Dopamine Genes (DRD2/ANKK1-TaqA1 and DRD4-7R) and Executive Function: Their Interaction with Obesity

The Hospital Anxiety and Depression Scale

1983 • 42,177 citations

Parallel Organization of Functionally Segregated Circuits Linking Basal Ganglia and Cortex

1986 • 8,208 citations

Validity of the Trail Making Test as an Indicator of Organic Brain Damage

1958 • 7,146 citations

Actual Causes of Death in the United States

1993 • 5,506 citations

Actual Causes of Death in the United States, 2000

2004 • 5,189 citations

The three-factor eating questionnaire to measure dietary restraint, disinhibition and hunger

1985 • 4,496 citations

Psychological Assessment Resources

1995 • 2,905 citations

Frontal-Subcortical Circuits and Human Behavior

1993 • 2,248 citations

Neuropsychological assessment, 4th ed.

2004 • 1,982 citations

Brain dopamine and obesity

2001 • 1,817 citations

Association Between Obesity and Psychiatric Disorders in the US Adult Population

2006 • 1,304 citations

Multilingual Aphasia Examination

2018 • 1,206 citations

A Self-rating Scale for Bulimia the ‘BITE’

1987 • 809 citations

An 18-Year Follow-up of Overweight and Risk of Alzheimer Disease

2003 • 793 citations

Relation Between Obesity and Blunted Striatal Response to Food Is Moderated by Taq IA A1 Allele

2008 • 762 citations

Meta-Analysis of the Association Between the 7-Repeat Allele of the Dopamine D₄ Receptor Gene and Attention Deficit Hyperactivity Disorder

2001 • 754 citations

Polymorphisms in the dopamine D2 receptor gene and their relationships to striatal dopamine receptor density of healthy volunteers

1999 • 728 citations

The A1 allele of the human D2 dopamine receptor gene predicts low D2 receptor availability in healthy volunteers

1998 • 679 citations

Elevated body mass index is associated with executive dysfunction in otherwise healthy adults

2006 • 647 citations

Identification and characterization of ANKK1: A novel kinase gene closely linked to DRD2 on chromosome band 11q23.1

2004 • 617 citations

Feeding-induced dopamine release in dorsal striatum correlates with meal pleasantness ratings in healthy human volunteers

2003 • 608 citations

Meta-analysis shows significant association between dopamine system genes and attention deficit hyperactivity disorder (ADHD)

2006 • 579 citations

Low dopamine striatal D2 receptors are associated with prefrontal metabolism in obese subjects: Possible contributing factors

2008 • 554 citations

D2 dopamine receptor gene in psychiatric and neurologic disorders and its phenotypes

2002 • 501 citations

Genetically Determined Differences in Learning from Errors

2007 • 435 citations

The world-wide distribution of allele frequencies at the human dopamine D4 receptor locus

1996 • 432 citations

The dopamine D4 receptor: one decade of research

2000 • 425 citations

Sugar and Fat Bingeing Have Notable Differences in Addictive-like Behavior

2009 • 375 citations

Assessing the molecular genetics of attention networks.

2002 • 340 citations

Inverse Association Between BMI and Prefrontal Metabolic Activity in Healthy Adults

2008 • 338 citations

A 24-year follow-up of body mass index and cerebral atrophy

2004 • 330 citations

Food reinforcement, the dopamine D₂ receptor genotype, and energy intake in obese and nonobese humans.

2007 • 316 citations

Studies of the 48 bp repeat polymorphism of theDRD4 gene in impulsive, compulsive, addictive behaviors: Tourette syndrome, ADHD, pathological gambling, and substance abuse

1999 • 291 citations

Association of seven polymorphisms of the D2 dopamine receptor gene with brain receptor-binding characteristics.

2003 • 288 citations

Dopamine Receptor mRNA Expression in Human Striatum and Neocortex

1996 • 277 citations

Attention deficit/hyperactivity disorder children with a 7-repeat allele of the dopamine receptor D4 gene have extreme behavior but normal performance on critical neuropsychological tests of attention

2000 • 272 citations

Association of the DRD2 gene Taq1A polymorphism and alcoholism: a meta-analysis of case–control studies and evidence of publication bias

2002 • 252 citations

Examining impulsivity as an endophenotype using a behavioral approach: a DRD2 TaqI A and DRD4 48-bp VNTR association study.

2007 • 249 citations

Analysis of DRD4 and DAT polymorphisms and behavioral inhibition in healthy adults: Implications for impulsivity

2007 • 225 citations

The human dopamine D4 receptor repeat sequences modulate expression

2003 • 222 citations

Neuropsychological performance of a clinical sample of extremely obese individuals

2008 • 218 citations

Dopamine D2 receptors in the cerebral cortex: distribution and pharmacological characterization with [3H]raclopride.

