Metal Ion Modulation of Membrane Permeability Induced by a Polypetide Template

Comprehensive Coordination Chemistry

1988 • 7,119 citations

A voltage-gated ion channel model inferred from the crystal structure of alamethicin at 1.5-Å resolution

1982 • 710 citations

Liposome-Cell Interaction: Transfer and Intracellular Release of a Trapped Fluorescent Marker

1977 • 702 citations

Protein Design, a Minimalist Approach

1989 • 465 citations

The biophysics of peptide models of ion channels

1991 • 446 citations

A Chemical Approach to Protein Design—Template‐Assembled Synthetic Proteins (TASP)

1989 • 403 citations

Metal Ion-Dependent Modulation of the Dynamics of a Designed Protein

1993 • 252 citations

Helichrome: synthesis and enzymic activity of a designed hemeprotein

1989 • 242 citations

Synthetic peptides as models for ion channel proteins

1993 • 211 citations

A convergent approach to protein design. Metal ion-assisted spontaneous self-assembly of a polypeptide into a triple-helix bundle protein

1992 • 211 citations

High resolution and field desorption mass spectrometry studies and revised structures of alamethicins I and II

1977 • 206 citations

Template-assembled synthetic proteins with four-helix-bundle topology. Total chemical synthesis and conformational studies

1992 • 205 citations

Trichogin A IV, an 11-residue lipopeptaibol from Trichoderma longibrachiatum

1992 • 198 citations

Peptaibol antibiotics: a study on the helical structure of the 2-9 sequence of emerimicins III and IV.

1982 • 180 citations

Design of an artificial four-helix bundle metalloprotein via a novel ruthenium(II)-assisted self-assembly process

1992 • 151 citations

Tetraphilin: a four-helix proton channel built on a tetraphenylporphyrin framework

1992 • 150 citations

Structure determination of racemic trichogin A IV using centrosymmetric crystals

1994 • 137 citations

Peptide architecture. Design of stable .alpha.-helical metallopeptides via a novel exchange-inert ruthenium(III) complex

1990 • 132 citations

Channel protein engineering: synthetic 22-mer peptide from the primary structure of the voltage-sensitive sodium channel forms ionic channels in lipid bilayers.

1988 • 126 citations

Transmembrane Channels Based on Tartaric Acid-Gramicidin A Hybrids

1989 • 110 citations

Formation of local structures in protein folding

1989 • 102 citations

Template-assembled synthetic proteins designed to adopt a globular, four-helix bundle conformation form ionic channels in lipid bilayers

1993 • 98 citations

Pore formation kinetics in membranes, determined from the release of marker molecules out of liposomes or cells

1990 • 82 citations

Fungal Metabolites. XIII. Isolation and Structural Elucidation of New Peptaibols, Trichodecenins-I and -II, from Trichoderma viride.

1994 • 71 citations

Voltage-gated channels formed in lipid bilayers by a positively charged segment of the Na-channel polypeptide.

1989 • 70 citations

Fluorescence studies of the interaction of trichorzianine A IIIc with model membranes

1986 • 32 citations

A nonhelical, multiple β‐turn conformation in a glycine‐rich heptapeptide fragment of trichogin A IV containing a single central α‐aminoisobutyric acid residue

1995 • 28 citations

Molecular mimicry in channel-protein structure

1995 • 26 citations

A zinc(II)-organized molecular receptor as a catalyst for the cleavage of amino acid esters

1995 • 15 citations

Synthesis and membrane-modifying properties of analogues of the lipopeptaibol trichogin GA IV with variable N α-acyl chain length

1995 • 3 citations