Monoclonal antibodies in the treatment of colorectal cancer
Data up to Jan 2025
Total Citations Per Year
Abstract
References (54)
Angiogenesis in cancer and other diseases
2000 • 8,734 citations
Cancer: Principles and Practice of Oncology.
1991 • 8,402 citations
Cancer Statistics, 2003
2003 • 3,302 citations
Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: half of patients respond to a four-dose treatment program.
1998 • 2,777 citations
Epidermal growth factor-related peptides and their receptors in human malignancies
1995 • 2,689 citations
A Randomized Controlled Trial of Fluorouracil Plus Leucovorin, Irinotecan, and Oxaliplatin Combinations in Patients With Previously Untreated Metastatic Colorectal Cancer
2003 • 2,212 citations
Cancer burden in the year 2000. The global picture
2001 • 2,206 citations
EGFR and cancer prognosis
2001 • 2,068 citations
Phase II, Randomized Trial Comparing Bevacizumab Plus Fluorouracil (FU)/Leucovorin (LV) With FU/LV Alone in Patients With Metastatic Colorectal Cancer
2002 • 1,699 citations
Molecular and Biological Properties of the Vascular Endothelial Growth Factor Family of Proteins
1992 • 1,612 citations
The EGF receptor family as targets for cancer therapy
2000 • 1,339 citations
Cancer: Principles and Practice of Oncology.
1986 • 1,140 citations
A novel approach in the treatment of cancer: targeting the epidermal growth factor receptor.
2001 • 988 citations
Phase I Safety and Pharmacokinetic Study of Recombinant Human Anti-Vascular Endothelial Growth Factor in Patients With Advanced Cancer
2001 • 923 citations
Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: angiogenic implications for signal transduction therapy of solid tumors.
1997 • 841 citations
The Epidermal Growth Factor Receptor and Its Inhibition in Cancer Therapy
1999 • 840 citations
Phase I Studies of Anti–Epidermal Growth Factor Receptor Chimeric Antibody C225 Alone and in Combination With Cisplatin
2000 • 748 citations
IDEC-C2B8: results of a phase I multiple-dose trial in patients with relapsed non-Hodgkin's lymphoma.
1997 • 638 citations
The biology of the 17–1A antigen (Ep-CAM)
1999 • 541 citations
Monoclonal antibody therapy for resected Dukes' C colorectal cancer: seven-year outcome of a multicenter randomized trial.
1998 • 530 citations
Development of ABX-EGF, a fully human anti-EGF receptor monoclonal antibody, for cancer therapy
2001 • 452 citations
The role of vascular endothelial growth factor in pathological angiogenesis
1995 • 419 citations
The prognostic significance of proliferating cell nuclear antigen, epidermal growth factor receptor, andmdr gene expression in colorectal cancer
1993 • 415 citations
Developing Inhibitors of the Epidermal Growth Factor Receptor for Cancer Treatment
2003 • 385 citations
Colorectal cancer
1999 • 312 citations
Tumor localization in patients by radiolabeled monoclonal antibodies against colon carcinoma.
1983 • 286 citations
[Cancer of the colon].
1951 • 277 citations
Phase I Study of the Humanized Antiepidermal Growth Factor Receptor Monoclonal Antibody EMD72000 in Patients With Advanced Solid Tumors That Express the Epidermal Growth Factor Receptor
2003 • 264 citations
Consequences of angiogenesis for tumor progression, metastasis and cancer therapy
1995 • 243 citations
The fibroblast growth factor family.
1990 • 219 citations
Edrecolomab alone or in combination with fluorouracil and folinic acid in the adjuvant treatment of stage III colon cancer: a randomised study
2002 • 214 citations
Tumor Angiogenesis as a Prognostic Predictor in Colorectal Carcinoma with Special Reference to Mode of Metastasis and Recurrence
1998 • 159 citations
Prospective study of intratumoral microvessel density, p53 expression and survival in colorectal cancer
1998 • 149 citations
Phase I Trial of Multiple Large Doses of Murine Monoclonal Antibody CO17-1A. II. Pharmacokinetics and Immune Response1
1988 • 122 citations
Inhibition of vascular endothelial growth factor in the treatment of colorectal cancer
2003 • 107 citations
Effect of monoclonal antibody 17‐1A and gm‐CSF in patients with advanced colorectal carcinoma—long‐lasting, complete remissions can be induced
1993 • 101 citations
Changes of angiogenesis and tumor cell apoptosis during colorectal carcinogenesis.
1999 • 92 citations
The impact of antigen density and antibody affinity on antibody-dependent cellular cytotoxicity: relevance for immunotherapy of carcinomas
1998 • 90 citations
Monoclonal antibodies as therapeutics in oncology
2002 • 84 citations
Clinical experience with edrecolomab: a monoclonal antibody therapy for colorectal carcinoma
2001 • 82 citations
Granulocyte-monocyte-colony-stimulating factor augments the cytotoxic capacity of lymphocytes and monocytes in antibody-dependent cellular cytotoxicity
1989 • 70 citations
Immunohistochemical monitoring of metastatic colorectal carcinoma in patients treated with monoclonal antibodies (MAb 17-1A)
1988 • 61 citations
Pharmacokinetics of the mouse monoclonal antibody 17-1A in cancer patients receiving various treatment schedules.
1990 • 57 citations
CO 17-1A and related monoclonal antibodies: their production and characterization.
1986 • 55 citations
Therapeutics targeting signal transduction for patients with colorectal carcinoma
2002 • 53 citations
Magic Bullets Fly Again
2001 • 47 citations
A phase II trial of murine monoclonal antibody 17-1A and interferon-γ: Clinical and immunological data
1990 • 46 citations
Update of clinical trials with edrecolomab: A monoclonal antibody therapy for colorectal cancer
2001 • 42 citations
Tumor-Associated Antigen Expression of Primary and Metastatic Colon Carcinomas Detected by Monoclonal Antibody 17-1A
1987 • 37 citations
Steigert Körperliche Anstrengung die Disposition zu Epidemischer Kinderlähme
1938 • 23 citations
Antibodies in the therapy of colon cancer.
1999 • 22 citations
DIFFERENT DOSE REGIMENS OF THE MOUSE MONOCLONAL-ANTIBODY 17-1A FOR THERAPY OF PATIENTS WITH METASTATIC COLORECTAL-CARCINOMA
1995 • 15 citations
In vivo activity of humanized monoclonal anti-EGFR antibody EMD72000 in combination with gemcitabine on growth of primary pancreatic tumors and metastases in an orthotopic nude mouse model
2003 • 11 citations
Chemotherapy for colorectal cancer
2002 • 7 citations