Back to search

Monoclonal antibodies in the treatment of colorectal cancer

Data up to Jan 2025

Published2004
Citations73
References54

Total Citations Per Year

Abstract

References (54)

Angiogenesis in cancer and other diseases

2000 • 8,734 citations

Cancer: Principles and Practice of Oncology.

1991 • 8,402 citations

Cancer Statistics, 2003

2003 • 3,302 citations

Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: half of patients respond to a four-dose treatment program.

1998 • 2,777 citations

Epidermal growth factor-related peptides and their receptors in human malignancies

1995 • 2,689 citations

A Randomized Controlled Trial of Fluorouracil Plus Leucovorin, Irinotecan, and Oxaliplatin Combinations in Patients With Previously Untreated Metastatic Colorectal Cancer

2003 • 2,212 citations

Cancer burden in the year 2000. The global picture

2001 • 2,206 citations

EGFR and cancer prognosis

2001 • 2,068 citations

Phase II, Randomized Trial Comparing Bevacizumab Plus Fluorouracil (FU)/Leucovorin (LV) With FU/LV Alone in Patients With Metastatic Colorectal Cancer

2002 • 1,699 citations

Molecular and Biological Properties of the Vascular Endothelial Growth Factor Family of Proteins

1992 • 1,612 citations

The EGF receptor family as targets for cancer therapy

2000 • 1,339 citations

Cancer: Principles and Practice of Oncology.

1986 • 1,140 citations

A novel approach in the treatment of cancer: targeting the epidermal growth factor receptor.

2001 • 988 citations

Phase I Safety and Pharmacokinetic Study of Recombinant Human Anti-Vascular Endothelial Growth Factor in Patients With Advanced Cancer

2001 • 923 citations

Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: angiogenic implications for signal transduction therapy of solid tumors.

1997 • 841 citations

The Epidermal Growth Factor Receptor and Its Inhibition in Cancer Therapy

1999 • 840 citations

Phase I Studies of Anti–Epidermal Growth Factor Receptor Chimeric Antibody C225 Alone and in Combination With Cisplatin

2000 • 748 citations

IDEC-C2B8: results of a phase I multiple-dose trial in patients with relapsed non-Hodgkin's lymphoma.

1997 • 638 citations

The biology of the 17–1A antigen (Ep-CAM)

1999 • 541 citations

Monoclonal antibody therapy for resected Dukes' C colorectal cancer: seven-year outcome of a multicenter randomized trial.

1998 • 530 citations

Development of ABX-EGF, a fully human anti-EGF receptor monoclonal antibody, for cancer therapy

2001 • 452 citations

The role of vascular endothelial growth factor in pathological angiogenesis

1995 • 419 citations

The prognostic significance of proliferating cell nuclear antigen, epidermal growth factor receptor, andmdr gene expression in colorectal cancer

1993 • 415 citations

Developing Inhibitors of the Epidermal Growth Factor Receptor for Cancer Treatment

2003 • 385 citations

Colorectal cancer

1999 • 312 citations

Tumor localization in patients by radiolabeled monoclonal antibodies against colon carcinoma.

1983 • 286 citations

[Cancer of the colon].

1951 • 277 citations

Phase I Study of the Humanized Antiepidermal Growth Factor Receptor Monoclonal Antibody EMD72000 in Patients With Advanced Solid Tumors That Express the Epidermal Growth Factor Receptor

2003 • 264 citations

Consequences of angiogenesis for tumor progression, metastasis and cancer therapy

1995 • 243 citations

The fibroblast growth factor family.

1990 • 219 citations

Edrecolomab alone or in combination with fluorouracil and folinic acid in the adjuvant treatment of stage III colon cancer: a randomised study

2002 • 214 citations

Tumor Angiogenesis as a Prognostic Predictor in Colorectal Carcinoma with Special Reference to Mode of Metastasis and Recurrence

1998 • 159 citations

Prospective study of intratumoral microvessel density, p53 expression and survival in colorectal cancer

1998 • 149 citations

Phase I Trial of Multiple Large Doses of Murine Monoclonal Antibody CO17-1A. II. Pharmacokinetics and Immune Response1

1988 • 122 citations

Inhibition of vascular endothelial growth factor in the treatment of colorectal cancer

2003 • 107 citations

Effect of monoclonal antibody 17‐1A and gm‐CSF in patients with advanced colorectal carcinoma—long‐lasting, complete remissions can be induced

1993 • 101 citations

Changes of angiogenesis and tumor cell apoptosis during colorectal carcinogenesis.

1999 • 92 citations

The impact of antigen density and antibody affinity on antibody-dependent cellular cytotoxicity: relevance for immunotherapy of carcinomas

1998 • 90 citations

Monoclonal antibodies as therapeutics in oncology

2002 • 84 citations

Clinical experience with edrecolomab: a monoclonal antibody therapy for colorectal carcinoma

2001 • 82 citations

Granulocyte-monocyte-colony-stimulating factor augments the cytotoxic capacity of lymphocytes and monocytes in antibody-dependent cellular cytotoxicity

1989 • 70 citations

Immunohistochemical monitoring of metastatic colorectal carcinoma in patients treated with monoclonal antibodies (MAb 17-1A)

1988 • 61 citations

Pharmacokinetics of the mouse monoclonal antibody 17-1A in cancer patients receiving various treatment schedules.

1990 • 57 citations

CO 17-1A and related monoclonal antibodies: their production and characterization.

1986 • 55 citations

Therapeutics targeting signal transduction for patients with colorectal carcinoma

2002 • 53 citations

Magic Bullets Fly Again

2001 • 47 citations

A phase II trial of murine monoclonal antibody 17-1A and interferon-γ: Clinical and immunological data

1990 • 46 citations

Update of clinical trials with edrecolomab: A monoclonal antibody therapy for colorectal cancer

2001 • 42 citations

Tumor-Associated Antigen Expression of Primary and Metastatic Colon Carcinomas Detected by Monoclonal Antibody 17-1A

1987 • 37 citations

Steigert Körperliche Anstrengung die Disposition zu Epidemischer Kinderlähme

1938 • 23 citations

Antibodies in the therapy of colon cancer.

1999 • 22 citations

DIFFERENT DOSE REGIMENS OF THE MOUSE MONOCLONAL-ANTIBODY 17-1A FOR THERAPY OF PATIENTS WITH METASTATIC COLORECTAL-CARCINOMA

1995 • 15 citations

In vivo activity of humanized monoclonal anti-EGFR antibody EMD72000 in combination with gemcitabine on growth of primary pancreatic tumors and metastases in an orthotopic nude mouse model

2003 • 11 citations

Chemotherapy for colorectal cancer

2002 • 7 citations

Cited By (0)

Loading...
Monoclonal antibodies in the treatment of colorectal cancer (2004) – European Journal of Cancer | Metascience Observatory Explorer