MET and MYC cooperate in mammary tumorigenesis

Met, metastasis, motility and more

2003 • 2,526 citations

In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells

2003 • 2,344 citations

Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes

1984 • 906 citations

The pCL vector system: rapid production of helper-free, high-titer, recombinant retroviruses

1996 • 728 citations

Stem cells in normal breast development and breast cancer

2003 • 551 citations

An entire functional mammary gland may comprise the progeny from a single cell

1998 • 544 citations

Stem cells in normal breast development and breast cancer

2003 • 544 citations

Sca-1pos Cells in the Mouse Mammary Gland Represent an Enriched Progenitor Cell Population

2002 • 523 citations

Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells

2003 • 511 citations

The mammary pathology of genetically engineered mice: the consensus report and recommendations from the Annapolis meeting

2000 • 491 citations

Mammary ductal elongation: Differentiation of myoepithelium and basal lamina during branching morphogenesis

1983 • 453 citations

RETRACTED: Uncoupling IL-2 Signals that Regulate T Cell Proliferation, Survival, and Fas-Mediated Activation-Induced Cell Death

1999 • 443 citations

c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations

2001 • 408 citations

The interplay of matrix metalloproteinases, morphogens and growth factors is necessary for branching of mammary epithelial cells

2001 • 373 citations

c-Myc in breast cancer.

2000 • 337 citations

Hepatocyte growth factor induces Wnt-independent nuclear translocation of beta-catenin after Met-beta-catenin dissociation in hepatocytes.

2002 • 295 citations

Breast cancer, stem/progenitor cells and the estrogen receptor

2004 • 293 citations

Activation of the Met Receptor by Cell Attachment Induces and Sustains Hepatocellular Carcinomas in Transgenic Mice

2001 • 277 citations

The in vivo life span of normal and preneoplastic mouse mammary glands: a serial transplantation study.

1968 • 276 citations

The mutationally activated Met receptor mediates motility and metastasis

1998 • 228 citations

Expression of c-met is a strong independent prognostic factor in breast carcinoma

1998 • 210 citations

Embryonic stem cell virus, a recombinant murine retrovirus with expression in embryonic stem cells.

1990 • 203 citations

A novel doxycycline‐inducible system for the transgenic analysis of mammary gland biology

2002 • 201 citations

Amplification of c-myc, K-sam, and c-met in gastric cancers: detection by fluorescence in situ hybridization.

1998 • 185 citations

Met expression is associated with poor outcome in patients with axillary lymph node negative breast carcinoma

1999 • 156 citations

Expression of the C-Met/HGF receptor in human breast carcinoma: Correlation with tumor progression

1997 • 153 citations

Oncogenic Mutants of RON and MET Receptor Tyrosine Kinases Cause Activation of the β-Catenin Pathway

2001 • 148 citations

Transgenic expression of tpr-met oncogene leads to development of mammary hyperplasia and tumors.

1996 • 112 citations

Differential keratin gene expression in developing, differentiating, preneoplastic, and neoplastic mouse mammary epithelium.

1990 • 106 citations

Activating Met mutations produce unique tumor profiles in mice with selective duplication of the mutant allele

2004 • 105 citations

Tissue microarray‐based studies of patients with lymph node negative breast carcinoma show that met expression is associated with worse outcome but is not correlated with epidermal growth factor family receptors

2003 • 99 citations

Targeted expression of HGF/SF in mouse mammary epithelium leads to metastatic adenosquamous carcinomas through the activation of multiple signal transduction pathways

2003 • 99 citations

Identification of Stem Cell Units in the Terminal End Bud and Duct of the Mouse Mammary Gland

2001 • 93 citations

Tissue-specific, high level expression of the rat whey acidic protien gene in transgenic mice

1990 • 84 citations

Mapping of chromosomal imbalances in gastric adenocarcinoma revealed amplified protooncogenesMYCN,MET,WNT2, andERBB2

1998 • 84 citations

Validity of mouse mammary tumour models for human breast cancer: Comparative pathology

2001 • 71 citations

Steroid hormone receptor status defines the MMTV promoter chromatin structure in vivo

1995 • 50 citations

Epithelial Cell Culture

2018 • 42 citations

Transforming growth factor alpha- and c-myc-induced mammary carcinogenesis in transgenic mice

2000 • 42 citations

Adenovirus-Cre-mediated recombination in mammary epithelial early progenitor cells

2001 • 33 citations