Death-Defying Yeast Identify Novel Apoptosis Genes

Apaf-1, a Human Protein Homologous to C. elegans CED-4, Participates in Cytochrome c–Dependent Activation of Caspase-3

1997 • 3,130 citations

Caspases: Intracellular Signaling by Proteolysis

1997 • 2,114 citations

The proto-oncogene Bcl-2 and its role in regulating apoptosis

1997 • 1,768 citations

The molecular biology of apoptosis.

1996 • 963 citations

BAX-induced cell death may not require interleukin 1β-converting enzyme-like proteases

1996 • 911 citations

A Yeast Mutant Showing Diagnostic Markers of Early and Late Apoptosis

1997 • 788 citations

Cytochrome c: Can't Live with It—Can't Live without It

1997 • 768 citations

Bax Inhibitor-1, a Mammalian Apoptosis Suppressor Identified by Functional Screening in Yeast

1998 • 514 citations

Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2

1997 • 489 citations

The molecular biology of apoptoseis.

1996 • 390 citations

Release of cytochrome c and decrease of cytochrome c oxidase in Bax‐expressing yeast cells, and prevention of these effects by coexpression of Bcl‐x_L

1997 • 288 citations

Structure-Function Comparisons of the Proapoptotic Protein Bax in Yeast and Mammalian Cells

1996 • 280 citations

The Mitochondrial F0F1-ATPase Proton Pump Is Required for Function of the Proapoptotic Protein Bax in Yeast and Mammalian Cells

1998 • 273 citations

Developing Caenorhabditis elegans neurons may contain both cell-death protective and killer activities.

1996 • 236 citations

Human Bcl-2 Reverses Survival Defects in Yeast Lacking Superoxide Dismutase and Delays Death of Wild-Type Yeast

1997 • 203 citations

The Genetics of Programmed Cell Death in the Nematode Caenorhabditis elegans

1994 • 195 citations

Human Bak Induces Cell Death in Schizosaccharomyces pombe with Morphological Changes Similar to Those with Apoptosis in Mammalian Cells

1997 • 125 citations