1989 • 208 citations

Elevated BMI Is Associated With Decreased Blood Flow in the Prefrontal Cortex Using SPECT Imaging in Healthy Adults

2011 • 201 citations

D2 dopamine receptor gene and obesity

1994 • 195 citations

Association of the Dopamine D₄ Receptor Gene 7-Repeat Allele With Neuropsychological Test Performance of Children With ADHD

2004 • 184 citations

Dopamine DRD2 Polymorphism Alters Reversal Learning and Associated Neural Activity

2009 • 182 citations

A simple estimate of mortality attributable to excess weight in the European Union

2003 • 173 citations

Altered executive function in obesity. Exploration of the role of affective states on cognitive abilities

2009 • 166 citations

D2 dopamine receptor polymorphism and brain regional glucose metabolism

1997 • 164 citations

Dopamine Receptor Gene Expression in the Human Medial Temporal Lobe

1994 • 161 citations

Frontostriatal Involvement in Task Switching Depends on Genetic Differences in D2 Receptor Density

2010 • 153 citations

Increased prevalence of the Taq I A1allele of the dopamine receptor gene (DRD2) in obesity with comorbid substance use disorder: a preliminary report

1996 • 153 citations

Elevated Putamen D₂Receptor Binding Potential in Major Depression With Motor Retardation: An [¹¹C]Raclopride Positron Emission Tomography Study

2006 • 152 citations

Dopamine Receptor Transcript Expression in Striatum and Prefrontal and Occipital Cortex

1997 • 142 citations

WAIS-III: Escala de Inteligencia de Wechsler para Adultos III. Manual técnico

1999 • 140 citations

The Dopamine D2 Receptor (DRD2) as a Major Gene in Obesity and Height

1993 • 134 citations

Does the Letter Number Sequencing Task Measure Anything More Than Digit Span?

2000 • 130 citations

Statistical Approaches to Complex Phenotypes: Evaluating Neuropsychological Endophenotypes for Attention-Deficit/Hyperactivity Disorder

2005 • 127 citations

The short DRD4 repeats confer risk to attention deficit hyperactivity disorder in a family-based design and impair performance on a continuous performance test (TOVA)

2002 • 121 citations

Spectrum of binge eating symptomatology in patients treated with clozapine and olanzapine

2003 • 115 citations

Reduced visuospatial performance in children with the D2 dopamine receptor A1 allele

1995 • 107 citations

Advances in molecular genetics and the prevention and treatment of substance misuse: Implications of association studies of the A1 allele of the D2 dopamine receptor gene

2004 • 107 citations

The dopamine-4 receptor gene associated with binge eating and weight gain in women with seasonal affective disorder: An evolutionary perspective

2004 • 102 citations

[3H]Naloxone binding in the human brain: alcoholism and theTaqI A D2 dopamine receptor polymorphism

1996 • 101 citations

The Role of the Human Orbitofrontal Cortex in Taste and Flavor Processing

2007 • 100 citations

The influence of the dopaminergic system on cognitive functioning: A molecular genetic approach

2005 • 100 citations

Escala de inteligencia de Wechsler para adultos-IV (WAIS-IV)

2013 • 98 citations

Interactive Effects of a DRD4 Polymorphism, Lead, and Sex on Executive Functions in Children

2007 • 80 citations

The effect of reduced dopamine D4 receptor expression in the 5-choice continuous performance task: Separating response inhibition from premature responding

2011 • 78 citations

Cognitive Performance of Morbidly Obese Patients Seeking Bariatric Surgery

2010 • 72 citations

Variant alleles of the D2 dopamine receptor gene and obesity

2000 • 71 citations

DRD3, but not COMT or DRD2, genotype affects executive functions in healthy and first‐episode psychosis adolescents

2008 • 62 citations

Dopamine DRD2 Taq I polymorphism associates with caudate nucleus volume and cognitive performance in memory impaired subjects

2002 • 51 citations

The Taq IA polymorphism linked to the DRD2 gene is related to lower attention and less inhibitory control in alcoholic patients

2005 • 47 citations

On the molecular genetics of flexibility: The case of task-switching, inhibitory control and genetic variants

2011 • 41 citations

Dopamine D2 Receptor and N-Methyl-<i>D</i>-Aspartate Receptor 2B Subunit Genetic Variants and Intelligence

2002 • 33 citations

Genetic factors of reaction time performance: DRD4 7-repeat allele associated with slower responses

2010 • 29 citations

Mapping of Central D2Dopamine Receptors in Man Using [11C]Raclopride: PET with Anatomic Standardization Technique

1999 • 28 citations

The effect of age on frontal lobe related cognitive functions of unmedicated depressed patients

2010 • 26 citations