The hydrolytic activity of bovine adrenal medullary plasma membranes towards diadenosine polyphosphates is due to alkaline phosphodiesterase-I

[12] Determination of total protein

1983 • 1,309 citations

Biogenesis of the rat hepatocyte plasma membrane in vivo: comparison of the pathways taken by apical and basolateral proteins using subcellular fractionation.

1987 • 383 citations

Fhit, a Putative Tumor Suppressor in Humans, Is a Dinucleoside 5‘,5‘ ‘‘-P¹,P³-Triphosphate Hydrolase

1996 • 350 citations

Diadenosine phosphates and the physiological control of blood pressure

1994 • 208 citations

Ap4A and Other Dinucleoside Polyphosphates

2020 • 195 citations

The presence of diadenosine 5′,5‴-P 1 ,P 3 -triphosphate (Ap 3 A) in human platelets

1983 • 159 citations

Ecto‐phosphodiesterase/pyrophosphatase of lymphocytes and non‐lymphoid cells: structure and function of the PC‐1 family

1998 • 152 citations

Presence of diadenosine polyphosphates— Ap4A and Ap5A— In rat brain synaptic terminals. Ca2+ dependent release evoked by 4-aminopyridine and veratridine

1992 • 147 citations

Subcellular Distribution Studies of Diadenosine Polyphosphates—Ap₄A and Ap₅A—in Bovine Adrenal Medulla: Presence in Chromaffin Granules

1988 • 138 citations

Pivotal role of phosphate chain length in vasoconstrictor versus vasodilator actions of adenine dinucleotides in rat mesenteric arteries.

1995 • 106 citations

Characterization and quantification of diadenosine hexaphosphate in chromaffin cells: Granular storage and secretagogue-induced release

1992 • 101 citations

Molecular cloning, expression, and localization of a brain-specific phosphodiesterase I/nucleotide pyrophosphatase (PD-I alpha) from rat brain.

1994 • 92 citations

Biochemical Characterization of Human PC‐1, an Enzyme Possessing Alkaline Phosphodiesterase I and Nucleotide Pyrophosphatase Activities

1994 • 86 citations

Plasma cell membrane glycoprotein PC-1. Primary structure deduced from cDNA clones.

1987 • 83 citations

Molecular Cloning and Chromosomal Localization of PD-Iβ (PDNP3), a New Member of the Human Phosphodiesterase I Genes

1997 • 77 citations

P2 purinergic receptors for diadenosine polyphosphates in the nervous system

1995 • 72 citations

Biochemical and molecular identification of distinct forms of alkaline phosphodiesterase I expressed on the apical and basolateral plasma membrane surfaces of rat hepatocytes

1997 • 68 citations

Two low Km hydrolytic activities on dinucleoside 5‘,5“‘-P1,P4-tetraphosphates in rat liver. Characterization as the specific dinucleoside tetraphosphatase and a phosphodiesterase I-like enzyme.

1984 • 66 citations

Effect of diadenosine polyphosphates on catecholamine secretion from isolated chromaffin cells

1990 • 65 citations

Identification and partial characterization of an adenosine(5′)tetraphospho(5′)adenosine hydrolase on intact bovine aortic endothelial cells

1989 • 57 citations

Adenine dinucleotides: a novel class of signalling molecules

1996 • 51 citations

Human diadenosine 5′,5′′′-P1,P4-tetraphosphate pyrophosphohydrolase is a member of the MutT family of nucleotide pyrophosphatases

1995 • 51 citations

Adenosine(5') oligophospho-(5') guanosines and guanosine(5') oligophospho-(5') guanosines in human platelets.

1998 • 51 citations

The diadenosine polyphosphates Ap3A and Ap4A and adenosine triphosphate interact with granulocyte-macrophage colony-stimulating factor to delay neutrophil apoptosis: implications for neutrophil: platelet interactions during inflammation

1996 • 48 citations

P ¹ , P ⁴ -Dithio- P ² , P ³ -monochloromethylene diadenosine 5′,5‴- P ¹ , P ⁴ -tetraphosphate: A novel antiplatelet agent

1997 • 43 citations

Extracellular hydrolysis of diadenosine polyphosphates, ApnA, by bovine chromaffin cells in culture

1992 • 43 citations

Ecto-enzymatic hydrolysis of diadenosine polyphosphates by cultured adrenomedullary vascular endothelial cells

1997 • 38 citations

Vasoactive Diadenosine Polyphosphates Promote Growth of Cultured Renal Mesangial Cells

1995 • 37 citations

Catabolism of Ap4A and Ap3A in human serum. Identification of isoenzymes and their partial characterization

1987 • 37 citations

Characterization of the bis(5′-nucleosidyl) tetraphosphate pyrophosphohydrolase from encysted embryos of the brine shrimp Artemia

1989 • 36 citations

Diadenosine polyphosphates evoke Ca²⁺ transients in guinea‐pig brain via receptors distinct from those for ATP

1997 • 32 citations

Hydrolysis of diadenosine 5',5''-P',P''-triphosphate (Ap3A) by porcine aortic endothelial cells.

1986 • 32 citations

Di(1,N⁶‐ethenoadenosine)5′, 5‴‐P¹,P⁴‐tetraphosphate, a fluorescent enzymatically active derivative of Ap₄A

1991 • 30 citations

Adenosine transporters in chromaffin cells: Subcellular distribution and characterization

1988 • 28 citations

Molecular cloning and expression of a porcine chondrocyte nucleotide pyrophosphohydrolase

1997 • 27 citations

Diadenosine polyphosphate hydrolase from presynaptic plasma membranes of Torpedo electric organ

1997 • 26 citations

Alkaline phosphodiesterase I release from eucaryotic plasma membranes by phosphatidylinositol-specific phospholipase C—IV. The release from Cacia porcellus organs

1994 • 17 citations

Diadenosine polyphosphates in the central nervous system

1997 • 15 citations

Proof of alkaline phosphodiesterase I as a phosphatidylinositol-anchor enzyme

1993 • 9 citations

Alkaline phosphodiesterase I release from eucaryotic plasma membranes by phosphatidylinositol-specipic phospholipase C III. The release from tumor cells

1993 • 7 citations

The synthesis of 4-methylumbelliferyl phenylphosphonate and its use in an improved method for the zymogram analysis of phosphodiesterase I

1983 • 6 citations

32 The MutT motif-containing ORF163w protein from the yeast Saccharomyces cerevisiae encodes a (di)nucleoside polyphosphate hydrolase

1997 • 4 citations