

1997 • 906 citations

A Canadian Multicenter Placebo-Controlled Study of Fixed Doses of Risperidone and Haloperidol in the Treatment of Chronic Schizophrenic Patients

1993 • 884 citations

Serotonin-dopamine interaction and its relevance to schizophrenia

1996 • 822 citations

The schedule for the deficit syndrome: An instrument for research in schizophrenia

1989 • 806 citations

Olanzapine versus Placebo and Haloperidol

1996 • 788 citations

Double-Blind Comparison of Olanzapine Versus Risperidone in the Treatment of Schizophrenia and Other Psychotic Disorders

1997 • 722 citations

Clinical and Theoretical Implications of 5-HT₂ and D₂ Receptor Occupancy of Clozapine, Risperidone, and Olanzapine in Schizophrenia

1999 • 706 citations

Significance of Neuroleptic Dose and Plasma Level in the Pharmacological Treatment of Psychoses

1988 • 554 citations

Childhood-Onset Schizophrenia

1996 • 395 citations

Optimal Dose of Neuroleptic in Acute Schizophrenia

1991 • 384 citations

Clinical and Biologic Response to Clozapine in Patients With Schizophrenia

1992 • 356 citations

Mechanisms of action of atypical antipsychotic drugs: a critical analysis

1996 • 315 citations

Risperidone versus haloperidol in the treatment of chronic schizophrenic inpatients: a multicentre double‐blind comparative study

1992 • 302 citations

Blind, controlled, long-term study of the comparative incidence of treatment-emergent tardive dyskinesia with olanzapine or haloperidol

1997 • 287 citations

Tolerability and therapeutic effect of clozapine

1985 • 277 citations

Positive and Negative Symptom Response to Clozapine in Schizophrenic Patients With and Without the Deficit Syndrome

1998 • 258 citations

High levels of dopamine D2 receptor occupancy with low-dose haloperidol treatment: a PET study

1996 • 257 citations

Dimensions of Outcome with Clozapine

1992 • 256 citations

A comparison of quetiapine and chlorpromazine in the treatment of schizophrenia

1997 • 253 citations

Olanzapine Compared With Chlorpromazine in Treatment-Resistant Schizophrenia

1998 • 239 citations

Risperidone: clinical safety and efficacy in schizophrenia.

1992 • 208 citations

Clozapine and Risperidone in Chronic Schizophrenia: Effects on Symptoms, Parkinsonian Side Effects, and Neuroendocrine Response

1999 • 198 citations

An Exploratory Haloperidol-Controlled Dose-Finding Study of Ziprasidone in Hospitalized Patients With Schizophrenia or Schizoaffective Disorder

1998 • 188 citations

Risperidone versus perphenazine in the treatment of chronic schizophrenic patients with acute exacerbations

1993 • 177 citations

The history of clozapine

1989 • 170 citations

The New Atypical Antipsychotics

1994 • 168 citations

Atypical antipsychotic drugs as a first-line treatment of schizophrenia: a rationale and hypothesis.

1996 • 139 citations

Antipsychotic drugs: is more worse? a meta-analysis of the published randomized control trials

1994 • 136 citations

Randomized, Double-Blind, Controlled Trial of Risperidone Versus Clozapine in Patients With Chronic Schizophrenia

1995 • 122 citations

Olanzapine Versus Placebo and Haloperidol: Quality of Life and Efficacy Results of the North American Double-Blind Trial

1998 • 120 citations

Antipsychotic and Anxiolytic Properties of Risperidone, Haloperidol, and Methotrimeprazine in Schizophrenic Patients

1996 • 120 citations

Clozapine's effect on negative symptoms in treatment-refractory schizophrenics

1994 • 112 citations

New antipsychotics: the present status

1995 • 102 citations

A 5-year prospective longitudinal study of tardive dyskinesia: factors predicting appearance of new cases.

1988 • 101 citations

Risperidone versus zuclopenthixol in the treatment of acute schizophrenic episodes: a double‐blind parallel‐group trial

1995 • 99 citations

A new framework for investigating antipsychotic action in humans: lessons from PET imaging

1998 • 80 citations

Different side effect profiles of risperidone and clozapine in 20 outpatients with schizophrenia or schizoaffective disorder: a pilot study

1996 • 74 citations

Clozapine versus typical antipsychotics a retro- and prospective study of extrapyramidal side effects

1996 • 71 citations

Plasma Haloperidol Levels and Clinical Effects in Schizophrenia and Schizoaffective Disorder

1995 • 55 citations

Motor and mental side effects of clozapine.

1994 • 55 citations

Effects of switching inpatients with treatment-resistant schizophrenia from clozapine to risperidone

1996 • 54 citations

Clozapine efficacy in schizophrenic nonresponders.

1988 • 44 citations

The new antipsychotics, and their potential for early intervention in schizophrenia

1997 • 42 citations

Treatment-resistant schizophrenia: clinical experience with new antipsychotics

1996 • 40 citations

Efficacy of Risperidone in Reducing Positive and Negative Symptoms in Medication-Refractory Schizophrenia

1996 • 40 citations

What Makes an Antipsychotic ‘Atypical’?

1997 • 37 citations

The negative component in schizophrenia

1995 • 29 citations

A pilot, open study on the treatment of refractory schizophrenia with risperidone and clozapine

1995 • 25 citations

The Atypical Antipsychotic Sertindole

1997 • 15 citations

New findings on tardive dyskinesia in a community sample

1993 • 12 citations

Medical Complications and Selectivity of Therapeutic Response to Atypical Antipsychotic Drugs

1998 • 12 citations

LOW FREQUENCY OF TARDIVE DYSKINESIA IN ELDERLY PATIENTS WITH DEMENTIA EXPOSED TO RISPERIDONE FOR UP TO ONE YEAR

1999 • 9 citations